Page: 1... 3 4 5 6 7 8 9 10
121 |
Effects of Hormone Therapy on Cognition and Mood in Recently Postmenopausal Women: Findings from the Randomized, Controlled KEEPS-Cognitive and Affective Study.
|
|
|
|
In: PLoS medicine, vol 12, iss 6 (2015)
|
|
BASE
|
|
Show details
|
|
122 |
Neural basis of motivational approach and withdrawal behaviors in neurodegenerative disease.
|
|
|
|
In: Brain and behavior, vol 5, iss 9 (2015)
|
|
BASE
|
|
Show details
|
|
123 |
Atrophy patterns in early clinical stages across distinct phenotypes of Alzheimer's disease.
|
|
|
|
In: Human brain mapping, vol 36, iss 11 (2015)
|
|
BASE
|
|
Show details
|
|
124 |
Impaired Recognition and Regulation of Disgust Is Associated with Distinct but Partially Overlapping Patterns of Decreased Gray Matter Volume in the Ventroanterior Insula.
|
|
|
|
In: Biological psychiatry, vol 78, iss 7 (2015)
|
|
BASE
|
|
Show details
|
|
125 |
Criminal behavior in frontotemporal dementia and Alzheimer disease.
|
|
Liljegren, Madeleine; Naasan, Georges; Temlett, Julia; Perry, David C; Rankin, Katherine P; Merrilees, Jennifer; Grinberg, Lea T; Seeley, William W; Englund, Elisabet; Miller, Bruce L
|
|
In: JAMA neurology, vol 72, iss 3 (2015)
|
|
Abstract:
ImportanceNeurodegenerative diseases can cause dysfunction of neural structures involved in judgment, executive function, emotional processing, sexual behavior, violence, and self-awareness. Such dysfunctions can lead to antisocial and criminal behavior that appears for the first time in the adult or middle-aged individual or even later in life.ObjectiveTo investigate the frequency and type of criminal behavior among patients with a diagnosed dementing disorder.Design, setting, and participantsWe conducted a retrospective medical record review of 2397 patients who were seen at the University of California, San Francisco, Memory and Aging Center between 1999 and 2012, including 545 patients with Alzheimer disease (AD), 171 patients with behavioral variant of frontotemporal dementia (bvFTD), 89 patients with semantic variant of primary progressive aphasia, and 30 patients with Huntington disease. Patient notes containing specific keywords denoting criminal behavior were reviewed. Data were stratified by criminal behavior type and diagnostic groups.Main outcomes and measuresFrequencies of criminal behavior and χ² statistics were calculated.ResultsOf the 2397 patients studied, 204 (8.5%) had a history of criminal behavior that emerged during their illness. Of the major diagnostic groups, 42 of 545 patients (7.7%) with AD, 64 of 171 patients (37.4%) with bvFTD, 24 of 89 patients (27.0%) with semantic variant of primary progressive aphasia, and 6 of 30 patients (20%) with Huntington disease exhibited criminal behavior. A total of 14% of patients with bvFTD were statistically significantly more likely to present with criminal behavior compared with 2% of patients with AD (P < .001) and 6.4% were statistically significantly more likely to exhibit violence compared with 2% of patients with AD (P = .003). Common manifestations of criminal behavior in the bvFTD group included theft, traffic violations, sexual advances, trespassing, and public urination in contrast with those in the AD group, who commonly committed traffic violations, often related to cognitive impairment.Conclusions and relevanceCriminal behavior is more common in patients with bvFTD and semantic variant of primary progressive aphasia than in those with AD and is more likely to be an early manifestation of the disorder. Judicial evaluations of criminality in the demented individual might require different criteria than the classic "insanity defense" used in the American legal system; these individuals should be treated differently by the law. The appearance of new-onset criminal behavior in an adult should elicit a search for frontal and anterior temporal brain disease and for dementing disorders.
|
|
Keyword:
Acquired Cognitive Impairment; Affective Symptoms; Aged; Aging; Alzheimer Disease; Alzheimer's Disease; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD); Aphasia; Behavioral and Social Science; Brain Disorders; Clinical Research; Criminals; Dementia; Female; Frontotemporal Dementia; Humans; Male; Medical Records; Middle Aged; Neurodegenerative; Neurological; Neurosciences; Retrospective Studies; Theft; Violence; Violence Research
|
|
URL: https://escholarship.org/uc/item/0sw7t5fw
|
|
BASE
|
|
Hide details
|
|
126 |
The effects of study task on prestimulus subsequent memory effects in the hippocampus.
|
|
|
|
In: Hippocampus, vol 25, iss 11 (2015)
|
|
BASE
|
|
Show details
|
|
127 |
Predictors of longitudinal outcome and recovery of pragmatic language and its relation to externalizing behaviour after pediatric traumatic brain injury
|
|
|
|
BASE
|
|
Show details
|
|
128 |
Fusion analysis of functional MRI data for classification of individuals based on patterns of activation.
|
|
|
|
In: Brain and Mind Institute Researchers' Publications (2015)
|
|
BASE
|
|
Show details
|
|
129 |
Diffusion imaging of cerebral white matter in persons who stutter: evidence for network-level anomalies
|
|
|
|
BASE
|
|
Show details
|
|
130 |
Auditory cortex activation to natural speech and simulated cochlear implant speech measured with functional near-infrared spectroscopy.
|
|
|
|
BASE
|
|
Show details
|
|
131 |
Neural substrates of socioemotional self-awareness in neurodegenerative disease.
|
|
|
|
In: Brain and behavior, vol 4, iss 2 (2014)
|
|
BASE
|
|
Show details
|
|
132 |
Investigations of the syntax-brain relationship
|
|
|
|
In: Matchin, William. (2014). Investigations of the syntax-brain relationship. UC Irvine: Psychology. Retrieved from: http://www.escholarship.org/uc/item/9wk4z0dn (2014)
|
|
BASE
|
|
Show details
|
|
133 |
Parallel ICA of FDG-PET and PiB-PET in three conditions with underlying Alzheimer's pathology.
|
|
|
|
BASE
|
|
Show details
|
|
134 |
Parallel ICA of FDG-PET and PiB-PET in three conditions with underlying Alzheimer's pathology.
|
|
|
|
BASE
|
|
Show details
|
|
135 |
Human Speech Processing and Its Clinical Applications
|
|
|
|
In: Cheung, Connie. (2014). Human Speech Processing and Its Clinical Applications. UC San Francisco: Bioengineering. Retrieved from: http://www.escholarship.org/uc/item/7qr6d56t (2014)
|
|
BASE
|
|
Show details
|
|
136 |
Dissociated neural correlates of quantity processing of quantifiers, numbers, and numerosities.
|
|
|
|
In: Human brain mapping, vol 35, iss 2 (2014)
|
|
BASE
|
|
Show details
|
|
137 |
Functional neuroanatomical evidence for the double-deficit hypothesis of developmental dyslexia.
|
|
|
|
BASE
|
|
Show details
|
|
139 |
Cognitive control and its impact on recovery from aphasic stroke
|
|
|
|
In: BRAIN , 137 pp. 242-254. (2014) (2014)
|
|
BASE
|
|
Show details
|
|
140 |
The impact of multisensory integration deficits on speech perception in children with autism spectrum disorders.
|
|
|
|
In: Brain and Mind Institute Researchers' Publications (2014)
|
|
BASE
|
|
Show details
|
|
Page: 1... 3 4 5 6 7 8 9 10
|
|