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1
Global familiarity of visual stimuli affects repetition-related neural plasticity but not repetition priming
Abstract: In this study we tested the prediction of the component process model of priming (Henson, 2003) that repetition priming of familiar and unfamiliar objects produces qualitatively different neural repetition effects. In an fMRI study, subjects viewed four repetitions of familiar objects and globally unfamiliar objects with familiar components. Reliable behavioral priming occurred for both item types across the four presentations and was of a similar magnitude for both stimulus types. The imaging data was analyzed using multivariate linear modeling, which permits explicit testing of the hypothesis that the repetition effects for familiar and unfamiliar objects are qualitatively different (i.e., non-scaled versions of one another). The results showed the presence of two qualitatively different latent spatial patterns of repetition effects from presenation one to presentation four for familiar and unfamilar objects, indicating that familiarity with an object’s global structural, semantic, or lexical features is an important factor in priming-related neural plasticity. The first latent spatial pattern strongly weighted regions with a similar repetition effect for both item types. The second pattern strongly weighted regions contributing a repetition suppression effect for the familiar objects and repetition enhancement for the unfamiliar objects, particularly the posterior insula, superior temporal gyrus, precentral gyrus, and cingulate cortex. This differential repetition effect might reflect the formation of novel memory representations for the unfamiliar items, which already exist for the familiar objects, consistent with the component-process model of priming.
Keyword: Article
URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140238
https://doi.org/10.1016/j.neuroimage.2007.08.011
http://www.ncbi.nlm.nih.gov/pubmed/17913513
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2
Identification and Differential Vulnerability of a Neural Network in Sleep Deprivation
Bell-McGinty, Sandra; Habeck, Christian; Hilton, H. John. - : Oxford University Press, 2004
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3
Positive Evidence against Human Hippocampal Involvement in Working Memory Maintenance of Familiar Stimuli
Zarahn, Eric; Rakitin, Brian; Abela, Diane. - : Oxford University Press, 2004
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4
Positive Evidence against Human Hippocampal Involvement in Working Memory Maintenance of Familiar Stimuli
Zarahn, Eric; Rakitin, Brian; Abela, Diane. - : Oxford University Press, 2004
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