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Using of Open-Source Technologies for the Design and Development of a Speech Processing System Based on Stemming Methods
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In: IFIP Advances in Information and Communication Technology ; 16th IFIP International Conference on Open Source Systems (OSS) ; https://hal.inria.fr/hal-03647270 ; 16th IFIP International Conference on Open Source Systems (OSS), May 2020, Innopolis, Russia. pp.98-105, ⟨10.1007/978-3-030-47240-5_10⟩ (2020)
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Amount and delay insensitivity during intertemporal choice in three neurodegenerative diseases reflects dorsomedial prefrontal atrophy.
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Depressive Symptom Profiles Predict Specific Neurodegenerative Disease Syndromes in Early Stages.
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Depressive Symptom Profiles Predict Specific Neurodegenerative Disease Syndromes in Early Stages.
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Shdo, Suzanne M; Ranasinghe, Kamalini G; Sturm, Virginia E; Possin, Katherine L; Bettcher, Brianne M; Stephens, Melanie L; Foley, Jessica M; You, Shou-Chin Christine; Rosen, Howard J; Miller, Bruce L; Kramer, Joel H; Rankin, Katherine P. - : eScholarship, University of California, 2020
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Abstract:
Background: During early stages, patients with neurodegenerative diseases (NDG) often present with depressive symptoms. However, because depression is a heterogeneous disorder, more precise delineation of the specific depressive symptom profiles that arise early in distinct NDG syndromes is necessary to enhance patient diagnosis and care. Methods and Findings: Five-hundred and sixty four participants self-reported their depressive symptoms using the Geriatric Depression Scale (GDS), including 111 healthy older control subjects (NC) and 453 patients diagnosed with one of six NDGs who were at the mild stage of disease (CDR® Dementia Staging Instrument ≤ 1) [186 Alzheimer's disease (AD), 76 behavioral variant frontotemporal dementia (bvFTD), 52 semantic variant primary progressive aphasia (svPPA), 46 non-fluent variant PPA (nfvPPA), 49 progressive supranuclear palsy syndrome (PSPS), 44 corticobasal syndrome (CBS)]. The GDS was divided into subscales based on a previously published factor analysis, representing five symptoms (dysphoria, hopelessness, withdrawal, worry, and cognitive concerns). Mixed models were created to examine differences in depression subscale by group, and logistic regression analyses were performed to determine if patterns of depressive symptoms could predict a patient's NDG syndrome. PSPS patients presented with a hopeless, dysphoric, and withdrawn pattern, while patients with CBS presented with a similar but less severe pattern. Worry was a key symptom in the profile of patients with svPPA, while ADs only had abnormally elevated cognitive concerns. Depressive profile accurately predicted NDG diagnosis at a rate of between 70 and 84% accuracy. Conclusions: These results suggest that attention to specific depressive symptom profile can improve diagnostic sensitivity and can be used to provide more individualized patient care.
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Keyword:
2.1 Biological and endogenous factors; 7.3 Management and decision making; Acquired Cognitive Impairment; Aging; Alzheimer's; Alzheimer's Disease; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD); Behavioral and Social Science; Brain Disorders; Clinical Research; Clinical Sciences; Dementia; depression; dysphora; frontotemporal dementia; Frontotemporal Dementia (FTD); hopelessness; Mental Health; Neurodegenerative; neurodegenerative disease; Neurological; Neurosciences; progressive supranuclear palsy; Psychology; Rare Diseases; worry
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URL: https://escholarship.org/uc/item/7d043256
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Amount and delay insensitivity during intertemporal choice in three neurodegenerative diseases reflects dorsomedial prefrontal atrophy.
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Prostate-Specimen Antigen (PSA) Screening and Shared Decision Making Among Deaf and Hearing Male Patients.
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In: Journal of cancer education : the official journal of the American Association for Cancer Education, vol 35, iss 1 (2020)
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Феномен профессионального выгорания современного преподавателя (на примере преподавателей иностранных языков) ... : выпускная квалификационная работа бакалавра ...
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Нилова, Ирина. - : Санкт-Петербургский политехнический университет Петра Великого, 2020
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Data for: Foreign Language Effect in Decision-making: How Foreign Is It? ...
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Data for: Foreign Language Effect in Decision-making: How Foreign Is It? ...
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ПОРЯДОК ВЫНЕСЕНИЯ СУДОМ РЕШЕНИЯ ПО ДЕЛУ ОБ АДМИНИСТРАТИВНОМ ПРАВОНАРУШЕНИИ ... : THE PROCEDURE FOR THE COURT'S DECISION ON THE CASE OF AN ADMINISTRATIVE OFFENCE ...
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FIRE SERVICE INTELLIGENCE: INFORMED STRATEGIES, OPERATIONS, AND TACTICS
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Neutrosophic AHP for the prioritization of requirements for a computerized facial recognition system ...
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Neutrosophic AHP for the prioritization of requirements for a computerized facial recognition system ...
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Neutrosophic AHP for the prioritization of requirements for a computerized facial recognition system ...
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Neutrosophic AHP for the prioritization of requirements for a computerized facial recognition system ...
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Juror appraisals of forensic evidence: Effects of blind proficiency and cross-examination
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In: CSAFE Publications (2020)
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Multi-stage consistency optimization algorithm to decision-making with incomplete probabilistic linguistic preference relation
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