| 1 |
Expressive language development in adolescents with Down syndrome and fragile X syndrome: change over time and the role of family-related factors.
|
|
|
|
In: Journal of neurodevelopmental disorders, vol 12, iss 1 (2020)
|
|
BASE
|
|
Show details
|
|
|
| 2 |
Depressive Symptom Profiles Predict Specific Neurodegenerative Disease Syndromes in Early Stages.
|
|
|
|
BASE
|
|
Show details
|
|
|
| 3 |
Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium.
|
|
|
|
In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020)
|
|
BASE
|
|
Show details
|
|
|
| 4 |
Use of the CDR® plus NACC FTLD in mild FTLD: Data from the ARTFL/LEFFTDS consortium.
|
|
|
|
In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020)
|
|
BASE
|
|
Show details
|
|
|
| 5 |
Depressive Symptom Profiles Predict Specific Neurodegenerative Disease Syndromes in Early Stages.
|
|
|
|
BASE
|
|
Show details
|
|
|
| 6 |
Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium.
|
|
|
|
In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020)
|
|
BASE
|
|
Show details
|
|
|
| 7 |
Use of the CDR® plus NACC FTLD in mild FTLD: Data from the ARTFL/LEFFTDS consortium.
|
|
|
|
In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020)
|
|
BASE
|
|
Show details
|
|
|
| 8 |
A neurophysiological model of speech production deficits in fragile X syndrome.
|
|
|
|
In: Brain communications, vol 2, iss 1 (2020)
|
|
BASE
|
|
Show details
|
|
|
| 9 |
Screen time in 36-month-olds at increased likelihood for ASD and ADHD.
|
|
|
|
BASE
|
|
Show details
|
|
|
| 10 |
Screen time in 36-month-olds at increased likelihood for ASD and ADHD.
|
|
|
|
BASE
|
|
Show details
|
|
|
| 11 |
Molecular Biomarkers Predictive of Sertraline Treatment Response in Young Children With Autism Spectrum Disorder.
|
|
|
|
BASE
|
|
Show details
|
|
|
| 12 |
A Therapeutic Relational Agent for Reducing Problematic Substance Use (Woebot): Development and Usability Study (Preprint)
|
|
|
|
Abstract:
BACKGROUND Misuse of substances is common, can be serious and costly to society, and often goes untreated due to barriers to accessing care. Woebot is a mental health digital solution informed by cognitive behavioral therapy and built upon an artificial intelligence–driven platform to deliver tailored content to users. In a previous 2-week randomized controlled trial, Woebot alleviated depressive symptoms. OBJECTIVE This study aims to adapt Woebot for the treatment of substance use disorders (W-SUDs) and examine its feasibility, acceptability, and preliminary efficacy. METHODS American adults (aged 18-65 years) who screened positive for substance misuse without major health contraindications were recruited from online sources and flyers and enrolled between March 27 and May 6, 2020. In a single-group pre/postdesign, all participants received W-SUDs for 8 weeks. W-SUDs provided mood, craving, and pain tracking and modules (psychoeducational lessons and psychotherapeutic tools) using elements of dialectical behavior therapy and motivational interviewing. Paired samples t tests and McNemar nonparametric tests were used to examine within-subject changes from pre- to posttreatment on measures of substance use, confidence, cravings, mood, and pain. RESULTS The sample (N=101) had a mean age of 36.8 years (SD 10.0), and 75.2% (76/101) of the participants were female, 78.2% (79/101) were non-Hispanic White, and 72.3% (73/101) were employed. Participants’ W-SUDs use averaged 15.7 (SD 14.2) days, 12.1 (SD 8.3) modules, and 600.7 (SD 556.5) sent messages. About 94% (562/598) of all completed psychoeducational lessons were rated positively. From treatment start to end, in-app craving ratings were reduced by half (87/101, 86.1% reporting cravings in the app; odds ratio 0.48, 95% CI 0.32-0.73). Posttreatment assessment completion was 50.5% (51/101), with better retention among those who initially screened higher on substance misuse. From pre- to posttreatment, confidence to resist urges to use substances significantly increased (mean score change +16.9, SD 21.4; P<.001), whereas past month substance use occasions (mean change −9.3, SD 14.1; P<.001) and scores on the Alcohol Use Disorders Identification Test-Concise (mean change −1.3, SD 2.6; P<.001), 10-item Drug Abuse Screening Test (mean change −1.2, SD 2.0; P<.001), Patient Health Questionnaire-8 item (mean change 2.1, SD 5.2; P=.005), Generalized Anxiety Disorder-7 (mean change −2.3, SD 4.7; P=.001), and cravings scale (68.6% vs 47.1% moderate to extreme; P=.01) significantly decreased. Most participants would recommend W-SUDs to a friend (39/51, 76%) and reported receiving the service they desired (41/51, 80%). Fewer felt W-SUDs met most or all of their needs (22/51, 43%). CONCLUSIONS W-SUDs was feasible to deliver, engaging, and acceptable and was associated with significant improvements in substance use, confidence, cravings, depression, and anxiety. Study attrition was high. Future research will evaluate W-SUDs in a randomized controlled trial with a more diverse sample and with the use of greater study retention strategies. CLINICALTRIAL ClinicalTrials.gov NCT04096001; http://clinicaltrials.gov/ct2/show/NCT04096001.
|
|
Keyword:
Behavioral and Social Science; Brain Disorders; Clinical Research; Clinical Trials and Supportive Activities; Mental Health; Neurosciences; Substance Abuse
|
|
URL: https://escholarship.org/uc/item/4q42x0f7
|
|
BASE
|
|
Hide details
|
|
|
| 13 |
The Relationship between Expressive Language Sampling and Clinical Measures in Fragile X Syndrome and Typical Development.
|
|
|
|
In: Brain sciences, vol 10, iss 2 (2020)
|
|
BASE
|
|
Show details
|
|
|
| 14 |
Artificial intelligence approaches to predicting and detecting cognitive decline in older adults: A conceptual review.
|
|
|
|
BASE
|
|
Show details
|
|
|
| 15 |
Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry.
|
|
|
|
In: Molecular psychiatry, vol 25, iss 10 (2020)
|
|
BASE
|
|
Show details
|
|
|
| 16 |
Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry.
|
|
|
|
In: Molecular psychiatry, vol 25, iss 10 (2020)
|
|
BASE
|
|
Show details
|
|
|
| 17 |
Health comorbidities and cognitive abilities across the lifespan in Down syndrome. ...
|
|
|
|
BASE
|
|
Show details
|
|
|
| 18 |
Клинико-лингвистические характеристики психических нарушений при ВИЧ-инфицировании ... : Clinical and linguistic characteristics of mental disorders in HIV infection ...
|
|
|
|
BASE
|
|
Show details
|
|
|
| 19 |
Assessing Health Related Quality of Life, Language Impairment, and Psychosocial Factors in Post-Stroke Aphasia
|
|
|
|
In: Honors College (2020)
|
|
BASE
|
|
Show details
|
|
|
| 20 |
Специфика обследования и коррекции речевых нарушений у пациентки с подкорковой афазией ... : Examination and rehabilitation of speech disorders in a patient with subcortical aphasia ...
|
|
|
|
BASE
|
|
Show details
|
|
|
|
|
