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Neuroplasticity of language networks in aphasia: advances, updates, and future challenges
Abstract: Researchers have sought to understand how language is processed in the brain, how brain damage affects language abilities, and what can be expected during the recovery period since the early 19th century. In this review, we first discuss mechanisms of damage and plasticity in the post-stroke brain, both in the acute and the chronic phase of recovery. We then review factors that are associated with recovery. First, we review organism intrinsic variables such as age, lesion volume and location and structural integrity that influence language recovery. Next, we review organism extrinsic factors such as treatment that influence language recovery. Here, we discuss recent advances in our understanding of language recovery and highlight recent work that emphasizes a network perspective of language recovery. Finally, we propose our interpretation of the principles of neuroplasticity, originally proposed by Kleim and Jones (1) in the context of extant literature in aphasia recovery and rehabilitation. Ultimately, we encourage researchers to propose sophisticated intervention studies that bring us closer to the goal of providing precision treatment for patients with aphasia and a better understanding of the neural mechanisms that underlie successful neuroplasticity. ; P50 DC012283 - NIDCD NIH HHS ; Published version
Keyword: Aphasia; Clinical sciences; Neuroimaging (anatomic and functional); Neurosciences; Plasticity; Psychology; Recovery; Stroke
URL: https://doi.org/10.3389/fneur.2019.00295
https://www.ncbi.nlm.nih.gov/pubmed/31001187
https://hdl.handle.net/2144/39302
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2
Neurocognitive Recovery of Sentence Processing in Aphasia
Thompson, Cynthia K.. - : American Speech-Language-Hearing Association, 2019
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3
Right hemisphere grey matter volume and language functions in stroke aphasia
Lukic, Sladjana; Barbieri, Elena; Wang, Xue. - : Hindawi Publishing Corporation, 2017
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4
Neuroimaging in aphasia treatment research: quantifying brain lesions after stroke
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5
Neuroimaging in aphasia treatment research: Consensus and practical guidelines for data analysis
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6
Neuroimaging in aphasia treatment research: Standards for establishing the effects of treatment
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7
Tracking passive sentence comprehension in agrammatic aphasia
In: Journal of neurolinguistics. - Orlando, Fla. : Elsevier 25 (2012) 1, 31-43
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8
Dissociations between fluency and agrammatism in primary progressive aphasia
In: Aphasiology. - London [u.a.] : Routledge, Taylor & Francis Group 26 (2012) 1, 20-43
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9
Verb and noun deficits in stroke-induced and primary progressive aphasia: the "Northwestern Naming Battery"
In: Aphasiology. - London [u.a.] : Routledge, Taylor & Francis Group 26 (2012) 5, 632-655
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10
Verb and sentence production and comprehension in aphasia: Northwestern Assessment of Verbs and Sentences (NAVS)
In: Aphasiology. - London [u.a.] : Routledge, Taylor & Francis Group 26 (2012) 10, 1250-1277
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11
Semantic interference during object naming in agrammatic and logopenic primary progressive aphasia (PPA)
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 120 (2012) 3, 237-250
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12
Time reference in agrammatic aphasia: a cross-linguistic study
In: Journal of neurolinguistics. - Orlando, Fla. : Elsevier 24 (2011) 6, 652-673
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13
Real-time production of unergative and unaccusative sentences in normal and agrammatic speakers: an eyetracking study
In: Aphasiology. - London [u.a.] : Routledge, Taylor & Francis Group 25 (2011) 6-7, 813-825
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14
Real-time production of arguments and adjuncts in normal and agrammatic speakers
In: Language and cognitive processes. - Abingdon : Routledge, Taylor & Francis Group 26 (2011) 8, 985-1021
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15
The use of the picture-word interference paradigm to examine naming abilities in aphasic individuals
In: Aphasiology. - London [u.a.] : Routledge, Taylor & Francis Group 24 (2010) 5, 580-611
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16
Binding in agrammatic aphasia: processing to comprehension
In: Aphasiology. - London [u.a.] : Routledge, Taylor & Francis Group 24 (2010) 5, 551-579
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17
What goes wrong during passive sentence production in agrammatic aphasia: an eyetracking study
In: Aphasiology. - London [u.a.] : Routledge, Taylor & Francis Group 24 (2010) 12, 1576-1592
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18
Sentactics: computer-automated treatment of underlying forms
In: Aphasiology. - London [u.a.] : Routledge, Taylor & Francis Group 24 (2010) 10, 1242-1266
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19
Neural mechanisms of verb argument structure processing in agrammatic aphasic and healthy age-matched listeners
In: Journal of cognitive neuroscience. - Cambridge, Mass. : MIT Press Journals 22 (2010) 9, 1993-2011
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20
Production latencies of morphologically simple and complex verbs in aphasia
In: Clinical linguistics & phonetics. - London : Informa Healthcare 24 (2010) 12, 963-979
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