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Infant and Toddler Child-Care Quality and Stability in Relation to Proximal and Distal Academic and Social Outcomes.
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Screen time in 36-month-olds at increased likelihood for ASD and ADHD.
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Screen time in 36-month-olds at increased likelihood for ASD and ADHD.
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Correlates of co-occurring eating disorders and substance use disorders: a case for dialectical behavior therapy.
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In: Eating disorders, vol 28, iss 2 (2020)
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Play and prosociality are associated with fewer externalizing problems in children with developmental language disorder: The role of early language and communication environment. ...
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Increased cortical reactivity to repeated tones at 8 months in infants with later ASD. ...
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Sensitivity to amplitude envelope rise time in infancy and vocabulary development at 3 years: A significant relationship. ...
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Sensitivity to amplitude envelope rise time in infancy and vocabulary development at 3 years: A significant relationship.
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Increased cortical reactivity to repeated tones at 8 months in infants with later ASD.
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Anomalous morphology in left hemisphere motor and premotor cortex of children who stutter
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Core vocabulary in the narratives of bilingual children with and without language impairment.
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In: International journal of speech-language pathology, vol 20, iss 7 (2018)
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The Receptive-Expressive Gap in English Narratives of Spanish-English Bilingual Children With and Without Language Impairment.
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In: Journal of speech, language, and hearing research : JSLHR, vol 61, iss 6 (2018)
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Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia.
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In: JAMA neurology, vol 75, iss 3 (2018)
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Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia.
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In: JAMA neurology, vol 75, iss 3 (2018)
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Contribution of parenting to complex syntax development in preschool children with developmental delays or typical development.
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In: Journal of intellectual disability research : JIDR, vol 62, iss 7 (2018)
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Brain basis of cognitive resilience: Prefrontal cortex predicts better reading comprehension in relation to decoding.
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In: PloS one, vol 13, iss 6 (2018)
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Cortical responses before 6 months of life associate with later autism. ...
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The role of phase synchronisation between low frequency amplitude modulations in child phonology and morphology speech tasks. ...
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Cortical responses before 6 months of life associate with later autism.
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Lloyd-Fox, Sarah; Blasi, A; Pasco, G; Gliga, T; Jones, EJH; Murphy, DGM; Elwell, CE; Charman, T; Johnson, Mark; BASIS Team. - : Wiley, 2018. : Eur J Neurosci, 2018
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Abstract:
Autism spectrum disorder (ASD) is a common, highly heritable, developmental disorder and later-born siblings of diagnosed children are at higher risk of developing ASD than the general population. Although the emergence of behavioural symptoms of ASD in toddlerhood is well characterized, far less is known about development during the first months of life of infants at familial risk. In a prospective longitudinal study of infants at familial risk followed to 36 months, we measured functional near-infrared spectroscopy (fNIRS) brain responses to social videos of people (i.e. peek-a-boo) compared to non-social images (vehicles) and human vocalizations compared to non-vocal sounds. At 4-6 months, infants who went on to develop ASD at 3 years (N = 5) evidenced-reduced activation to visual social stimuli relative to low-risk infants (N = 16) across inferior frontal (IFG) and posterior temporal (pSTS-TPJ) regions of the cortex. Furthermore, these infants also showed reduced activation to vocal sounds and enhanced activation to non-vocal sounds within left lateralized temporal (aMTG-STG/pSTS-TPJ) regions compared with low-risk infants and high-risk infants who did not develop ASD (N = 15). The degree of activation to both the visual and auditory stimuli correlated with parent-reported ASD symptomology in toddlerhood. These preliminary findings are consistent with later atypical social brain responses seen in children and adults with ASD, and highlight the need for further work interrogating atypical processing in early infancy and how it may relate to later social interaction and communication difficulties characteristic of ASD.
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Keyword:
Auditory Perception; Autism Spectrum Disorder; BASIS Team; Female; Functional Neuroimaging; Genetic Predisposition to Disease; Humans; Infant; Longitudinal Studies; Male; Near-Infrared; Prefrontal Cortex; Siblings; Social Perception; Spectroscopy; Speech Perception; Temporal Lobe; Visual Perception
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URL: https://www.repository.cam.ac.uk/handle/1810/292593 https://doi.org/10.17863/CAM.39754
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The role of phase synchronisation between low frequency amplitude modulations in child phonology and morphology speech tasks.
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