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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 5 of 5 1 Age-related Changes in Tissue Signal Properties Within Cortical Areas Important for Word Understanding in 12- to 19-Month-Old Infants Travis, Katherine E.; Curran, Megan M.; Torres, Christina; Leonard, Matthew K.; Brown, Timothy T.; Dale, Anders M.; Elman, Jeffrey L.; Halgren, Eric. - : Oxford University Press, 2013 Abstract: Recently, our laboratory has shown that the neural mechanisms for encoding lexico-semantic information in adults operate functionally by 12–18 months of age within left frontotemporal cortices (Travis et al., 2011. Spatiotemporal neural dynamics of word understanding in 12- to 18-month-old-infants. Cereb Cortex. 8:1832–1839). However, there is minimal knowledge of the structural changes that occur within these and other cortical regions important for language development. To identify regional structural changes taking place during this important period in infant development, we examined age-related changes in tissue signal properties of gray matter (GM) and white matter (WM) intensity and contrast. T 1 -weighted surface-based measures were acquired from 12- to 19-month-old infants and analyzed using a general linear model. Significant age effects were observed for GM and WM intensity and contrast within bilateral inferior lateral and anterovental temporal regions, dorsomedial frontal, and superior parietal cortices. Region of interest (ROI) analyses revealed that GM and WM intensity and contrast significantly increased with age within the same left lateral temporal regions shown to generate lexico-semantic activity in infants and adults. These findings suggest that neurophysiological processes supporting linguistic and cognitive behaviors may develop before cellular and structural maturation is complete within associative cortices. These results have important implications for understanding the neurobiological mechanisms relating structural to functional brain development. Keyword: Article URL: https://doi.org/10.1093/cercor/bht052 http://cercor.oxfordjournals.org/cgi/content/short/bht052v1 BASE Hide details 2 White Matter Microstructure Correlates of Narrative Production in Typically Developing Children and Children with High Functioning Autism Mills, Brian; Lai, Janie; Brown, Timothy T.. - 2013 BASE Show details 3 Spatiotemporal Neural Dynamics of Word Understanding in 12- to 18-Month-Old-Infants Travis, Katherine E.; Leonard, Matthew K.; Brown, Timothy T.. - : Oxford University Press, 2011 BASE Show details 4 Spatiotemporal Dynamics of Bilingual Word Processing Leonard, Matthew K.; Brown, Timothy T.; Travis, Katherine E.. - 2009 BASE Show details 5 Developmental Changes in Human Cerebral Functional Organization for Word Generation Brown, Timothy T.; Lugar, Heather M.; Coalson, Rebecca S.. - : Oxford University Press, 2004 BASE Show details

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