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1
Diminished preparatory physiological responses in frontotemporal lobar degeneration syndromes
In: Brain Commun (2022)
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2
Uniform data set language measures for bvFTD and PPA diagnosis and monitoring
In: Alzheimers Dement (Amst) (2021)
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3
Depressive Symptom Profiles Predict Specific Neurodegenerative Disease Syndromes in Early Stages
In: Front Neurol (2020)
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4
Visuospatial Functioning In The Primary Progressive Aphasias
Watson, Christa L.; Possin, Katherine; Allen, I. Elaine. - : Cambridge Univ Press, 2018
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5
Reading words and other people: a comparison of exception word, familiar face and affect processing in the left and right temporal variants of primary progressive aphasia
Abstract: Semantic variant primary progressive aphasia (svPPA) typically presents with left-hemisphere predominant rostral temporal lobe atrophy and the most significant complaints within the language domain. Less frequently, patients present with right-hemisphere predominant temporal atrophy coupled with marked impairments in processing of famous faces and emotions. Few studies have objectively compared these patient groups in both domains and therefore it is unclear to what extent the syndromes overlap. Clinically diagnosed svPPA patients were characterized as left- (n= 21) or right-predominant (n = 12) using imaging and compared along with 14 healthy controls. Regarding language, our primary focus was upon two hallmark features of svPPA; confrontation naming and surface dyslexia. Both groups exhibited naming deficits and surface dyslexia although the impairments were more severe in the left-predominant group. Familiarity judgments on famous faces and affect processing were more profoundly impaired in the right-predominant group. Our findings suggest that the two syndromes overlap significantly but that early cases at the tail ends of the continuum constitute a challenge for current clinical criteria. Correlational neuroimaging analyses implicated a mid portion of the left lateral temporal lobe in exception word reading impairments in line with proposals that this region is an interface between phonology and semantic knowledge.
Keyword: Article
URL: https://doi.org/10.1016/j.cortex.2016.05.014
http://www.ncbi.nlm.nih.gov/pubmed/27389800
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969161/
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6
Different regional patterns of cortical thinning in Alzheimer's disease and frontotemporal dementia
In: Brain. - Oxford : Oxford Univ. Press 130 (2007) 4, 1159-1166
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7
The anatomy of category-specific object naming in neurodegenerative diseases
In: Journal of cognitive neuroscience. - Cambridge, Mass. : MIT Press Journals 18 (2006) 10, 1644-1653
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8
Cognition and Anatomy in Three Variants of Primary Progressive Aphasia
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