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Cortical microstructure in primary progressive aphasia: a multicenter study.
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In: Alzheimer's research & therapy, vol 14, iss 1 (2022)
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Deformation-based shape analysis of the hippocampus in the semantic variant of primary progressive aphasia and Alzheimer's disease.
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Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia.
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In: JAMA neurology, vol 75, iss 3 (2018)
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Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease.
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Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease.
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Effects of HIV and childhood trauma on brain morphometry and neurocognitive function.
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In: Journal of neurovirology, vol 22, iss 2 (2016)
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Multivariate pattern classification of pediatric Tourette syndrome using functional connectivity MRI.
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In: Developmental science, vol 19, iss 4 (2016)
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Atrophy patterns in early clinical stages across distinct phenotypes of Alzheimer's disease.
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In: Human brain mapping, vol 36, iss 11 (2015)
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Parallel ICA of FDG-PET and PiB-PET in three conditions with underlying Alzheimer's pathology.
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Parallel ICA of FDG-PET and PiB-PET in three conditions with underlying Alzheimer's pathology.
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Neuroimaging correlates of handwriting quality as children learn to read and write.
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Neuroimaging correlates of handwriting quality as children learn to read and write.
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Gimenez, Paul; Bugescu, Nicolle; Black, Jessica M; Hancock, Roeland; Pugh, Kenneth; Nagamine, Masanori; Kutner, Emily; Mazaika, Paul; Hendren, Robert; McCandliss, Bruce D; Hoeft, Fumiko. - : eScholarship, University of California, 2014
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Abstract:
Reading and writing are related but separable processes that are crucial skills to possess in modern society. The neurobiological basis of reading acquisition and development, which critically depends on phonological processing, and to a lesser degree, beginning writing as it relates to letter perception, are increasingly being understood. Yet direct relationships between writing and reading development, in particular, with phonological processing is not well understood. The main goal of the current preliminary study was to examine individual differences in neurofunctional and neuroanatomical patterns associated with handwriting in beginning writers/readers. In 46 5-6 year-old beginning readers/writers, ratings of handwriting quality, were rank-ordered from best to worst and correlated with brain activation patterns during a phonological task using functional MRI, and with regional gray matter volume from structural T1 MRI. Results showed that better handwriting was associated negatively with activation and positively with gray matter volume in an overlapping region of the pars triangularis of right inferior frontal gyrus. This region, in particular in the left hemisphere in adults and more bilaterally in young children, is known to be important for decoding, phonological processing, and subvocal rehearsal. We interpret the dissociation in the directionality of the association in functional activation and morphometric properties in the right inferior frontal gyrus in terms of neural efficiency, and suggest future studies that interrogate the relationship between the neural mechanisms underlying reading and writing development.
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Keyword:
Basic Behavioral and Social Science; Behavioral and Social Science; Biomedical Imaging; Cognitive Sciences; Experimental Psychology; functional MRI; inferior frontal gyrus pars triangularis; Mental health; Neurological; Neurosciences; Pediatric; phonological processing; Psychology; reading; voxel-based morphometry; writing
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URL: https://escholarship.org/uc/item/6xp784z7
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White matter microstructure correlates of narrative production in typically developing children and children with high functioning autism.
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In: Neuropsychologia, vol 51, iss 10 (2013)
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White matter microstructure correlates of narrative production in typically developing children and children with high functioning autism.
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In: Neuropsychologia, vol 51, iss 10 (2013)
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Neural oscillatory correlates of speech auditory-motor integration in the cortex of healthy individuals and patients with schizophrenia
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In: Herman, Alexander Beaumont. (2013). Neural oscillatory correlates of speech auditory-motor integration in the cortex of healthy individuals and patients with schizophrenia. UC San Francisco: Bioengineering. Retrieved from: http://www.escholarship.org/uc/item/4sg0t34g (2013)
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Language proficiency modulates the recruitment of non-classical language areas in bilinguals.
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In: PloS one, vol 6, iss 3 (2011)
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