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1
Increased connectivity among sensory and motor regions during visual and audiovisual speech perception
In: Open Access Publications (2022)
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2
A Bayesian optimization approach for rapidly mapping residual network function in stroke. ...
Lorenz, Romy; Johal, Michelle; Dick, Frederic. - : Apollo - University of Cambridge Repository, 2021
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3
Parental Perceptions and Decisions Regarding Maintaining Bilingualism in Autism. ...
Howard, Katie; Gibson, Jenny; Katsos, Napoleon. - : Apollo - University of Cambridge Repository, 2021
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4
Mexican Emotional Speech Database (MESD) ...
Duville, Mathilde Marie. - : Mendeley, 2021
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5
Age-related differences in the neural bases of phonological and semantic processes in the context of task-irrelevant information.
Truong, Trong-Kha; Johnson, Micah A; Madden, David J. - : Springer Science and Business Media LLC, 2021
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6
Influence of encoding difficulty, word frequency, and phonological regularity on age differences in word naming.
Madden, David J; Allen, Philip A; Bucur, Barbara. - : Informa UK Limited, 2021
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7
Infant and Toddler Child-Care Quality and Stability in Relation to Proximal and Distal Academic and Social Outcomes.
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8
Age-related differences in the neural bases of phonological and semantic processes.
Burke, Deborah M; Diaz, Michele T; Madden, David J. - : MIT Press - Journals, 2021
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9
Age-related differences in resolving semantic and phonological competition during receptive language tasks.
Madden, David J; Johnson, Micah A; Zhuang, Jie. - : Elsevier BV, 2021
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10
Predictive Neural Computations Support Spoken Word Recognition: Evidence from MEG and Competitor Priming. ...
Wang, Yingcan Carol; Sohoglu, Ediz; Gilbert, Becky. - : Apollo - University of Cambridge Repository, 2021
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11
Sustained neural rhythms reveal endogenous oscillations supporting speech perception. ...
Van Bree, Sander; Sohoglu, Ediz; Davis, Matt. - : Apollo - University of Cambridge Repository, 2021
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12
Language networks in aphasia and health: A 1000 participant activation likelihood estimation meta-analysis. ...
Stefaniak, James D; Alyahya, Reem SW; Lambon Ralph, Matthew. - : Apollo - University of Cambridge Repository, 2021
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13
Next-gen sequencing identifies non-coding variation disrupting miRNA-binding sites in neurological disorders
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14
Validation of the Portuguese version of the Evidence-Based Practice Questionnaire
Pereira, Rui Pedro Gomes; Guerra, Ana Cristina Pinheiro; Peixoto, Maria José. - : Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo, 2021
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15
A Bayesian optimization approach for rapidly mapping residual network function in stroke.
Lorenz, Romy; Johal, Michelle; Dick, Frederic. - : Oxford University Press (OUP), 2021. : Brain, 2021
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16
Predictive Neural Computations Support Spoken Word Recognition: Evidence from MEG and Competitor Priming.
Wang, Yingcan Carol; Henson, Rik; Sohoglu, Ediz. - : Society for Neuroscience, 2021. : Mrc Cognition And Brain Sciences Unit, 2021. : Department of Psychiatry, 2021. : J Neurosci, 2021
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17
Parental Perceptions and Decisions Regarding Maintaining Bilingualism in Autism.
Howard, Katie; Gibson, Jenny; Katsos, Napoleon. - : Springer Science and Business Media LLC, 2021. : J Autism Dev Disord, 2021
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18
DYT-TUBB4A (DYT4 Dystonia): New Clinical and Genetic Observations.
In: Neurology, vol. 96, no. 14, pp. e1887-e1897 (2021)
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19
The Visual Word Form Area compensates for auditory working memory dysfunction in schizophrenia.
In: Scientific reports, vol 10, iss 1 (2020)
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20
Deformation-based shape analysis of the hippocampus in the semantic variant of primary progressive aphasia and Alzheimer's disease.
Abstract: BackgroundIncreasing evidence shows that the semantic variant of primary progressive aphasia (svPPA) is characterized by hippocampal atrophy. However, less is known about disease-related morphological hippocampal changes. The goal of the present study is to conduct a detailed characterization of the impact of svPPA on global hippocampus volume and morphology compared with control subjects and patients with Alzheimer's disease (AD).MethodsWe measured hippocampal volume and deformation-based shape differences in 22 patients with svPPA compared with 99 patients with AD and 92 controls. Multiple Automatically Generated Templates Brain Segmentation Algorithm (MAGeT-Brain) was used on MRI images obtained at the diagnostic visit.ResultsComparable left and right hippocampal atrophy were observed in svPPA and AD. Deformation-based shape analysis showed a common pattern of morphological deformation in svPPA and AD compared with controls. More specifically, both svPPA and AD showed inward deformations in the dorsal surface of the hippocampus, from head to tail on the left side, and more limited to the anterior portion of the body in the right hemisphere. These results also pointed out that both diseases are characterized by a lateral displacement of the central part (body) of the hippocampus.DiscussionOur study provides critical new evidence of hippocampal morphological changes in svPPA, similar to those found in AD. These findings highlight the importance of considering morphological hippocampal changes as part of the anatomical profile of patients with svPPA.
Keyword: 2.1 Biological and endogenous factors; Acquired Cognitive Impairment; Adult; Aged; Aging; Alzheimer Disease; Alzheimer's disease; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD); Alzheimer’s disease; Aphasia; Atrophy; Automated segmentation; Biomedical Imaging; Brain; Brain Disorders; Clinical Research; Deformation-based shape analysis; Dementia; Female; Hippocampus; Humans; MAGeT brain; Magnetic Resonance Imaging; Male; Middle Aged; Neurodegenerative; Neurological; Neurosciences; Primary Progressive; Semantic variant of primary progressive aphasia; Semantics
URL: https://escholarship.org/uc/item/9c4370k3
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