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Auditory feedback control mechanisms do not contribute to cortical hyperactivity within the voice production network in adductor spasmodic dysphonia
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Abstract:
Adductor spasmodic dysphonia (ADSD), the most common form of spasmodic dysphonia, is a debilitating voice disorder characterized by hyperactivity and muscle spasms in the vocal folds during speech. Prior neuroimaging studies have noted excessive brain activity during speech in ADSD participants compared to controls. Speech involves an auditory feedback control mechanism that generates motor commands aimed at eliminating disparities between desired and actual auditory signals. Thus, excessive neural activity in ADSD during speech may reflect, at least in part, increased engagement of the auditory feedback control mechanism as it attempts to correct vocal production errors detected through audition. To test this possibility, functional magnetic resonance imaging was used to identify differences between ADSD participants and age-matched controls in (i) brain activity when producing speech under different auditory feedback conditions, and (ii) resting state functional connectivity within the cortical network responsible for vocalization. The ADSD group had significantly higher activity than the control group during speech (compared to a silent baseline task) in three left-hemisphere cortical regions: ventral Rolandic (sensorimotor) cortex, anterior planum temporale, and posterior superior temporal gyrus/planum temporale. This was true for speech while auditory feedback was masked with noise as well as for speech with normal auditory feedback, indicating that the excess activity was not the result of auditory feedback control mechanisms attempting to correct for perceived voicing errors in ADSD. Furthermore, the ADSD group had significantly higher resting state functional connectivity between sensorimotor and auditory cortical regions within the left hemisphere as well as between the left and right hemispheres, consistent with the view that excessive motor activity frequently co-occurs with increased auditory cortical activity in individuals with ADSD. ; First author draft
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Keyword:
Auditory feedback; Clinical sciences; Cognitive sciences; Feedforward; Linguistics; Spasmodic dysphonia; Speech-language pathology & audiology; Voice
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URL: https://hdl.handle.net/2144/40173
https://doi.org/10.1044/2019_JSLHR-19-00325
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| 2 |
Bannock (Fort Hall, Idaho)
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In: English Faculty Publications and Presentations (2020)
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Fort Mcdermitt Reservation (Mcdermitt, Nevada)
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In: English Faculty Publications and Presentations (2020)
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| 4 |
Wadadɨka’a (Burns Paiute Reservation, Oregon)
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In: English Faculty Publications and Presentations (2020)
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| 5 |
Northern Paiute Texts: Introduction
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In: English Faculty Publications and Presentations (2020)
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| 6 |
Duck Valley Reservation (Owyhee, Nevada)
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In: English Faculty Publications and Presentations (2020)
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| 7 |
Yahooskin (Beatty, Oregon)
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In: English Faculty Publications and Presentations (2020)
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| 8 |
MTrill project: machine translation impact on language learning
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In: Resende, Natália orcid:0000-0002-5248-2457 and Way, Andy orcid:0000-0001-5736-5930 (2020) MTrill project: machine translation impact on language learning. In: European Association for Machine Translation (EAMT) 2020, 3-5 Nov 2020, Lisbon, Portugal (Online). ISBN 978-989-33-0589-8 (2020)
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| 9 |
An Investigation of Russian and American Legal Systems and Texts
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In: http://rave.ohiolink.edu/etdc/view?acc_num=ksuhonors1588374705630893 (2020)
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| 10 |
Rejecting false alternatives in Chinese and English: The interaction of prosody, clefting, and default focus position
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In: Laboratory Phonology: Journal of the Association for Laboratory Phonology; Vol 11, No 1 (2020); 17 ; 1868-6354 (2020)
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| 11 |
Best Practices for a Translingual Pedagogy: an Undergraduate Perspective
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In: University Honors Theses (2020)
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| 12 |
The effect of genre-based instruction on academic speech ...
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| 13 |
EFFECTS OF WORD CARD METHODOLOGY AND TESTING ON VOCABULARY KNOWLEDGE AND MOTIVATION ...
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ACADEMIC DISCOURSE IN KINDERGARTEN: LINGUISTIC FEATURES AND REPERTOIRES AT PLAY IN ACQUIRING LANGUAGE PROFICIENCY AND CONSTRUCTING MEANING IN FORMAL LITERACY CONTEXTS ...
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| 15 |
The Development of Interactive English Speaking Abilities in a Japanese University Context ...
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| 17 |
Classical Armenian – Morphology, Part 3 ... : Verbal Morphology – Part 1: Overview, Categories ...
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Classical Armenian – Morphology, Part 4 ... : Verbal Morphology – Part 2: Stem Formation, Inflection ...
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| 20 |
Old Irish – Morphosyntactic Structures, Part 3 ...
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Griffith, Aaron. - : Georg-August-Universität Göttingen,Sprachwissenschaftliches Seminar, 2020
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