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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 3 4 5 6 7...10 Hits 41 – 60 of 188 41 The Relationship between Expressive Language Sampling and Clinical Measures in Fragile X Syndrome and Typical Development. Shaffer, Rebecca C; Schmitt, Lauren; John Thurman, Angela... In: Brain sciences, vol 10, iss 2 (2020) BASE Show details 42 Artificial intelligence approaches to predicting and detecting cognitive decline in older adults: A conceptual review. Graham, Sarah A; Lee, Ellen E; Jeste, Dilip V. - : eScholarship, University of California, 2020 BASE Show details 43 Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers. Lee, Suzee E; Sias, Ana C; Kosik, Eena L. - : eScholarship, University of California, 2019 BASE Show details 44 Physiological, behavioral and subjective sadness reactivity in frontotemporal dementia subtypes. Hua, Alice Y; Chen, Kuan-Hua; Brown, Casey L... In: Social cognitive and affective neuroscience, vol 14, iss 12 (2019) BASE Show details 45 Factors that predict diagnostic stability in neurodegenerative dementia. Perry, David C; Datta, Samir; Miller, Zachary A... In: Journal of neurology, vol 266, iss 8 (2019) BASE Show details 46 Relationship Turmoil and Emotional Empathy in Frontotemporal Dementia. Takeda, Akitoshi; Sturm, Virginia E; Rankin, Katherine P... In: Alzheimer disease and associated disorders, vol 33, iss 3 (2019) BASE Show details 47 Divergent patterns of loss of interpersonal warmth in frontotemporal dementia syndromes are predicted by altered intrinsic network connectivity. Toller, Gianina; Yang, Winson FZ; Brown, Jesse A. - : eScholarship, University of California, 2019 BASE Show details 48 Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers. Lee, Suzee E; Sias, Ana C; Kosik, Eena L. - : eScholarship, University of California, 2019 BASE Show details 49 Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia. Miller, Zachary A; Spina, Salvatore; Pakvasa, Mikhail... In: Brain communications, vol 1, iss 1 (2019) BASE Show details 50 Divergent patterns of loss of interpersonal warmth in frontotemporal dementia syndromes are predicted by altered intrinsic network connectivity. Toller, Gianina; Yang, Winson FZ; Brown, Jesse A; Ranasinghe, Kamalini G; Shdo, Suzanne M; Kramer, Joel H; Seeley, William W; Miller, Bruce L; Rankin, Katherine P. - : eScholarship, University of California, 2019 Abstract: Loss of warmth is well-documented in behavioral variant frontotemporal dementia (bvFTD) and semantic variant primary progressive aphasia (svPPA) at a group level, and has been linked to salience (SN) and semantic-appraisal (SAN) network atrophy. However, clinical observations of individual patients show much greater heterogeneity, thus measuring this clinical variability and identifying the underlying neurologic mechanisms is a critical step for understanding the symptom profile of any one patient. We used reliable change indexes with premorbid and current informant-based evaluations to characterize patterns of change on the warmth subscale of the Interpersonal Adjective Scale (IAS) questionnaire in 132 patients (21 bvFTD, 19 svPPA, 22 nonfluent variant primary progressive aphasia [nfvPPA], 37 Alzheimer's disease [AD]) and 33 healthy older adults. We investigated whether individual differences in warmth change were reflected in SN or SAN functional connectivity, or structural volume of individual brain regions in these two networks. Though one subset of patients showed significant drop in warmth to abnormally low levels (bvFTD: 38%; svPPA: 21%; nfvPPA: 5%; AD: 11%), a second subset significantly dropped but remained within the clinically normal range (bvFTD: 33%; svPPA: 21%; nfvPPA: 9%; AD: 5%), and a third subset did not drop and stayed in the clinically normal range (bvFTD: 29%; svPPA: 58%; nfvPPA: 86%; AD: 84%). Furthermore, interpersonal warmth score was strongly predicted by SN functional connectivity (p < .01), but not by SAN functional connectivity or by structural volume in these networks. Our results extend earlier group-level findings by showing wide individual variability in degree of disease-related reduction of interpersonal warmth and SN functional connectivity in bvFTD and svPPA, and highlight new approaches to revealing how brain connectivity predicts behavior on an individual patient level. Our findings suggest that measures of interpersonal warmth can provide important clinical information about changes in underlying brain networks, and help clinicians and clinical researchers better identify which bvFTD and svPPA patients are at greater risk for interpersonal disruption. Keyword: 2.1 Biological and endogenous factors; Acquired Cognitive Impairment; Aged; Aging; Alzheimer's Disease; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD); Behavioral variant frontotemporal dementia; Brain Disorders; Clinical Research; Dementia; Female; Frontotemporal Dementia; Frontotemporal Dementia (FTD); Humans; Interpersonal warmth; Male; Middle Aged; Nerve Net; Neurodegenerative; Neurological; Neurosciences; Predictive Value of Tests; Resting-state fMRI; Salience network; Semantic variant primary progressive aphasia; Semantic-appraisal network; Social Skills URL: https://escholarship.org/uc/item/9qm527cr BASE Hide details 51 Physiological, behavioral and subjective sadness reactivity in frontotemporal dementia subtypes. Hua, Alice Y; Chen, Kuan-Hua; Brown, Casey L... In: Social cognitive and affective neuroscience, vol 14, iss 12 (2019) BASE Show details 52 Cortical encoding and decoding models of speech production Chartier, Josh. - : eScholarship, University of California, 2019 BASE Show details 53 Neural correlates of abnormal auditory feedback processing during speech production in Alzheimer's disease. Ranasinghe, Kamalini G; Kothare, Hardik; Kort, Naomi... In: Scientific reports, vol 9, iss 1 (2019) BASE Show details 54 Neural correlates of abnormal auditory feedback processing during speech production in Alzheimer's disease. Ranasinghe, Kamalini G; Kothare, Hardik; Kort, Naomi... In: Scientific reports, vol 9, iss 1 (2019) BASE Show details 55 Relationships Between Domain-Specific Cognition and Regional Brain Structure in a Typically Developing Cohort Curley, Lauren Butler. - : eScholarship, University of California, 2019 BASE Show details 56 Linguistic and Cultural Acceptability of a Spanish Translation of the Ohio State University Traumatic Brain Injury Identification Method Among Community-Dwelling Spanish-Dominant Older Adults. Hufstedler, Heather C; Dorsman, Karen A; Rivera, Ernesto J... In: Archives of rehabilitation research and clinical translation, vol 1, iss 3-4 (2019) BASE Show details 57 Muggle or magical?: Electrophysiological investigations of variation in the language-knowledge interface during reading Troyer, Melissa. - : eScholarship, University of California, 2019 BASE Show details 58 A Randomized Controlled Trial of Sertraline in Young Children With Autism Spectrum Disorder. Potter, Laura A; Scholze, Danielle A; Biag, Hazel Maridith B. - : eScholarship, University of California, 2019 BASE Show details 59 Pathogenic variants in USP7 cause a neurodevelopmental disorder with speech delays, altered behavior, and neurologic anomalies. Fountain, Michael D; Oleson, David S; Rech, Megan E... In: Genetics in medicine : official journal of the American College of Medical Genetics, vol 21, iss 8 (2019) BASE Show details 60 A Randomized Controlled Trial of Sertraline in Young Children With Autism Spectrum Disorder. Potter, Laura A; Scholze, Danielle A; Biag, Hazel Maridith B. - : eScholarship, University of California, 2019 BASE Show details Page: 1 2 3 4 5 6 7...10

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