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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 19 of 19 1 Uniform data set language measures for bvFTD and PPA diagnosis and monitoring Staffaroni, Adam M.; Weintraub, Sandra; Rascovsky, Katya... In: Alzheimers Dement (Amst) (2021) BASE Show details 2 Visuospatial Functioning In The Primary Progressive Aphasias Watson, Christa L.; Possin, Katherine; Allen, I. Elaine. - : Cambridge Univ Press, 2018 BASE Show details 3 Visuospatial Functioning in the Primary Progressive Aphasias Watson, Christa L.; Possin, Katherine; Allen, I. Elaine. - 2017 BASE Show details 4 Emotion detection deficits and changes in personality traits linked to loss of white matter integrity in primary progressive aphasia Multani, Namita; Galantucci, Sebastiano; Wilson, Stephen M.. - : Elsevier, 2017 BASE Show details 5 Reading words and other people: a comparison of exception word, familiar face and affect processing in the left and right temporal variants of primary progressive aphasia Binney, Richard J.; Henry, Maya L.; Babiak, Miranda. - 2016 BASE Show details 6 Handedness and language learning disability differentially distribute in progressive aphasia variants Miller, Zachary A.; Mandelli, Maria Luisa; Rankin, Katherine P.; Henry, Maya L.; Babiak, Miranda C.; Frazier, Darvis T.; Lobach, Iryna V.; Bettcher, Brianne M.; Wu, Teresa Q.; Rabinovici, Gil D.; Graff-Radford, Neill R.; Miller, Bruce L.; Gorno-Tempini, Maria Luisa. - : Oxford University Press, 2013 Abstract: Primary progressive aphasia is a neurodegenerative clinical syndrome that presents in adulthood with an isolated, progressive language disorder. Three main clinical/anatomical variants have been described, each associated with distinctive pathology. A high frequency of neurodevelopmental learning disability in primary progressive aphasia has been reported. Because the disorder is heterogeneous with different patterns of cognitive, anatomical and biological involvement, we sought to identify whether learning disability had a predilection for one or more of the primary progressive aphasia subtypes. We screened the University of California San Francisco Memory and Aging Center's primary progressive aphasia cohort (n = 198) for history of language-related learning disability as well as hand preference, which has associations with learning disability. The study included logopenic (n = 48), non-fluent (n = 54) and semantic (n = 96) variant primary progressive aphasias. We investigated whether the presence of learning disability or non-right-handedness was associated with differential effects on demographic, neuropsychological and neuroimaging features of primary progressive aphasia. We showed that a high frequency of learning disability was present only in the logopenic group (χ2 = 15.17, P < 0.001) and (χ2 = 11.51, P < 0.001) compared with semantic and non-fluent populations. In this group, learning disability was associated with earlier onset of disease, more isolated language symptoms, and more focal pattern of left posterior temporoparietal atrophy. Non-right-handedness was instead over-represented in the semantic group, at nearly twice the prevalence of the general population (χ2 = 6.34, P = 0.01). Within semantic variant primary progressive aphasia the right-handed and non-right-handed cohorts appeared homogeneous on imaging, cognitive profile, and structural analysis of brain symmetry. Lastly, the non-fluent group showed no increase in learning disability or non-right-handedness. Logopenic variant primary progressive aphasia and developmental dyslexia both manifest with phonological disturbances and posterior temporal involvement. Learning disability might confer vulnerability of this network to early-onset, focal Alzheimer’s pathology. Left-handedness has been described as a proxy for atypical brain hemispheric lateralization. As non-right-handedness was increased only in the semantic group, anomalous lateralization mechanisms might instead be related to frontotemporal lobar degeneration with abnormal TARDBP. Taken together, this study suggests that neurodevelopmental signatures impart differential trajectories towards neurodegenerative disease. Keyword: Original Articles URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808687 https://doi.org/10.1093/brain/awt242 http://www.ncbi.nlm.nih.gov/pubmed/24056533 BASE Hide details 7 Anterior temporal lobe degeneration produces widespread network-driven dysfunction Guo, Christine C.; Gorno-Tempini, Maria Luisa; Gesierich, Benno. - : Oxford University Press, 2013 BASE Show details 8 Neuropsychological, behavioral, and anatomical evolution in right temporal variant frontotemporal dementia: A longitudinal and post-mortem single case analysis Henry, Maya L.; Wilson, Stephen M.; Ogar, Jennifer M.. - 2012 BASE Show details 9 Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia Rascovsky, Katya; Hodges, John R.; Knopman, David. - : Oxford University Press, 2011 BASE Show details 10 Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia Rascovsky, Katya; Hodges, John R.; Knopman, David. - : Oxford University Press, 2011 BASE Show details 11 Behavioral-variant frontotemporal dementia with corticobasal degeneration pathology: Phenotypic comparison to bvFTD with Pick’s disease Rankin, Katherine P.; Mayo, Mary Catherine; Seeley, William W.. - 2011 BASE Show details 12 Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia Rascovsky, Katya; Hodges, John R.; Knopman, David. - : Oxford University Press, 2011 BASE Show details 13 Neuropsychological, Behavioral, and Anatomical Evolution in Right Temporal Variant Frontotemporal Dementia: A Longitudinal Single Case Analysis Henry, Maya L.; Cattaruzza, Tatiana; Wilson, Stephen M.. - 2010 BASE Show details 14 Detecting Sarcasm from Paralinguistic Cues: Anatomic and Cognitive Correlates in Neurodegenerative Disease Rankin, Katherine P.; Salazar, Andrea; Gorno-Tempini, Maria Luisa. - 2009 BASE Show details 15 Different regional patterns of cortical thinning in Alzheimer's disease and frontotemporal dementia Du, An-Tao; Schuff, Norbert; Kramer, Joel H.... In: Brain. - Oxford : Oxford Univ. Press 130 (2007) 4, 1159-1166 BLLDB Show details 16 The anatomy of category-specific object naming in neurodegenerative diseases Rosen, Howard J.; Rankin, Katherine P.; Brambati, Simona M.... In: Journal of cognitive neuroscience. - Cambridge, Mass. : MIT Press Journals 18 (2006) 10, 1644-1653 BLLDB OLC Linguistik Show details 17 Anatomical correlates of early mutism in progressive nonfluent aphasia Gorno-Tempini, Maria Luisa; Ogar, Jennifer M.; Brambati, Simona Maria. - : American Academy of Neurology, 2006 BASE Show details 18 Cognition and Anatomy in Three Variants of Primary Progressive Aphasia Gorno-Tempini, Maria Luisa; Dronkers, Nina F.; Rankin, Katherine P.. - 2004 BASE Show details 19 Clinical, Cognitive and Anatomical Evolution from Nonfluent Progressive Aphasia to Corticobasal Syndrome: A Case Report Gorno-Tempini, Maria Luisa; Murray, Ryan C.; Rankin, Katherine P.. - 2004 BASE Show details

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