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1
A cross-sectional and longitudinal study on the protective effect of bilingualism against dementia using brain atrophy and cognitive measures
Abstract: Background: Evidence from previous studies suggests that bilingualism contributes to cognitive reserve because bilinguals manifest the first symptoms of Alzheimer's disease (AD) up to 5 years later than monolinguals. Other cross-sectional studies demonstrate that bilinguals show greater amounts of brain atrophy and hypometabolism than monolinguals, despite sharing the same diagnosis and suffering from the same symptoms. However, these studies may be biased by possible pre-existing between-group differences. Methods: In this study, we used global parenchymal measures of atrophy and cognitive tests to investigate the protective effect of bilingualism against dementia cross-sectionally and prospectively, using a sample of bilinguals and monolinguals in the same clinical stage and matched on sociodemographic variables. Results: Our results suggest that the two groups did not differ in their cognitive status at baseline, but bilinguals had less parenchymal volume than monolinguals, especially in areas related to brain atrophy in dementia. In addition, a longitudinal prospective analysis revealed that monolinguals lost more parenchyma and had more cognitive decline than bilinguals in a mean follow-up period of 7 months. Conclusion: These results provide the first prospective evidence that bilingualism may act as a neuroprotective factor against dementia and could be considered a factor in cognitive reserve.
Keyword: Alzheimer's disease; Bilingualism; Bilingüisme; Malaltia d'Alzheimer
URL: http://hdl.handle.net/2445/163857
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2
Bilingual language control : Evidence from Parkinson's disease
Cattaneo, Gabriele, 1984-. - : Universitat Pompeu Fabra, 2017
In: TDX (Tesis Doctorals en Xarxa) (2017)
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3
Labeling, word mapping and categorization in monolingual and bilingual infants
Ibáñez Lillo, Alexandra, 1986-. - : Universitat Pompeu Fabra, 2017
In: TDX (Tesis Doctorals en Xarxa) (2017)
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4
The Effects of foreign-accented speech on language comprehension and retrieval processes
Romero Rivas, Carlos, 1986-. - : Universitat Pompeu Fabra, 2016
In: TDX (Tesis Doctorals en Xarxa) (2016)
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5
The mechanisms and the scope of bilingual language production
Branzi, Francesca Martina, 1984-. - : Universitat Pompeu Fabra, 2014
In: TDX (Tesis Doctorals en Xarxa) (2014)
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6
The impact of early bilingualism on controlling a language learned late: an ERP study
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7
The Bilingual cost in speech production : studies of phonological and articulatory processes
Sadat Schaffai, Jasmin, 1982-. - : Universitat Pompeu Fabra, 2012
In: TDX (Tesis Doctorals en Xarxa) (2012)
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8
The impact of bilingualism on the executive control and orienting networks of attention
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9
Deafness for the meanings of number words
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10
Phonological activation of non-produced words. The dynamics of lexical access in speech production
Navarrete Sánchez, Eduardo. - : Universitat de Barcelona, 2007
In: TDX (Tesis Doctorals en Xarxa) (2007)
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11
Phonological activation of non-produced words. The dynamics of lexical access in speech production
Navarrete Sánchez, Eduardo. - : Universitat de Barcelona, 2007
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12
Psicologia del llenguatge, setembre 2003
Aparici Aznar, Melina; Costa Martínez, Albert; Demestre Viladevall, Josep. - : Universitat Oberta de Catalunya, 2003
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13
Psicologia del llenguatge, setembre 2003
Aparici Aznar, Melina; Costa Martínez, Albert; Demestre Viladevall, Josep. - : Universitat Oberta de Catalunya, 2003
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14
Psicologia del llenguatge, setembre 2003
Aparici Aznar, Melina; Costa Martínez, Albert; Demestre Viladevall, Josep. - : Universitat Oberta de Catalunya, 2003
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15
Psicologia del llenguatge, setembre 2003
Aparici Aznar, Melina; Costa Martínez, Albert; Demestre Viladevall, Josep. - : Universitat Oberta de Catalunya, 2003
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