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Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0.
In: Nature protocols, vol 14, iss 3 (2019)
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Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0.
In: Nature protocols, vol 14, iss 3 (2019)
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Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0
Heirendt, Laurent; Arreckx, Sylvain; Pfau, Thomas. - : Springer Nature, 2019
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Creation and analysis of biochemical constraint-based models: the COBRA Toolbox v3.0
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Creation and analysis of biochemical constraint-based models: the COBRA Toolbox v3.0 ...
Abstract: COnstraint-Based Reconstruction and Analysis (COBRA) provides a molecular mechanistic framework for integrative analysis of experimental data and quantitative prediction of physicochemically and biochemically feasible phenotypic states. The COBRA Toolbox is a comprehensive software suite of interoperable COBRA methods. It has found widespread applications in biology, biomedicine, and biotechnology because its functions can be flexibly combined to implement tailored COBRA protocols for any biochemical network. Version 3.0 includes new methods for quality controlled reconstruction, modelling, topological analysis, strain and experimental design, network visualisation as well as network integration of chemoinformatic, metabolomic, transcriptomic, proteomic, and thermochemical data. New multi-lingual code integration also enables an expansion in COBRA application scope via high-precision, high-performance, and nonlinear numerical optimisation solvers for multi-scale, multi-cellular and reaction kinetic ...
Keyword: FOS Biological sciences; Quantitative Methods q-bio.QM
URL: https://arxiv.org/abs/1710.04038
https://dx.doi.org/10.48550/arxiv.1710.04038
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