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What semantic dementia teaches us about the functional organization of the left posterior fusiform gyrus
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In: ISSN: 0028-3932 ; EISSN: 1873-3514 ; Neuropsychologia ; https://www.hal.inserm.fr/inserm-01613998 ; Neuropsychologia, Elsevier, 2017, 106, pp.159-168. ⟨10.1016/j.neuropsychologia.2017.09.023⟩ (2017)
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A SEMantic and EPisodic Memory Test (SEMEP) Developed within the Embodied Cognition Framework: Application to Normal Aging, Alzheimer's Disease and Semantic Dementia
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In: ISSN: 1664-1078 ; Frontiers in Psychology ; https://hal.archives-ouvertes.fr/hal-02131641 ; Frontiers in Psychology, Frontiers, 2017, 8, pp.1493. ⟨10.3389/fpsyg.2017.01493⟩ (2017)
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Use of Speech Analyses within a mobile application for the Assessment of cognitive impairment in elderly people
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In: ISSN: 1567-2050 ; Current Alzheimer Research ; https://hal.inria.fr/hal-01672580 ; Current Alzheimer Research, Bentham Science Publishers, 2017, 14, pp.120 - 129. ⟨10.2174/1567205014666170829111942⟩ (2017)
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| 4 |
Free and Cued Selective Reminding Test – accuracy for the differential diagnosis of Alzheimer's and neurodegenerative diseases: A large-scale biomarker-characterized monocenter cohort study (ClinAD)
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In: ISSN: 1552-5260 ; Alzheimer's and Dementia ; https://hal.inria.fr/hal-01672862 ; Alzheimer's and Dementia, Elsevier, 2017, 13 (8), pp.913 - 923. ⟨10.1016/j.jalz.2016.12.014⟩ (2017)
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| 5 |
Neuropsychological assessment of 86-year-old man with Broca's aphasia complaining of memory difficulties
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In: Woods, D, Sirirat, S, Pattara-angkoon, S, Rattanajan, J, (2017). Neuropsychological assessment of 86-year-old man with Broca's aphasia complaining of memory difficulties. Applied Neuropsychology:Adult, Vol. 24, No. 6, p. 577-586 http://dx.doi.org/10.1080/23279095.2016.1225070 (2017)
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| 6 |
Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease.
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| 7 |
Data-driven classification of patients with primary progressive aphasia
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In: Hoffman, P; Sajjadi, SA; Patterson, K; & Nestor, PJ. (2017). Data-driven classification of patients with primary progressive aphasia. BRAIN AND LANGUAGE, 174, 86 - 93. doi:10.1016/j.bandl.2017.08.001. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5m4842c0 (2017)
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| 8 |
Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease.
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| 9 |
Data-driven classification of patients with primary progressive aphasia.
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| 10 |
Data-driven regions of interest for longitudinal change in three variants of frontotemporal lobar degeneration
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In: Binney, RJ; Pankov, A; Marx, G; He, X; McKenna, F; Staffaroni, AM; et al.(2017). Data-driven regions of interest for longitudinal change in three variants of frontotemporal lobar degeneration. BRAIN AND BEHAVIOR, 7(4), e00675. doi:10.1002/brb3.675. UCSF: Retrieved from: http://www.escholarship.org/uc/item/1xd9f3hr (2017)
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| 11 |
A neural network underlying intentional emotional facial expression in neurodegenerative disease.
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| 12 |
A neural network underlying intentional emotional facial expression in neurodegenerative disease.
