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Does Cue Focality Modulate Age-related Performance in Prospective Memory? An fMRI Investigation
Abstract: How prospective memory (PM) weakens with increasing age has been largely debated. We hypothesized that automatic and strategic PM processes, respectively mediated by focal and non-focal cues, are differently affected by aging, even starting from 50-60 years of age. We investigated this issue using a 2 x 2 design in which focal and non-focal experimental conditions were created by varying the conjoint nature of the ongoing task (lexical decision vs. syllable matching tasks) and the PM cue (words vs. syllables). In the whole-brain analysis we found that the left inferior frontal gyrus and the middle cingulate cortex were more activated when young compared to older individuals performed a PM task; moreover, the anterior cingulate cortex was selectively activated during non-focal PM when the cues were words. In a region-of-interest analysis we observed that the medial and the lateral portions of the rostral prefrontal cortex were associated with the focal and non-focal conditions respectively, more in young than in older adults. Our findings provide evidence in support of early age-related differences in automatic/strategic PM functioning.
Keyword: Settore MED/26
URL: http://hdl.handle.net/2108/274839
https://doi.org/10.1080/0361073X.2020.1839310
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2
Effects of palmitoylethanolamide combined with luteoline on frontal lobe functions, high frequency oscillations, and GABAergic transmission in patients with frontotemporal dementia
Assogna, M; Paolo Casula, E; Borghi, I. - : country:GB, 2020
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3
Associative agreement as a predictor of naming ability in alzheimer’s disease: A case for the semantic nature of associative links
Zannino, GD; Perri, R; Teghil, A. - : FRONTIERS MEDIA SA, 2018
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4
Transcranial cerebellar direct current stimulation enhances verb generation but not verb naming in poststroke Aphasia
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5
Moving beyond the brain: Transcutaneous spinal direct current stimulation in post-stroke aphasia
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6
Does dopamine depletion trigger a spreader lexical-semantic activation in Parkinson’s disease? Evidence from a study based on word fluency tasks.
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7
Right sensory-motor functional networks subserve action observation therapy in aphasia
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8
Bilateral transcranial direct current stimulation language treatment enhances functional connectivity in the left hemisphere: Preliminary data from aphasia
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9
Combining TMS-EEG with transcranial direct current stimulation language treatment in aphasia
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10
Processing past tense in the left cerebellum
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11
Bihemispheric tDCS enhances language recovery but does not alter BDNF levels in chronic aphasic patients
Fiori, V; Caltagirone, C; Marangolo, P. - : IOS Press, 2014
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12
Forward and backward span for verbal and visuo-spatial data: standardization and normative data from an Italian adult population
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13
tDCS over the left inferior frontal cortex improves speech production in aphasia
Razzano, C; Campana, S; Marangolo, P. - : Frontiers Research Foundation, 2013
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14
Options to enhance recovery from aphasia by means of non-invasive brain stimulation and action observation therapy
Caltagirone, C; Marangolo, P. - : Expert Reviews Ltd, 2013
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15
Something to talk about: Enhancement of linguistic cohesion through tdCS in chronic non fluent aphasia
Marangolo, P; Fiori, V; Campana, S. - : Elsevier Science Limited, 2013
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16
tDCS stimulation segregates words in the brain: evidence from aphasia
Razzano, C; Cipollari, S; Marangolo, P. - : Frontiers Research Foundation, 2013
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17
Bihemispheric stimulation over left and right inferior frontal region enhances recovery from apraxia of speech in chronic aphasia
Cipollari, S; Campana, S; Marangolo, P. - : Wiley-Blackwell, 2013
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18
High frequency rTMS over the left parietal lobule increases non-word reading accuracy
Costanzo, F; Menghini, D; Caltagirone, C. - : Elsevier Science Limited, 2012
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19
Walking but not barking improves verb recovery: implications for action observation treatment in aphasia rehabilitation
Marangolo, P; Cipollari, S; Fiori, V. - : Public Library of Science, 2012
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20
Forward and backward span for verbal and visuo-spatial data: standardization and normative data from an Italian adult population
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