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A Complementary Joint Training Approach Using Unpaired Speech and Text for Low-Resource Automatic Speech Recognition ...
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Functional maps of direct electrical stimulation-induced speech arrest and anomia: a multicentre retrospective study.
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In: Brain : a journal of neurology, vol 144, iss 8 (2021)
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The representation of variable tone sandhi patterns in Shanghai Wu
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In: Laboratory Phonology: Journal of the Association for Laboratory Phonology; Vol 12, No 1 (2021); 15 ; 1868-6354 (2021)
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Tracing Text Provenance via Context-Aware Lexical Substitution ...
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Fixel-based evidence of microstructural damage in crossing pathways improves language mapping in Post-stroke aphasia
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In: Neuroimage Clin (2021)
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Electrophysiological Signatures of Perceiving Alternated Tone in Mandarin Chinese: Mismatch Negativity to Underlying Tone Conflict
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In: Front Psychol (2021)
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The Evaluation Model of College Students' Mental Health in the Environment of Independent Entrepreneurship Using Neural Network Technology
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In: J Healthc Eng (2021)
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Functional maps of direct electrical stimulation-induced speech arrest and anomia: a multicentre retrospective study
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In: Brain (2021)
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Where is the speech production area? Evidence from direct cortical electrical stimulation mapping
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In: Brain (2021)
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The genetic determinants of language network dysconnectivity in drug-naïve early stage schizophrenia
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In: Brain and Mind Institute Researchers' Publications (2021)
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The genetic determinants of language network dysconnectivity in drug-naïve early stage schizophrenia
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In: Brain and Mind Institute Researchers' Publications (2021)
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The genetic determinants of language network dysconnectivity in drug-naïve early stage schizophrenia
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Du, Jingnan; Palaniyappan, Lena; Liu, Zhaowen; Cheng, Wei; Gong, Weikang; Zhu, Mengmeng; Wang, Jijun; Zhang, Jie; Feng, Jianfeng. - : Nature Publishing Group UK, 2021
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Abstract:
Schizophrenia is a neurocognitive illness of synaptic and brain network-level dysconnectivity that often reaches a persistent chronic stage in many patients. Subtle language deficits are a core feature even in the early stages of schizophrenia. However, the primacy of language network dysconnectivity and language-related genetic variants in the observed phenotype in early stages of illness remains unclear. This study used two independent schizophrenia dataset consisting of 138 and 53 drug-naïve first-episode schizophrenia (FES) patients, and 112 and 56 healthy controls, respectively. A brain-wide voxel-level functional connectivity analysis was conducted to investigate functional dysconnectivity and its relationship with illness duration. We also explored the association between critical language-related genetic (such as FOXP2) mutations and the altered functional connectivity in patients. We found elevated functional connectivity involving Broca’s area, thalamus and temporal cortex that were replicated in two FES datasets. In particular, Broca’s area - anterior cingulate cortex dysconnectivity was more pronounced for patients with shorter illness duration, while thalamic dysconnectivity was predominant in those with longer illness duration. Polygenic risk scores obtained from FOXP2-related genes were strongly associated with functional dysconnectivity identified in patients with shorter illness duration. Our results highlight the criticality of language network dysconnectivity, involving the Broca’s area in early stages of schizophrenia, and the role of language-related genes in this aberration, providing both imaging and genetic evidence for the association between schizophrenia and the determinants of language.
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URL: https://doi.org/10.1038/s41537-021-00141-8
http://wrap.warwick.ac.uk/149309/
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| 15 |
Linguistic diversity in a time of crisis: Language challenges of the COVID-19 pandemic. - Multilingua : Linguistic diversity in a time of crisis: Language challenges of the COVID-19 pandemic. -
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IDS Mannheim
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| 16 |
A Corpus-Based Investigation of Manner/State Complement Constructions in Mandarin Chinese ...
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Chinese postgraduate taught students' transitional experience in the UK: the role of social connections
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| 18 |
The /n/-/ŋ/ Asymmetry upon /ɻ/-Suffixation in Beijing and Elsewhere -- A Phonetically Based OT Analysis
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In: North East Linguistics Society (2020)
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| 19 |
Phonetic Duration Effects on Contour Tone Distribution
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In: North East Linguistics Society (2020)
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Poetry Translation From the Perspective of Creative Treason: Based on the Analysis of Xu Yuanzhong’s Translation of Spring View
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In: Cross-Cultural Communication; Vol 16, No 2 (2020): Cross-Cultural Communication; 64-68 ; 1923-6700 ; 1712-8358 (2020)
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