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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 1 of 1 1 The influence of dopamine on semantic activation in Parkinson's disease: Evidence from a multipriming task Angwin, A. J.; Copland, D. A.; Chenery, H. J.; Murdoch, B. E.; Silburn, P. A.. - : American Psychological Association, 2006 Abstract: Research has suggested that semantic processing deficits in Parkinson's disease (PD) are related to striatal dopamine deficiency. As an investigation of the influence of dopamine on semantic activation in PD, 7 participants with PD performed a lexical-decision task when on and off levodopa medication. Seven healthy controls matched to the participants with PD in terms of sex, age, and education also participated in the study. By use of a multipriming paradigm, whereby 2 prime words were presented prior to the target word, semantic priming effects were measured across stimulus onset asynchronies (SOAs) of 250 Ins and 1,200 Ins. The results revealed a similar pattern of priming across SOAs for the control group and the PD participants on medication. In contrast, within-group comparisons revealed that automatic semantic activation was compromised in PD participants when off medication. The implications of these results for the neuromodulatory influence of dopamine on semantic processing in PD are discussed. Keyword: 380302 Linguistic Processes (incl. Speech Production and Comprehension); 730111 Hearing; Attention; Basal Ganglia; C1; Clinical; Cognitive Impairments; Dopamine; Individuals; Inhibition; Levodopa; Memory; Modulation; Neurosciences; Parkinson's Disease; Psychology; Schizophrenic-patients; Semantic Priming; Sentence Comprehension; Signal-to-noise Ratio; speech and their disorders; Summation; vision URL: https://espace.library.uq.edu.au/view/UQ:81555 BASE Hide details

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