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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 3 of 3 1 Structural and Functional Reorganization of the Corpus Callosum between the Age of 6 and 8 Years Westerhausen, René; Luders, Eileen; Specht, Karsten. - : Oxford University Press, 2011 BASE Show details 2 Structural and Functional Reorganization of the Corpus Callosum between the Age of 6 and 8 Years Westerhausen, René; Luders, Eileen; Specht, Karsten. - : Oxford University Press, 2011 BASE Show details 3 Mapping Cortical Thickness in Children with 22q11.2 Deletions Bearden, Carrie E.; van Erp, Theo G.M.; Dutton, Rebecca A.; Tran, Helen; Zimmermann, Lara; Sun, Daqiang; Geaga, Jennifer A.; Simon, Tony J.; Glahn, David C.; Cannon, Tyrone D.; Emanuel, Beverly S.; Toga, Arthur W.; Thompson, Paul M.. - : Oxford University Press, 2007 Abstract: The 22q11.2 deletion syndrome (velocardiofacial/DiGeorge syndrome, 22q11.2DS) involves cardiac and craniofacial anomalies, marked deficits in visuospatial cognition, and elevated rates of psychosis. Although the mechanism is unknown, characteristic brain alterations may predispose to development of psychosis and cognitive deficits in 22q11DS. We applied cortical pattern matching and new methods for measuring cortical thickness in millimeters to structural magnetic resonance images of 21 children with confirmed 22q11.2 deletions and 13 demographically matched healthy comparison subjects. Thickness was mapped at 65 536 homologous points, based on 3-dimensional distance from the cortical gray–white matter interface to the external gray–cerebrospinal fluid boundary. A pattern of regionally specific cortical thinning was observed in superior parietal cortices and right parietooccipital cortex, regions critical for visuospatial processing, and bilaterally in the most inferior portion of the inferior frontal gyrus (pars orbitalis), a key area for language development. Several of the 30 genes encoded in the deleted segment are highly expressed in the developing brain and known to affect early neuronal migration. These brain maps reveal how haploinsufficiency for such genes can affect cortical development and suggest a possible underlying pathophysiology of the neurobehavioral phenotype. Keyword: Articles URL: https://doi.org/10.1093/cercor/bhl097 http://cercor.oxfordjournals.org/cgi/content/short/17/8/1889 BASE Hide details

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