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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 3 4 Hits 1 – 20 of 75 1 Cortical microstructure in primary progressive aphasia: a multicenter study. Illán-Gala, Ignacio; Montal, Victor; Borrego-Écija, Sergi... In: Alzheimer's research & therapy, vol 14, iss 1 (2022) BASE Show details 2 Neural substrates of verbal repetition deficits in primary progressive aphasia. Dickerson, Bradford C.; Ezzo, Rania; Cordella, Claire. - 2021 BASE Show details 3 Investigating changes in connected speech in nonfluent/agrammatic primary progressive aphasia following script training ... Berstis, Karinne Viktoria. - : The University of Texas at Austin, 2021 BASE Show details 4 Μετωποκροταφική Άνοια και Γλώσσα – Μια Μελέτη Περίπτωσης ... Κουτσουρίδου, Λαρίσα Μενέλαου. - : Aristotle University of Thessaloniki, 2021 BASE Show details 5 Metabolomic changes associated with frontotemporal lobar degeneration syndromes Murley, Alexander G.; Jones, P. Simon; Coyle Gilchrist, Ian. - : Springer Berlin Heidelberg, 2021. : Journal of Neurology, 2021 BASE Show details 6 Connected speech markers of amyloid burden in primary progressive aphasia Slegers, Antoine; Chafouleas, Geneviève; Montembeault, Maxime. - : Elsevier, 2021 BASE Show details 7 Automated profiling of spontaneous speech in primary progressive aphasia and behavioral-variant frontotemporal dementia: An approach based on usage-frequency Zimmerer, Vitor,; Hardy, Chris,; Eastman, James; Dutta, Sonali; Varnet, Léo; Bond, Rebecca,; Russell, Lucy; Rohrer, Jonathan D; Warren, Jason D.; Varleya, Rosemary In: ISSN: 0010-9452 ; Cortex ; https://hal.archives-ouvertes.fr/hal-02993000 ; Cortex, Elsevier, 2020, 133, pp.103-119. ⟨10.1016/j.cortex.2020.08.027⟩ (2020) Abstract: International audience ; Language production provides important markers of neurological health. One feature of impairments of language and cognition, such as those that occur in stroke aphasia or Alzheimer's disease, is an overuse of high frequency, “familiar” expressions. We used computerized analysis to profile narrative speech samples from speakers with variants of frontotemporal dementia (FTD), including subtypes of primary progressive aphasia (PPA). Analysis was performed on language samples from 29 speakers with semantic variant PPA (svPPA), 25 speakers with logopenic variant PPA (lvPPA), 34 speakers with non-fluent variant PPA (nfvPPA), 14 speakers with behavioral variant FTD (bvFTD) and 20 older normal controls (NCs). We used frequency and collocation strength measures to determine use of familiar words and word combinations. We also computed word counts, content word ratio and a combination ratio, a measure of the degree to which the individual produces connected language. All dementia subtypes differed significantly from NCs. The most discriminating variables were word count, combination ratio, and content word ratio, each of which distinguished at least one dementia group from NCs. All participants with PPA, but not participants with bvFTD, produced significantly more frequent forms at the level of content words, word combinations, or both. Each dementia group differed from the others on at least one variable, and language production variables correlated with established behavioral measures of disease progression. A machine learning classifier, using narrative speech variables, achieved 90% accuracy when classifying samples as NC or dementia, and 59.4% accuracy when matching samples to their diagnostic group. Automated quantification of spontaneous speech in both language-led and non-language led dementias, is feasible. It allows extraction of syndromic profiles that complement those derived from standardized tests, warranting further evaluation as candidate biomarkers. Inclusion of frequency-based language variables benefits profiling and classification. Keyword: [SCCO.LING]Cognitive science/Linguistics; [SCCO]Cognitive science; [SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health; Dementia; Frontotemporal dementia; Language profiles; Primary progressive aphasia; Usage-frequency URL: https://doi.org/10.1016/j.cortex.2020.08.027 https://hal.archives-ouvertes.fr/hal-02993000 BASE Hide details 8 New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures. Boxer, Adam L; Gold, Michael; Feldman, Howard... In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020) BASE Show details 9 Use of the CDR® plus NACC FTLD in mild FTLD: Data from the ARTFL/LEFFTDS consortium. Miyagawa, Toji; Brushaber, Danielle; Syrjanen, Jeremy... In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020) BASE Show details 10 New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures. Boxer, Adam L; Gold, Michael; Feldman, Howard... In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020) BASE Show details 11 Use of the CDR® plus NACC FTLD in mild FTLD: Data from the ARTFL/LEFFTDS consortium. Miyagawa, Toji; Brushaber, Danielle; Syrjanen, Jeremy... In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020) BASE Show details 12 Metabolomic changes associated with frontotemporal lobar degeneration syndromes ... Murley, Alexander G.; Jones, P. Simon; Coyle Gilchrist, Ian. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 13 Metabolomic changes associated with frontotemporal lobar degeneration syndromes ... Murley, Alexander G.; Jones, P. Simon; Coyle Gilchrist, Ian. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 14 Metabolomic changes associated with frontotemporal lobar degeneration syndromes Murley, Alexander G.; Jones, P. Simon; Coyle Gilchrist, Ian. - : Springer Berlin Heidelberg, 2020. : Journal of Neurology, 2020 BASE Show details 15 The effects of a combined neurolinguistic intervention for primary progressive aphasia ; Eficácia de uma abordagem integrada de intervenção neurolinguística na afasia progressiva primária Cadório, Inês Ribeiro. - 2020 BASE Show details 16 Investigating changes in connected speech in nonfluent/agrammatic primary progressive aphasia following script training Berstis, Karinne Viktoria. - 2020 BASE Show details 17 Testing the therapeutic effects of transcranial direct current stimulation (tDCS) in semantic dementia: a double blind, sham controlled, randomized clinical trial Sanches, Clara; Levy, Richard; Benisty, Sarah... In: ISSN: 1745-6215 ; Trials ; https://hal.sorbonne-universite.fr/hal-02407657 ; Trials, BioMed Central, 2019, 20 (1), pp.632. ⟨10.1186/s13063-019-3613-z⟩ (2019) BASE Show details 18 Naming and Knowing Revisited: Eyetracking Correlates of Anomia in Progressive Aphasia ... Unkn Unknown. - : My University, 2019 BASE Show details 19 The utility of combined video implemented script training and discourse training in primary progressive aphasia : a single case study ... Safinia, Layla. - : The University of Texas at Austin, 2019 BASE Show details 20 Primary Progressive Aphasias in Bilinguals and Multilinguals Obler, Loraine K.; Korytkowska, Marta; Lerman, Aviva... In: Communication Disorders Faculty Publications (2019) BASE Show details Page: 1 2 3 4

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