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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 5 of 5 1 The speed of lexical activation is altered in Parkinson's disease Angwin, Anthony J.; Chenery, Helen J.; Copland, David A.; Murdoch, Bruce E.; Silburn, Peter A.. - : Taylor & Francis Inc, 2007 Abstract: Disturbed comprehension of complex noncanonical sentences in Parkinson's disease (PD) has been linked to dopamine depletion and delayed lexical retrieval. The aim of the present study was to replicate findings of delayed lexical activation in PD patients with noncanonical sentence processing difficulties, and investigate the influence of dopamine depletion on these changes to lexical access. In the first experiment, 20 patients with PD (tested whilst 'on' dopaminergic medication) and 23 controls participated in a list priming experiment. In this paradigm, stimuli are presented as a continuous list of words/nonwords, and semantic priming effects were measured across inter-stimulus intervals (ISIs) of 500 ms, 1000 ms and 1500 ms, with data analyzed using multivariate analyses of variance. The results revealed longer delays in lexical activation for PD patients with poor comprehension of noncanonical sentences, suggesting that the speed of lexical access may be compromised in PD, and that this feature may contribute to certain sentencecomprehension difficulties. In the second experiment, 7 patients with PD who participated in the first experiment, performed the same lexical decision task while 'off' their dopaminergic medication. Semantic priming effects were measured across ISIs of 500 ms and 1500 ms. Within group comparisons revealed a different pattern of semantic priming for the PD patients when 'on' compared to 'off' medication, providing further support for a dopaminergic influence on the speed of information processing and lexical activation. Keyword: 380102 Learning; 380302 Linguistic Processes (incl. Speech Production and Comprehension); 730303 Occupational; Aphasia; Basal Ganglia; C1; Clinical; Clinical Neurology; Cognition and Language; Constructions; Dopaminergic Modulation; Fmri; Memory; Processing Speed; Psychology; Resource; Semantic Activation; speech and physiotherapy; Supports Sentence Comprehension; Time-course URL: https://espace.library.uq.edu.au/view/UQ:127625 BASE Hide details 2 Beyond verbal fluency: Investigating the long-term effects of bilateral subthalamic (STN) deep brain stimulation (DBS) on language in two cases Murdoch, Bruce E.; Theodoros, Deborah G.; Hall, Bruce. - : Routledge Taylor & Francis Ltd, 2005 BASE Show details 3 Semantic priming in Parkinson's disease: Evidence for delayed spreading activation Arnott, Wendy L.; Chenery, Helen J.; Murdoch, Bruce E.. - : Psychology Press, 2001 BASE Show details 4 Discourse priming of homophones in individuals with dominant subcortical lesions, cortical lesions, and Parkinson’s disease Copland, David A.; Chenery, Helen J.; Murdoch, Bruce E.. - : Psychology Press, 2001 BASE Show details 5 The use of a miniature lip transducer system in the assessment of patients with Parkinsons disease Thompson-Ward, Elizabeth C.; Theodoros, Deborah G.; Murdoch, Bruce E.. - : Singular, 1999 BASE Show details

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