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Gola, Kelly A; Shany-Ur, Tal; Pressman, Peter; Sulman, Isa; Galeana, Eduardo; Paulsen, Hillary; Nguyen, Lauren; Wu, Teresa; Adhimoolam, Babu; Poorzand, Pardis; Miller, Bruce L; Rankin, Katherine P. - : eScholarship, University of California, 2017
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Abstract:
Intentional facial expression of emotion is critical to healthy social interactions. Patients with neurodegenerative disease, particularly those with right temporal or prefrontal atrophy, show dramatic socioemotional impairment. This was an exploratory study examining the neural and behavioral correlates of intentional facial expression of emotion in neurodegenerative disease patients and healthy controls. One hundred and thirty three participants (45 Alzheimer's disease, 16 behavioral variant frontotemporal dementia, 8 non-fluent primary progressive aphasia, 10 progressive supranuclear palsy, 11 right-temporal frontotemporal dementia, 9 semantic variant primary progressive aphasia patients and 34 healthy controls) were video recorded while imitating static images of emotional faces and producing emotional expressions based on verbal command; the accuracy of their expression was rated by blinded raters. Participants also underwent face-to-face socioemotional testing and informants described participants' typical socioemotional behavior. Patients' performance on emotion expression tasks was correlated with gray matter volume using voxel-based morphometry (VBM) across the entire sample. We found that intentional emotional imitation scores were related to fundamental socioemotional deficits; patients with known socioemotional deficits performed worse than controls on intentional emotion imitation; and intentional emotional expression predicted caregiver ratings of empathy and interpersonal warmth. Whole brain VBMs revealed a rightward cortical atrophy pattern homologous to the left lateralized speech production network was associated with intentional emotional imitation deficits. Results point to a possible neural mechanisms underlying complex socioemotional communication deficits in neurodegenerative disease patients.
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Keyword:
80 and over; Aged; Alzheimer Disease; Aphasia; Brain Mapping; Caregivers; Computer-Assisted; Emotion; Emotions; Empathy; Facial Expression; Female; Frontotemporal Dementia; Humans; Image Processing; Intention; Magnetic Resonance Imaging; Male; Middle Aged; Neurodegenerative Diseases; Neuropsychological Tests; Neurosciences; Primary Progressive; Primary Progressive Nonfluent Aphasia; Social Behavior; Social functioning
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URL: https://escholarship.org/uc/item/9kp6g3dm
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| 13 |
A neural network underlying intentional emotional facial expression in neurodegenerative disease
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In: Gola, KA; Shany-Ur, T; Pressman, P; Sulman, I; Galeana, E; Paulsen, H; et al.(2017). A neural network underlying intentional emotional facial expression in neurodegenerative disease. NEUROIMAGE-CLINICAL, 14, 672 - 678. doi:10.1016/j.nicl.2017.01.016. UCSF: Retrieved from: http://www.escholarship.org/uc/item/9kp6g3dm (2017)
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| 14 |
Data-driven regions of interest for longitudinal change in three variants of frontotemporal lobar degeneration.
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In: Brain and behavior, vol 7, iss 4 (2017)
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| 15 |
Observing conversational laughter in frontotemporal dementia.
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In: Journal of neurology, neurosurgery, and psychiatry, vol 88, iss 5 (2017)
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| 16 |
Emotion detection deficits and changes in personality traits linked to loss of white matter integrity in primary progressive aphasia.
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| 17 |
Observing conversational laughter in frontotemporal dementia.
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In: Journal of neurology, neurosurgery, and psychiatry, vol 88, iss 5 (2017)
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| 18 |
Data-driven regions of interest for longitudinal change in three variants of frontotemporal lobar degeneration.
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In: Brain and behavior, vol 7, iss 4 (2017)
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| 19 |
La reconstruction de la signification dans la démence
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In: ISSN: 1268-6034 ; Soins Gérontologie ; https://hal-unilim.archives-ouvertes.fr/hal-01800477 ; Soins Gérontologie, Elsevier Masson, 2017, 22 (127), pp.41 - 44. ⟨10.1016/j.sger.2017.06.012⟩ (2017)
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| 20 |
Connected Language in Primary Progressive Aphasia: Testing the Utility of Linguistic Measures in Differentially Diagnosing PPA and its Variants ...
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