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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 Hits 1 – 20 of 37 1 Down syndrome and parental depression: a double hit on early expressive language development D'Souza, Hana; Lathan, A.; Karmiloff Smith, Annette. - : Elsevier, 2020 BASE Show details 2 Attentional abilities constrain language development: a cross-syndrome infant/toddler study D'souza, Dean; D'Souza, Hana; Jones, Emily J.H.. - : Wiley, 2020 BASE Show details 3 A multi-level developmental approach to exploring individual differences in Down syndrome: genes, brain, behaviour, and environment Thomas, Michael; Ojinaga Alfageme, Olatz; D'Souza, H.; Patkee, P.; Rutherford, M.; Mok, K.; Hardy, J.; LonDownS Consortium, -; Karmiloff-Smith, Annette. - : Elsevier, 2020 Abstract: In this article, we focus on the causes of individual differences in Down syndrome (DS), exemplifying the multi-level, multi-method, lifespan developmental approach advocated by Karmiloff-Smith (1998, 2009, 2012, 2016). We evaluate the possibility of linking variations in infant and child development with variations in the (elevated) risk for Alzheimer’s disease (AD) in adults with DS. We review the theoretical basis for this argument, considering genetics, epigenetics, brain, behaviour and environment. In studies 1 and 2, we focus on variation in language development. We utilise data from the MacArthur-Bates Communicative Development Inventories (CDI; Fenson et al., 2007), and Mullen Scales of Early Learning (MSEL) receptive and productive language subscales (Mullen, 1995) from 84 infants and children with DS (mean age 2;3, range 0;7 to 5;3). As expected, there was developmental delay in both receptive and expressive vocabulary and wide individual differences. Study 1 examined the influence of an environmental measure (socio-economic status as measured by parental occupation) on the observed variability. SES did not predict a reliable amount of the variation. Study 2 examined the predictive power of a specific genetic measure (apolipoprotein APOE genotype) which modulates risk for AD in adulthood. There was no reliable effect of APOE genotype, though weak evidence that development was faster for the genotype conferring greater AD risk (ε4 carriers), consistent with recent observations in infant attention (D’Souza, Mason, et al., 2020). Study 3 considered the concerted effect of the DS genotype on early brain development. We describe new magnetic resonance imaging methods for measuring prenatal and neonatal brain structure in DS (e.g., volumes of supratentorial brain, cortex, cerebellar volume; Patkee et al., 2019). We establish the methodological viability of linking differences in early brain structure to measures of infant cognitive development, measured by the MSEL, as a potential early marker of clinical relevance. Five case studies are presented as proof of concept, but these are as yet too few to discern a pattern. Keyword: Psychological Sciences URL: https://doi.org/10.1016/j.ridd.2020.103638 https://eprints.bbk.ac.uk/id/eprint/31825/11/31825a.pdf https://eprints.bbk.ac.uk/id/eprint/31825/ https://eprints.bbk.ac.uk/id/eprint/31825/4/31825.pdf BASE Hide details 4 Fractionating nonword repetition: the contributions of short-term memory and oromotor praxis are different Carey, Daniel; Karmiloff-Smith, Annette; Krishnan, Saloni. - : Public Library of Science, 2017 BASE Show details 5 Intelligence as a developing function: a Neuroconstructivist approach Rinaldi, L.; Karmiloff-Smith, Annette. - : MDPI, 2017 BASE Show details 6 Syndromic Autism: progressing beyond current levels of description Glennon, Jennifer M.; Karmiloff-Smith, Annette; Thomas, Michael S.C.. - : Springer, 2017 BASE Show details 7 Distinct profiles of information-use characterize identity judgments in children and low-expertise adults Ewing, Louise; Karmiloff-Smith, Annette; Farran, E.K.. - : American Psychological Association, 2017 BASE Show details 8 Precursors to language development in typically and atypically developing infants and toddlers: the importance of embracing complexity D'Souza, Hana; D'Souza, Dean; Karmiloff-Smith, Annette. - : Cambridge Journals, 2017 BASE Show details 9 Audio-visual speech perception in infants and toddlers with Down syndrome, fragile X syndrome, and Williams syndrome Karmiloff-Smith, Annette; D'Souza, Hana; Johnson, Mark H.. - : Elsevier, 2016 BASE Show details 10 Bilingual children show an advantage in controlling verbal interference during spoken language comprehension Bright, P.; Filippi, R.; Marian, V.. - : Cambridge University Press, 2015 BASE Show details 11 Concurrent relations between face scanning and language: a cross-syndrome infant study D'Souza, Dean; D'Souza, H.; Johnson, Mark H.. - : Public Library of Science, 2015 BASE Show details 12 Williams syndrome: a surprising deficit in oromotor praxis in a population with proficient language production Krishnan, Saloni; Bergström, Lina; Alcock, K.J.. - : Elsevier, 2015 BASE Show details 13 Audio-visual speech perception: a developmental ERP investigation Karmiloff-Smith, Annette; Thomas, Michael S.C.; Knowland, Victoria C.P.. - : Wiley, 2014 BASE Show details 14 Narrowing perceptual sensitivity to the native language in infancy: exogenous influences on developmental timing Elsabbagh, Mayada; Hohenberger, A.; Campos, R.. - : MDPI, 2013 BASE Show details 15 Articulating novel words: children's oromotor skills predict non-word repetition abilities Krishnan, Saloni; Alcock, K.J.; Mercure, E.. - : American Speech-Language-Hearing Association, 2013 BASE Show details 16 Socioeconomic status and functional brain development - associations in early infancy Tomalski, Przemyslaw; Moore, D.G.; Ribeiro, H.. - : Wiley, 2013 BASE Show details 17 Sensitivity to consciousness: the morphological knowledge and model of redescription representational Karmiloff-Smith, Annette; Lorandi, A.. - : ediPUCRS, 2012 BASE Show details 18 Definitions versus categorization: assessing the development of lexico-semantic knowledge in Williams syndrome Purser, Harry; Thomas, Michael S.C.; Snoxall, Sarah. - : Wiley Blackwell, 2011 BASE Show details 19 Severity of hyperacusis predicts individual differences in speech perception in Williams Syndrome Cohen, H.; Karmiloff-Smith, Annette; Rosen, S.. - : Wiley, 2011 BASE Show details 20 A unique child: cognitive development: multi-lingualism Karmiloff, K.; Karmiloff-Smith, Annette. - : MA Education, 2011 BASE Show details Page: 1 2

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