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Open access dataset of task-free hemodynamic activity in 4-month-old infants during sleep using fNIRS. ...
Blanco, Borja; Molnar, Monika; Carreiras, Manuel. - : Apollo - University of Cambridge Repository, 2022
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2
Resting functional connectivity in the semantic appraisal network predicts accuracy of emotion identification.
Yang, Winson FZ; Toller, Gianina; Shdo, Suzanne. - : eScholarship, University of California, 2021
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Resting functional connectivity in the semantic appraisal network predicts accuracy of emotion identification.
Abstract: ObjectiveStructural and task-based functional studies associate emotion reading with frontotemporal brain networks, though it remains unclear whether functional connectivity (FC) alone predicts emotion reading ability. The predominantly frontotemporal salience and semantic appraisal (SAN) networks are selectively impacted in neurodegenerative disease syndromes like behavioral-variant frontotemporal dementia (bvFTD) and semantic-variant primary progressive aphasia (svPPA). Accurate emotion identification diminishes in some of these patients, but studies investigating the source of this symptom in patients have predominantly examined structural rather than functional brain changes. Thus, we investigated the impact of altered connectivity on their emotion reading.MethodsOne-hundred-eighty-five participants (26 bvFTD, 21 svPPA, 24 non-fluent variant PPA, 24 progressive supranuclear palsy, 49 Alzheimer's disease, 41 neurologically healthy older controls) underwent task-free fMRI, and completed the Emotion Evaluation subtest of The Awareness of Social Inference Test (TASIT-EET), watching videos and selecting labels for actors' emotions.ResultsAs expected, patients averaged significantly worse on emotion reading, but with wide inter-individual variability. Across all groups, lower mean FC in the SAN, but not other ICNs, predicted worse TASIT-EET performance. Node-pair analysis revealed that emotion identification was predicted by FC between 1) right anterior temporal lobe (RaTL) and right anterior orbitofrontal (OFC), 2) RaTL and right posterior OFC, and 3) left basolateral amygdala and left posterior OFC.ConclusionEmotion reading test performance predicts FC in specific SAN regions mediating socioemotional semantics, personalized evaluations, and salience-driven attention, highlighting the value of emotion testing in clinical and research settings to index neural circuit dysfunction in patients with neurodegeneration and other neurologic disorders.
Keyword: 2.1 Biological and endogenous factors; Acquired Cognitive Impairment; Aging; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD); Aphasia; Basic Behavioral and Social Science; Behavioral and Social Science; Brain; Brain Disorders; Clinical Research; Dementia; Emotion reading; Emotions; Frontotemporal Dementia; Frontotemporal Dementia (FTD); Functional connectivity; Humans; Magnetic Resonance Imaging; Neurodegeneration; Neurodegenerative; Neurodegenerative Diseases; Neurological; Neurosciences; Primary Progressive; Right anterior temporal lobe; Semantic appraisal network; Semantics
URL: https://escholarship.org/uc/item/67m8f14f
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4
A Bayesian optimization approach for rapidly mapping residual network function in stroke. ...
Lorenz, Romy; Johal, Michelle; Dick, Frederic. - : Apollo - University of Cambridge Repository, 2021
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5
Age-related differences in the neural bases of phonological and semantic processes.
Burke, Deborah M; Diaz, Michele T; Madden, David J. - : MIT Press - Journals, 2021
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Age-related differences in resolving semantic and phonological competition during receptive language tasks.
Madden, David J; Johnson, Micah A; Zhuang, Jie. - : Elsevier BV, 2021
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7
Sustained neural rhythms reveal endogenous oscillations supporting speech perception. ...
Van Bree, Sander; Sohoglu, Ediz; Davis, Matt. - : Apollo - University of Cambridge Repository, 2021
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8
Language networks in aphasia and health: A 1000 participant activation likelihood estimation meta-analysis. ...
Stefaniak, James D; Alyahya, Reem SW; Lambon Ralph, Matthew. - : Apollo - University of Cambridge Repository, 2021
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9
A Bayesian optimization approach for rapidly mapping residual network function in stroke.
Lorenz, Romy; Johal, Michelle; Dick, Frederic. - : Oxford University Press (OUP), 2021. : Brain, 2021
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10
Deformation-based shape analysis of the hippocampus in the semantic variant of primary progressive aphasia and Alzheimer's disease.
Chapleau, Marianne; Bedetti, Christophe; Devenyi, Gabriel A. - : eScholarship, University of California, 2020
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A multi-level developmental approach to exploring individual differences in Down syndrome: genes, brain, behaviour, and environment. ...
Thomas, Michael SC; Ojinaga Alfageme, Olatz; D'Souza, Hana. - : Apollo - University of Cambridge Repository, 2020
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Rapid computations of spectrotemporal prediction error support perception of degraded speech. ...
Sohoglu, Ediz; Davis, Matt. - : Apollo - University of Cambridge Repository, 2020
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The Neural Time Course of Semantic Ambiguity Resolution in Speech Comprehension. ...
MacGregor, Lucy; Rodd, Jennifer M; Gilbert, Becky. - : Apollo - University of Cambridge Repository, 2020
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14
A unified model of post-stroke language deficits including discourse production and their neural correlates. ...
Alyahya, Reem SW; Halai, Ajay; Conroy, Paul. - : Apollo - University of Cambridge Repository, 2020
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A unified model of post-stroke language deficits including discourse production and their neural correlates.
Conroy, Paul; Halai, Ajay; Alyahya, Reem SW. - : Oxford University Press (OUP), 2020. : Brain, 2020
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A multi-level developmental approach to exploring individual differences in Down syndrome: genes, brain, behaviour, and environment.
Thomas, Michael SC; Ojinaga Alfageme, Olatz; D'Souza, Hana. - : Research in developmental disabilities, 2020
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Neuroimaging the consciousness of self: Review, and conceptual-methodological framework
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18
Physiological, behavioral and subjective sadness reactivity in frontotemporal dementia subtypes.
In: Social cognitive and affective neuroscience, vol 14, iss 12 (2019)
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19
Physiological, behavioral and subjective sadness reactivity in frontotemporal dementia subtypes.
In: Social cognitive and affective neuroscience, vol 14, iss 12 (2019)
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20
Neural correlates of abnormal auditory feedback processing during speech production in Alzheimer's disease.
In: Scientific reports, vol 9, iss 1 (2019)
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