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Anomalous morphology in left hemisphere motor and premotor cortex of children who stutter
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| 2 |
Anterior insular thickness predicts speech sound learning ability in bilinguals.
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In: NeuroImage, vol 165 (2018)
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Evidence Supporting LI-RADS Major Features for CT- and MR Imaging-based Diagnosis of Hepatocellular Carcinoma: A Systematic Review.
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In: Radiology, vol 286, iss 1 (2018)
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Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia.
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In: JAMA neurology, vol 75, iss 3 (2018)
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Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia.
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In: JAMA neurology, vol 75, iss 3 (2018)
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Neuroscientific insights into the development of analogical reasoning.
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In: Developmental science, vol 21, iss 2 (2018)
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Large-scale associations between the leukocyte transcriptome and BOLD responses to speech differ in autism early language outcome subtypes.
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Lombardo, Michael V; Pramparo, Tiziano; Gazestani, Vahid; Warrier, Varun; Bethlehem, Richard AI; Carter Barnes, Cynthia; Lopez, Linda; Lewis, Nathan E; Eyler, Lisa; Pierce, Karen; Courchesne, Eric
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In: Nature neuroscience, vol 21, iss 12 (2018)
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Abstract:
Heterogeneity in early language development in autism spectrum disorder (ASD) is clinically important and may reflect neurobiologically distinct subtypes. Here, we identified a large-scale association between multiple coordinated blood leukocyte gene coexpression modules and the multivariate functional neuroimaging (fMRI) response to speech. Gene coexpression modules associated with the multivariate fMRI response to speech were different for all pairwise comparisons between typically developing toddlers and toddlers with ASD and poor versus good early language outcome. Associated coexpression modules were enriched in genes that are broadly expressed in the brain and many other tissues. These coexpression modules were also enriched in ASD-associated, prenatal, human-specific, and language-relevant genes. This work highlights distinctive neurobiology in ASD subtypes with different early language outcomes that is present well before such outcomes are known. Associations between neuroimaging measures and gene expression levels in blood leukocytes may offer a unique in vivo window into identifying brain-relevant molecular mechanisms in ASD.
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Keyword:
1.1 Normal biological development and functioning; 2.1 Biological and endogenous factors; Autism; Autism Spectrum Disorder; Brain; Brain Disorders; Brain Mapping; Child; Clinical Research; Cognitive Sciences; Female; Genetics; Humans; Infant; Intellectual and Developmental Disabilities (IDD); Language; Leukocytes; Magnetic Resonance Imaging; Male; Mental Health; Neuroimaging; Neurological; Neurology & Neurosurgery; Neurosciences; Pediatric; Preschool; Psychology; Speech; Transcriptome
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URL: https://escholarship.org/uc/item/2n39p5qz
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| 8 |
Large-scale associations between the leukocyte transcriptome and BOLD responses to speech differ in autism early language outcome subtypes.
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In: Nature neuroscience, vol 21, iss 12 (2018)
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| 9 |
Brain basis of cognitive resilience: Prefrontal cortex predicts better reading comprehension in relation to decoding.
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In: PloS one, vol 13, iss 6 (2018)
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Dynamic integration of conceptual information during learning.
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In: PloS one, vol 13, iss 11 (2018)
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| 11 |
Use of Vitamin K Antagonists and Brain Morphological Changes in Older Adults: An Exposed/Unexposed Voxel-Based Morphometric Study
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In: ISSN: 1421-9824 ; Dementia and geriatric cognitive disorders ; https://hal.univ-angers.fr/hal-02869144 ; Dementia and geriatric cognitive disorders, 2018, 45, pp.18-26. ⟨10.1159/000485793⟩ ; https://www.karger.com/Article/Abstract/485793 (2018)
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| 12 |
Neural Prediction Errors Distinguish Perception and Misperception of Speech. ...
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| 13 |
Phase Entrainment of Brain Oscillations Causally Modulates Neural Responses to Intelligible Speech. ...
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| 14 |
Focal versus distributed temporal cortex activity for speech sound category assignment
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In: ISSN: 0027-8424 ; Proceedings of the National Academy of Sciences, Vol. 115, No 6 (2018) pp. E1299-E1308 (2018)
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| 15 |
Neural Prediction Errors Distinguish Perception and Misperception of Speech.
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| 16 |
Phase Entrainment of Brain Oscillations Causally Modulates Neural Responses to Intelligible Speech.
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| 17 |
The involvement of left inferior frontal and middle temporal cortices in word production unveiled by greater facilitation effects following brain damage.
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In: Neuropsychologia, vol. 121, pp. 122-134 (2018)
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| 18 |
Linking Entropy at Rest with the Underlying Structural Connectivity in the Healthy and Lesioned Brain.
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In: Cerebral cortex, vol. 28, no. 8, pp. 2948-2958 (2018)
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