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Phase 2 of CATALISE: a multinational and multidisciplinary Delphi consensus study of problems with language development: terminology
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Neural correlates of language variability in preschool-aged boys with autism spectrum disorder.
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In: Autism research : official journal of the International Society for Autism Research, vol 10, iss 6 (2017)
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Abstract:
Children with autism vary widely in their language abilities, yet the neural correlates of this language variability remain unclear, especially early in development. Diffusion tensor imaging (DTI) was used to examine diffusivity measures along the length of 18 major fiber tracts in 104 preschool-aged boys with autism spectrum disorder (ASD). The boys were assigned to subgroups according to their level of language development (Low: no/low language, Middle: small vocabulary, High: large vocabulary and grammar), based on their raw scores on the expressive language (EL) and receptive language (RL) sections of the Mullen Scales of Early Learning (MSEL). Results indicate that the subgroups differed in fractional anisotropy (FA), mean diffusivity (MD), and radial diffusivity (RD) along the inferior longitudinal fasciculus (ILF) in both hemispheres. Moreover, FA correlated significantly with Mullen EL and RL raw scores, but not ADOS severity score, along the left and right ILF. Subgroups also differed in MD (but not FA) along the left superior longitudinal fasiculus and left corticospinal tract, but these differences were not correlated with language scores. These findings suggest that white matter microstructure in the left and right ILF varies in relation to lexical development in young males with ASD. The findings also support the use of raw scores on language-relevant standardized tests for assessing early language-brain relationships. Autism Res 2017. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. Autism Res 2017, 10: 1107-1119. © 2017 International Society for Autism Research, Wiley Periodicals, Inc.
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Keyword:
Autism; Autism Spectrum Disorder; Brain; Brain Disorders; brain imaging; Child; Child Language; Clinical Research; Clinical Sciences; Developmental & Child Psychology; Diffusion Tensor Imaging; DTI; Humans; Intellectual and Developmental Disabilities; language development; Male; Mental Health; Neural Pathways; Neurosciences; Pediatric; Preschool; preschoolers; Prevention; Psychology; White Matter
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URL: https://escholarship.org/uc/item/8zw8h2hm
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Grammatical Language Impairment in Autism Spectrum Disorder: Exploring Language Phenotypes Beyond Standardized Testing.
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In: Frontiers in psychology, vol 8, iss APR (2017)
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Do Children with Developmental Language Disorder Demonstrate Domain-Specific (Verbal) or Domain-General Memory Deficits?
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In: http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1510895890722091 (2017)
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Rhythmic Sensitivity and Developmental Language Disorder in Children ...
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Grammar as a Maturational Controlled Behavior: Minimality in Development and Impairment
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In: BIOLINGUISTICS; Vol. 11 (2017): Special Issue—50 Years Later: A Tribute to Eric Lenneberg’s Biological Foundations of Language; 353-366 ; 1450-3417 (2017)
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What mother-child talk tells us about children’s language, social, emotional and behavioural development: a community-based study of slow-to-talk children
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Phase 2 of CATALISE: a multinational and multidisciplinary Delphi consensus study of problems with language development: Terminology
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Phase 2 of CATALISE: a multinational and multidisciplinary Delphi consensus study of problems with language development: Terminology
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Rhythmic Sensitivity and Developmental Language Disorder in Children
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Richards, Susan Mary. - : University of Cambridge, 2017. : Department of Psychology, 2017. : Clare Hall, 2017
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Phase 2 of CATALISE: a multinational and multidisciplinary Delphi consensus study of problems with language development: Terminology
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Early development of infants with neurofibromatosis type 1: A case series
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Linguistic and Cognitive Measures in Arabic-Speaking English Language Learners (ELLs) and monolingual children with and without Developmental Language Disorder (DLD)
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In: Electronic Thesis and Dissertation Repository (2017)
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Phase 2 of CATALISE: a multinational and multidisciplinary Delphi consensus study of problems with language development: Terminology
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In: Communication Sciences and Disorders Publications (2017)
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Word Learning in Children with Specific Language Impairment: Influence of Child and Word Characteristics
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Phase 2 of CATALISE: a multinational and multidisciplinary Delphi consensus study of problems with language development: terminology
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A relationship between early language skills and adult autistic-like traits: evidence from a longitudinal population-based study
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Grammar as a Maturational Controlled Behavior: Minimality in Development and Impairment
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In: Biolinguistics, Vol 11, Iss SI, Pp 353-366 (2017) (2017)
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Grammar as a Maturational Controlled Behavior: Minimality in Development and Impairment
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In: Biolinguistics, Vol 11, Iss SI (2017) (2017)
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