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Training-related changes of brain activation for speech production in healthy speakers - a longitudinal fMRI study to mimic aphasia therapy
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Determinants of Concurrent Motor and Language Recovery during Intensive Therapy in Chronic Stroke Patients: Four Single-Case Studies.
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Therapy-induced brain reorganization patterns in aphasia
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In: Brain. - 138, 4 (2015) , 1097-1112, ISSN: 1460-2156 (2015)
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The direction of word stress processing in German: evidence from a working memory paradigm
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Paving the Way for Speech: Voice-Training-Induced Plasticity in Chronic Aphasia and Apraxia of Speech—Three Single Cases
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The neural correlates of agrammatism: Evidence from aphasic and healthy speakers performing an overt picture description task
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The Role of Human Parietal Area 7A as a Link between Sequencing in Hand Actions and in Overt Speech Production ...
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Enhancement and suppression in a lexical interference fMRI-paradigm ...
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The Role of Human Parietal Area 7A as a Link between Sequencing in Hand Actions and in Overt Speech Production
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Enhancement and suppression in a lexical interference fMRI-paradigm
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Enhancement and suppression in a lexical interference fMRI-paradigm: Mechanisms of Lexical Interference
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In: Brain and Behavior. - 2, 2 (2012) , 109-127, ISSN: 2162-3279 (2012)
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Task-dependent Modulations of Prefrontal and Hippocampal Activity during Intrinsic Word Production
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Abstract:
Functional imaging studies of single word production have consistently reported activation of the lateral prefrontal and cingulate cortex. Its contribution has been shown to be sensitive to task demands, which can be manipulated by the degree of response specification. Compared with classical verbal fluency, free word association relies less on response restrictions but to a greater extent on associative binding processes, usually subserved by the hippocampus. To elucidate the relevance of the frontal and medial-temporal areas during verbal retrieval tasks, we applied varying degrees of response specification. During fMRI data acquisition, 18 subjects performed a free verbal association (FVA), a semantic verbal fluency (SVF) task, and a phonological verbal fluency (PVF) task. Externally guided word production served as a baseline condition to control for basic articulatory and reading processes. As expected, increased brain activity was observed in the left lateral and bilateral medial frontal cortices for SVF and PVF. The anterior cingulate gyrus was the only structure common to both fluency tasks in direct comparison to the less restricted FVA task. The hippocampus was engaged during associative and semantic retrieval. Interestingly, hippocampal activity was selectively evident during FVA in direct comparison to SVF when it was controlled for stimulus–response relations. The current data confirm the role of the left prefrontal–cingulate network in constrained word production. Hippocampal activity during spontaneous word production is a novel finding and seems to be dependent on the retrieval process (free vs. constrained) rather than the variety of stimulus–response relationships that is involved.
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URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761015 https://doi.org/10.1162/jocn.2009.21056 http://www.ncbi.nlm.nih.gov/pubmed/18578599
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The separation of processing stages in a lexical interference fMRI-paradigm
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In: NeuroImage. - 44, 3 (2009) , 1113-1124, ISSN: 1053-8119 (2008)
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Deep dysphasia as a phonetic input deficit: Evidence from a single case
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In: Aphasiology. - 22, 5 (2008) , 537-556, ISSN: 0268-7038 (2008)
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Supervised Home Training in Aphasia: Application of the Electronic Language Trainer B.A.Bar - A Single Case Study.
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Measuring change in spontaneous speech production during the course of aphasia: Computer-assisted analysis of basic parameters
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Recovery of semantic word processing in global aphasia: a functional MRI study
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In: Cognitive Brain Research. - 18, 3 (2004) , 322-336, ISSN: 0926-6410 (2004)
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Lexical decision of nonwords and pseudowords in humans: a positron emission tomography study
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In: Neuroscience Letters. - 345, 3 (2003) , 177-181, ISSN: 0304-3940 (2003)
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