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Assessing children's understanding of complex syntax: a comparison of two methods
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Stage 2 Registered Report: There is no appreciable relationship between strength of hand preference and language ability in 6- to 7-year-old children
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Testing the unitary theory of language lateralization using functional transcranial Doppler sonography in adults
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Inconsistent lateralisation of language functions: a risk factor for language impairment?
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Growth in syntactic complexity between four years and adulthood: evidence from a narrative task
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Resounding failure to replicate links between developmental language disorder and cerebral lateralisation.
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The neuronal migration hypothesis of dyslexia: a critical evaluation 30 years on
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Phase 2 of CATALISE: a multinational and multidisciplinary Delphi consensus study of problems with language development: Terminology
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Assessing understanding of relative clauses : a comparison of multiple-choice comprehension versus repetition
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Phase 2 of CATALISE: a multinational and multidisciplinary Delphi consensus study of problems with language development: Terminology
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Phase 2 of CATALISE: a multinational and multidisciplinary Delphi consensus study of problems with language development: Terminology
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The effect of recall, reproduction, and restudy on word learning: a pre-registered study
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Phase 2 of CATALISE: a multinational and multidisciplinary Delphi consensus study of problems with language development: Terminology
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Phase 2 of CATALISE: a multinational and multidisciplinary Delphi consensus study of problems with language development: Terminology
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CATALISE: a multinational and multidisciplinary delphi consensus study. Identifying language impairments in children
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In: Symplectic Elements at Oxford ; Added by author ; ORA review team (2016)
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CATALISE: A multinational and multidisciplinary Delphi consensus study. Identifying language impairments in children
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In: PLoS ONE , 11 (7) , Article e0158753. (2016) (2016)
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CATALISE: A multinational and multidisciplinary Delphi consensus study. Identifying language impairments in children
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Early prediction of language and literacy problems: is 18 months too early?
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Increased prevalence of sex chromosome aneuploidies in specific language impairment and dyslexia
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Simpson, NH; Addis, L; Brandler, WM; Slonims, V; Clark, A; Watson, J; Scerri, TS; Hennessy, ER; Bolton, PF; Conti-Ramsden, G; Fairfax, BP; Knight, JC; Stein, J; Talcott, JB; O'Hare, A; Baird, G; Paracchini, S; Fisher, SE; Newbury, DF; Nudel, R; Monaco, AP; Simonoff, E; Pickles, A; Everitt, A; Seckl, J; Cowie, H; Cohen, W; Nasir, J; Bishop, DVM; Simkin, Z
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In: Symplectic Elements at Oxford ; Scopus (http://www.scopus.com/home.url) (2014)
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Abstract:
Aim: Sex chromosome aneuploidies increase the risk of spoken or written language disorders but individuals with specific language impairment (SLI) or dyslexia do not routinely undergo cytogenetic analysis. We assess the frequency of sex chromosome aneuploidies in individuals with language impairment or dyslexia. Method: Genome-wide single nucleotide polymorphism genotyping was performed in three sample sets: a clinical cohort of individuals with speech and language deficits (87 probands: 61 males, 26 females; age range 4 to 23 years), a replication cohort of individuals with SLI, from both clinical and epidemiological samples (209 probands: 139 males, 70 females; age range 4 to 17 years), and a set of individuals with dyslexia (314 probands: 224 males, 90 females; age range 7 to 18 years). Results: In the clinical language-impaired cohort, three abnormal karyotypic results were identified in probands (proband yield 3.4%). In the SLI replication cohort, six abnormalities were identified providing a consistent proband yield (2.9%). In the sample of individuals with dyslexia, two sex chromosome aneuploidies were found giving a lower proband yield of 0.6%. In total, two XYY, four XXY (Klinefelter syndrome), three XXX, one XO (Turner syndrome), and one unresolved karyotype were identified. Interpretation: The frequency of sex chromosome aneuploidies within each of the three cohorts was increased over the expected population frequency (approximately 0.25%) suggesting that genetic testing may prove worthwhile for individuals with language and literacy problems and normal non-verbal IQ. Early detection of these aneuploidies can provide information and direct the appropriate management for individuals. © 2013 The Authors. Developmental Medicine and Child Neurology published by John Wiley and Sons Ltd on behalf of Mac Keith Press.
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URL: https://doi.org/10.1111/dmcn.12294
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Training understanding of reversible sentences: A study comparing language-impaired children with age-matched and grammar-matched controls
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In: Symplectic Elements at Oxford ; Scopus (http://www.scopus.com/home.url) (2014)
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