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Metformin treatment in young children with fragile X syndrome.
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In: Molecular genetics & genomic medicine, vol 7, iss 11 (2019)
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Predictors for functional and anatomic outcomes in macular edema secondary to non-infectious uveitis
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Matas, Jessica; Llorenç, Victor; Fonollosa, Alex; Esquinas, Cristina; Diaz Valle, David; Berasategui, Barbara; Mesquida, Marina; Artaraz, Joseba; Rios, José; Adan Civera, Alfredo; Universitat Autònoma de Barcelona. - 2019
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Abstract:
Aims We aimed to investigate predictive factors for visual and anatomic outcomes in patients with macular edema secondary to non-infectious uveitis. Material and methods We conducted a multicenter, prospective, observational, 12-month follow-up study. Participants included in the study were adults with non-infectious uveitic macular edema (UME), defined as central subfoveal thickness (CST) of >300 μm as measured by spectral domain optical coherence tomography (SD-OCT) and fluid in the macula. Demographic, clinical and tomographic data was recorded at baseline, 1, 3, 6 and 12 months. Foveal-centered SD-OCT exploration was set as the gold-standard determination of UME using a standard Macular Cube 512x128 A-scan, within a 6 x 6 mm area, and the Enhanced High Definition Single-Line Raster. To assess favorable prognosis, the main outcomes analyzed were the best-corrected visual acuity (BCVA) and the CST. Favorable prognosis was defined as sustained improvement of BCVA (2 lines of gain of the Snellen scale) and CST (decrease of 20% of the initial value or <300 μm) within a 12 month period. Results Fifty-six eyes were analyzed. The number of eyes with sustained improvement in the CST was 48 (86.2%), against 23 (41.1%) eyes with sustained improvement in BCVA. Favorable prognosis, as defined above, was observed in 18 (32.1%) eyes. UME prognosis was negatively correlated with baseline foveal thickening, alteration in the vitreo-macular interface and cystoid macular edema. In contrast, bilaterally, systemic disease and the presence of anterior chamber cells were predictive of favorable prognosis. Conclusion Available treatment modalities in UME may avoid chronic UME and improve anatomic outcome. However, the proportion of functional amelioration observed during 12 months of follow-up is lower. Thicker CST, alteration in the vitreo-macular interface and cystoid macular edema may denote less favorable prognosis. Conversely, bilaterally, systemic disease and anterior chamber cells may be associated with favorable prognosis in UME.
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Keyword:
80 and over; Adult; Aged; Female; Follow-Up Studies; Fovea Centralis; Humans; Macular Edema; Male; Middle Aged; Optical Coherence; Outcome Assessment (Health Care); Prognosis; Prospective Studies; Tomography; Uveitis; Visual Acuity; Young Adult
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URL: https://ddd.uab.cat/record/223487
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Predictive Factors of Swallowing Disorders and Bronchopneumonia in Acute Ischemic Stroke.
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In: Journal of stroke and cerebrovascular diseases, vol. 28, no. 8, pp. 2148-2154 (2019)
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A physician-initiated intervention to increase colorectal cancer screening in Chinese patients.
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In: Cancer, vol 124 Suppl 7, iss Suppl 7 (2018)
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A physician-initiated intervention to increase colorectal cancer screening in Chinese patients.
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Quantitative assessment of white matter injury in preterm neonates: Association with outcomes.
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In: Brain and Mind Institute Researchers' Publications (2017)
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Multivariate pattern classification of pediatric Tourette syndrome using functional connectivity MRI.
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In: Developmental science, vol 19, iss 4 (2016)
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Grey Matter Density Predicts the Improvement of Naming Abilities After tDCS Intervention in Agrammatic Variant of Primary Progressive Aphasia
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Early response-to-intervention measures and criteria as predictors of reading disability in the beginning of third grade.
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In: Journal of learning disabilities, vol 48, iss 2 (2015)
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| 10 |
Narrative characteristics of genocide testimonies predict posttraumatic stress disorder symptoms years later.
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In: Psychological trauma : theory, research, practice and policy, vol 7, iss 3 (2015)
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| 11 |
Predictors of longitudinal outcome and recovery of pragmatic language and its relation to externalizing behaviour after pediatric traumatic brain injury
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| 12 |
The association between birth condition and neuropsychological functioning and educational attainment at school age: a cohort study.
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In: Arch Dis Child , 96 (1) pp. 30-37. (2011) (2011)
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Adult psychosocial outcomes of children with specific language impairment, pragmatic language impairment and autism.
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In: Symplectic Elements at Oxford ; Europe PubMed Central ; PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) ; Web of Science (Lite) (http://apps.webofknowledge.com/summary.do) ; Scopus (http://www.scopus.com/home.url) ; CrossRef (2009)
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| 14 |
Speech prognosis and need of pharyngeal flap for non syndromic vs syndromic Pierre Robin Sequence
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In: Journal of Pediatric Surgery, vol. 43, no. 4, pp. 668-674 (2008)
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Application of artificial intelligence to the management of urological cancer.
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In: Symplectic Elements at Oxford ; Europe PubMed Central ; PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) ; Web of Science (Lite) (http://apps.webofknowledge.com/summary.do) ; Scopus (http://www.scopus.com/home.url) ; CrossRef (2007)
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| 16 |
Aphasia in hyperacute stroke: language follows brain penumbra dynamics.
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In: Annals of Neurology, vol. 54, no. 3, pp. 321-329 (2003)
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Phoneme awareness is a better predictor of early reading skill than onset-rime awareness.
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In: Symplectic Elements at Oxford ; Europe PubMed Central ; PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) ; Scopus (http://www.scopus.com/home.url) (2002)
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| 18 |
Occlusion due to carotid artery dissection: a more severe disease than previously suggested.
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In: Archives of Neurology, vol. 59, no. 4, pp. 557-561 (2002)
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