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A transcallosal fibre system between homotopic inferior frontal regions supports complex linguistic processing
Kellmeyer, Philipp; Vry, Magnus‐Sebastian; Ball, Tonio. - : John Wiley and Sons Inc., 2019
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A transcallosal fibre system between homotopic inferior frontal regions supports complex linguistic processing
In: European journal of neuroscience. - 50, 10 (2019) , 3544-3556, ISSN: 1460-9568 (2019)
Abstract: Inferior frontal regions in the left and right hemisphere support different aspects of language processing. In the canonical model, left inferior frontal regions are mostly involved in processing based on phonological, syntactic and semantic features of language, whereas the right inferior frontal regions process paralinguistic aspects like affective prosody. Using diffusion tensor imaging (DTI)‐based probabilistic fibre tracking in 20 healthy volunteers, we identify a callosal fibre system connecting left and right inferior frontal regions that are involved in linguistic processing of varying complexity. Anatomically, we show that the interhemispheric fibres are highly aligned and distributed along a rostral to caudal gradient in the body and genu of the corpus callosum to connect homotopic inferior frontal regions. In the light of converging data, taking previous DTI‐based tracking studies and clinical case studies into account, our findings suggest that the right inferior frontal cortex not only processes paralinguistic aspects of language (such as affective prosody), as purported by the canonical model, but also supports the computation of linguistic aspects of varying complexity in the human brain. Our model may explain patterns of right‐hemispheric contribution to stroke recovery as well as disorders of prosodic processing. Beyond language‐related brain function, we discuss how inter‐species differences in interhemispheric connectivity and fibre density, including the system we described here may also explain differences in transcallosal information transfer and cognitive abilities across different mammalian species.
Keyword: Corpus callosum
URL: https://freidok.uni-freiburg.de/data/151329
https://doi.org/10.1111/ejn.14486
https://nbn-resolving.org/urn:nbn:de:bsz:25-freidok-1513293
https://www.freidok.uni-freiburg.de/dnb/download/151329
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3
Fronto-parietal dorsal and ventral pathways in the context of different linguistic manipulations
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 127 (2013) 2, 241-250
OLC Linguistik
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4
Damage to ventral and dorsal language pathways in acute aphasia
Kümmerer, Dorothee; Hartwigsen, Gesa; Kellmeyer, Philipp. - : Oxford University Press, 2013
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5
Damage to ventral and dorsal language pathways in acute aphasia
Kümmerer, Dorothee; Hartwigsen, Gesa; Kellmeyer, Philipp. - : Oxford University Press, 2013
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6
Damage to ventral and dorsal language pathways in acute aphasia
Kümmerer, Dorothee; Hartwigsen, Gesa; Kellmeyer, Philipp. - : Oxford University Press, 2013
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7
Ventral and dorsal pathways for language
Saur, Dorothee; Kreher, Björn W.; Schnell, Susanne. - : National Academy of Sciences, 2008
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