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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 3 4 5...14 Hits 1 – 20 of 275 1 Family history of FXTAS is associated with age-related cognitive-linguistic decline among mothers with the FMR1 premutation. Klusek, Jessica; Fairchild, Amanda; Moser, Carly... In: Journal of neurodevelopmental disorders, vol 14, iss 1 (2022) BASE Show details 2 Providing a parent-administered outcome measure in a bilingual family of a father and a mother of two adolescents with ASD: brief report. Del Hoyo Soriano, Laura; Bullard, Lauren; Thurman, Angela John... In: Developmental neurorehabilitation, vol 25, iss 2 (2022) BASE Show details 3 Neurodevelopmental outcomes among extremely premature infants with linear growth restriction. Meyers, JM; Tan, S; Bell, EF. - : Springer Science and Business Media LLC, 2021 BASE Show details 4 Next-gen sequencing identifies non-coding variation disrupting miRNA-binding sites in neurological disorders Devanna, P; Chen, X S; Ho, J. - 2021 BASE Show details 5 Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium. Miyagawa, Toji; Brushaber, Danielle; Syrjanen, Jeremy... In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020) BASE Show details 6 Use of the CDR® plus NACC FTLD in mild FTLD: Data from the ARTFL/LEFFTDS consortium. Miyagawa, Toji; Brushaber, Danielle; Syrjanen, Jeremy... In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020) BASE Show details 7 Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium. Miyagawa, Toji; Brushaber, Danielle; Syrjanen, Jeremy... In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020) BASE Show details 8 Use of the CDR® plus NACC FTLD in mild FTLD: Data from the ARTFL/LEFFTDS consortium. Miyagawa, Toji; Brushaber, Danielle; Syrjanen, Jeremy... In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020) BASE Show details 9 Screen time in 36-month-olds at increased likelihood for ASD and ADHD. Hill, Monique Moore; Gangi, Devon; Miller, Meghan. - : eScholarship, University of California, 2020 BASE Show details 10 Screen time in 36-month-olds at increased likelihood for ASD and ADHD. Hill, Monique Moore; Gangi, Devon; Miller, Meghan. - : eScholarship, University of California, 2020 BASE Show details 11 Health comorbidities and cognitive abilities across the lifespan in Down syndrome. ... Startin, Carla M; D'Souza, Hana; Ball, George. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 12 Play and prosociality are associated with fewer externalizing problems in children with developmental language disorder: The role of early language and communication environment. ... Toseeb, Umar; Gibson, Jenny; Newbury, Dianne F. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 13 Novel word learning deficits in infants at family risk for dyslexia. ... Kalashnikova, Marina; Goswami, Usha; Burnham, Denis. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 14 Health comorbidities and cognitive abilities across the lifespan in Down syndrome. Startin, Carla M; D'Souza, Hana; Ball, George; Hamburg, Sarah; Hithersay, Rosalyn; Hughes, Kate MO; Massand, Esha; Karmiloff-Smith, Annette; Thomas, Michael SC; LonDownS Consortium; Strydom, Andre. - : Springer Science and Business Media LLC, 2020. : J Neurodev Disord, 2020 Abstract: BACKGROUND: Down syndrome (DS) is associated with variable intellectual disability and multiple health and psychiatric comorbidities. The impact of such comorbidities on cognitive outcomes is unknown. We aimed to describe patterns of physical health and psychiatric comorbidity prevalence, and receptive language ability, in DS across the lifespan, and determine relationships with cognitive outcomes. METHODS: Detailed medical histories were collected and cognitive abilities measured using standardised tests for 602 individuals with DS from England and Wales (age range 3 months to 73 years). Differences in prevalence rates between age groups and between males and females were determined using chi-squared or Fisher's exact tests. In adults, rates for psychiatric comorbidities were compared to expected population rates using standardised morbidity ratios (SMRs). Adapted ANCOVA functions were constructed to explore age and sex associations with receptive language ability across the lifespan, and regression analyses were performed to determine whether the presence of health comorbidities or physical phenotypes predicted cognitive abilities. RESULTS: Multiple comorbidities showed prevalence differences across the lifespan, though there were few sex differences. In adults, SMRs were increased in males and decreased in females with DS for schizophrenia, bipolar disorder, and anxiety. Further, SMRs were increased in both males and females with DS for dementia, autism, ADHD, and depression, with differences more pronounced in females for dementia and autism, and in males for depression. Across the lifespan, receptive language abilities increasingly deviated from age-typical levels, and males scored poorer than females. Only autism and epilepsy were associated with poorer cognitive ability in those aged 16-35 years, with no relationships for physical health comorbidities, including congenital heart defects. CONCLUSIONS: Our results indicate the prevalence of multiple comorbidities varies across the lifespan in DS, and in adults, rates for psychiatric comorbidities show different patterns for males and females relative to expected population rates. Further, most health comorbidities are not associated with poorer cognitive outcomes in DS, apart from autism and epilepsy. It is essential for clinicians to consider such differences to provide appropriate care and treatment for those with DS and to provide prognostic information relating to cognitive outcomes in those with comorbidities. Keyword: 80 and over; Adolescent; Adult; Aged; Child; Cognition; Comorbidity; Down Syndrome; Female; Humans; Infant; Language Development Disorders; LonDownS Consortium; Longevity; Male; Mental Disorders; Middle Aged; Preschool; Sex Characteristics; United Kingdom; Young Adult URL: https://doi.org/10.17863/CAM.58181 https://www.repository.cam.ac.uk/handle/1810/311092 BASE Hide details 15 Neurodevelopmental outcomes among extremely premature infants with linear growth restriction. Meyers, JM; Tan, S; Bell, EF... In: Journal of perinatology : official journal of the California Perinatal Association, vol 39, iss 2 (2019) BASE Show details 16 Remapping the cognitive and neural profiles of children who struggle at school. ... Astle, Duncan; Bathelt, Joe; CALM Team. - : Apollo - University of Cambridge Repository, 2019 BASE Show details 17 STXBP1-associated neurodevelopmental disorder: a comparative study of behavioural characteristics. ... O'Brien, Sinéad; Ng-Cordell, Elise; DDD Study. - : Apollo - University of Cambridge Repository, 2019 BASE Show details 18 Early Risk Factors and Emotional Difficulties in Children at Risk of Developmental Language Disorder: A Population Cohort Study. ... St Clair, Michelle C; Forrest, Claire L; Yew, Shaun Goh Kok. - : Apollo - University of Cambridge Repository, 2019 BASE Show details 19 Remapping the cognitive and neural profiles of children who struggle at school. Astle, Duncan; Bathelt, Joe; CALM Team. - : Wiley, 2019. : Dev Sci, 2019 BASE Show details 20 Early Risk Factors and Emotional Difficulties in Children at Risk of Developmental Language Disorder: A Population Cohort Study. St Clair, Michelle C; Yew, Shaun Goh Kok; Forrest, Claire L. - : American Speech Language Hearing Association, 2019. : J Speech Lang Hear Res, 2019 BASE Show details Page: 1 2 3 4 5...14

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