| 41 |
The Relationship between Expressive Language Sampling and Clinical Measures in Fragile X Syndrome and Typical Development.
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In: Brain sciences, vol 10, iss 2 (2020)
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| 42 |
Artificial intelligence approaches to predicting and detecting cognitive decline in older adults: A conceptual review.
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| 43 |
Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers.
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| 44 |
Physiological, behavioral and subjective sadness reactivity in frontotemporal dementia subtypes.
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In: Social cognitive and affective neuroscience, vol 14, iss 12 (2019)
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| 45 |
Factors that predict diagnostic stability in neurodegenerative dementia.
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In: Journal of neurology, vol 266, iss 8 (2019)
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| 46 |
Relationship Turmoil and Emotional Empathy in Frontotemporal Dementia.
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In: Alzheimer disease and associated disorders, vol 33, iss 3 (2019)
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| 47 |
Divergent patterns of loss of interpersonal warmth in frontotemporal dementia syndromes are predicted by altered intrinsic network connectivity.
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| 48 |
Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers.
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| 49 |
Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia.
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Miller, Zachary A; Spina, Salvatore; Pakvasa, Mikhail; Rosenberg, Lynne; Watson, Christa; Mandelli, Maria Luisa; Paredes, Mercedes F; Joie, Renaud La; Rabinovici, Gil D; Rosen, Howard J; Grinberg, Lea T; Huang, Eric J; Miller, Bruce L; Seeley, William W; Gorno-Tempini, Maria Luisa
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In: Brain communications, vol 1, iss 1 (2019)
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Abstract:
An increased prevalence of dyslexia has been observed in individuals diagnosed with primary progressive aphasia, most notably the logopenic variant primary progressive aphasia. The underlying pathology most commonly associated with logopenic variant primary progressive aphasia is Alzheimer's disease. In this clinical case report series, we describe the neuropathological findings of three patients with logopenic variant primary progressive aphasia and developmental dyslexia, each demonstrating a pattern of cerebrocortical microdysgenesis, reminiscent of findings first reported in dyslexic individuals, alongside expected Alzheimer's disease pathology. Neurodevelopmental and most severe Alzheimer's disease pathological changes overlapped within perisylvian brain regions, areas associated with phonological deficits in both logopenic variant primary progressive aphasia and dyslexia. These three cases with pathological findings support the hypothesis that early-life neurodevelopmental changes might influence later-life susceptibility to neurodegenerative disease and could contribute to non-amnestic, early age-of-onset presentations of Alzheimer's disease. Larger studies investigating neurobiological vulnerability across the lifespan are needed.
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Keyword:
2.1 Biological and endogenous factors; Acquired Cognitive Impairment; Aging; Alzheimer's Disease; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD); Alzheimer’s disease; Aphasia; brain development; Brain Disorders; cortical developmental abnormalities; Dementia; dyslexia; Neurodegenerative; Neurological; Neurosciences; primary progressive aphasia
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URL: https://escholarship.org/uc/item/7v97r987
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| 50 |
Divergent patterns of loss of interpersonal warmth in frontotemporal dementia syndromes are predicted by altered intrinsic network connectivity.
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| 51 |
Physiological, behavioral and subjective sadness reactivity in frontotemporal dementia subtypes.
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In: Social cognitive and affective neuroscience, vol 14, iss 12 (2019)
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| 53 |
Neural correlates of abnormal auditory feedback processing during speech production in Alzheimer's disease.
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In: Scientific reports, vol 9, iss 1 (2019)
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| 54 |
Neural correlates of abnormal auditory feedback processing during speech production in Alzheimer's disease.
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In: Scientific reports, vol 9, iss 1 (2019)
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| 55 |
Relationships Between Domain-Specific Cognition and Regional Brain Structure in a Typically Developing Cohort
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| 56 |
Linguistic and Cultural Acceptability of a Spanish Translation of the Ohio State University Traumatic Brain Injury Identification Method Among Community-Dwelling Spanish-Dominant Older Adults.
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In: Archives of rehabilitation research and clinical translation, vol 1, iss 3-4 (2019)
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| 57 |
Muggle or magical?: Electrophysiological investigations of variation in the language-knowledge interface during reading
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| 58 |
A Randomized Controlled Trial of Sertraline in Young Children With Autism Spectrum Disorder.
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| 59 |
Pathogenic variants in USP7 cause a neurodevelopmental disorder with speech delays, altered behavior, and neurologic anomalies.
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In: Genetics in medicine : official journal of the American College of Medical Genetics, vol 21, iss 8 (2019)
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A Randomized Controlled Trial of Sertraline in Young Children With Autism Spectrum Disorder.
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