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1
The Autism Phenome Project: Toward Identifying Clinically Meaningful Subgroups of Autism
In: Front Neurosci (2022)
Abstract: One of the most universally accepted facts about autism is that it is heterogenous. Individuals diagnosed with autism spectrum disorder have a wide range of behavioral presentations and a variety of co-occurring medical and mental health conditions. The identification of more homogenous subgroups is likely to lead to a better understanding of etiologies as well as more targeted interventions and treatments. In 2006, we initiated the UC Davis MIND Institute Autism Phenome Project (APP) with the overarching goal of identifying clinically meaningful subtypes of autism. This ongoing longitudinal multidisciplinary study now includes over 400 children and involves comprehensive medical, behavioral, and neuroimaging assessments from early childhood through adolescence (2–19 years of age). We have employed several strategies to identify sub-populations within autistic individuals: subgrouping by neural, biological, behavioral or clinical characteristics as well as by developmental trajectories. In this Mini Review, we summarize findings to date from the APP cohort and describe progress made toward identifying meaningful subgroups of autism.
Keyword: Neuroscience
URL: https://doi.org/10.3389/fnins.2021.786220
http://www.ncbi.nlm.nih.gov/pubmed/35110990
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801875/
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2
Metformin treatment in young children with fragile X syndrome.
In: Molecular genetics & genomic medicine, vol 7, iss 11 (2019)
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3
A Randomized Controlled Trial of Sertraline in Young Children With Autism Spectrum Disorder.
Potter, Laura A; Scholze, Danielle A; Biag, Hazel Maridith B. - : eScholarship, University of California, 2019
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4
A Randomized Controlled Trial of Sertraline in Young Children With Autism Spectrum Disorder.
Potter, Laura A; Scholze, Danielle A; Biag, Hazel Maridith B. - : eScholarship, University of California, 2019
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5
Neural Processing and Production of Gesture in Children and Adolescents With Autism Spectrum Disorder.
Fourie, Emily; Palser, Eleanor R; Pokorny, Jennifer J. - : eScholarship, University of California, 2019
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6
A Randomized Controlled Trial of Sertraline in Young Children With Autism Spectrum Disorder
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7
Metformin treatment in young children with fragile X syndrome
Biag, Hazel Maridith B.; Potter, Laura A.; Wilkins, Victoria. - : John Wiley and Sons Inc., 2019
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8
The Multilingual CID-5: A New Tool to Study the Perception of Communicative Interactions in Different Languages
Manera, Valeria; Iani, Francesco; Bourgeois, Jeremy. - : eScholarship, University of California, 2015
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9
The Multilingual CID-5: A New Tool to Study the Perception of Communicative Interactions in Different Languages
Manera, Valeria; Ianì, Francesco; Bourgeois, Jérémy. - : Frontiers Media S.A., 2015
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10
The multilingual CID-5: A new tool to study the perception of communicative interactions in different languages
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11
Sertraline may improve language developmental trajectory in young children with fragile x syndrome: a retrospective chart review.
In: Autism research and treatment, vol 2012 (2012)
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12
Sertraline May Improve Language Developmental Trajectory in Young Children with Fragile X Syndrome: A Retrospective Chart Review
Indah Winarni, Tri; Chonchaiya, Weerasak; Adams, Evan. - : Hindawi Publishing Corporation, 2012
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13
Young adult female fragile X premutation carriers show age- and genetically-modulated cognitive impairments
In: Brain and cognition. - San Diego, Calif. [u.a.] : Elsevier Science 75 (2011) 3, 255-260
OLC Linguistik
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14
Holistic crowding of Mooney faces
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15
Can young infants add and subtract? : (incl. reply and author's reply)
In: Child development. - Malden, Ma. [u.a.] : Blackwell 71 (2000) 6, 1525-1539
BLLDB
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16
The drawbridge phenomenon : representational reasoning or perceptual preference?
In: Developmental psychology. - Richmond, Va. [u.a.] : American Psychological Association 35 (1999) 2, 427-435
BLLDB
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17
Effects of alcohol on speech : durations of isolated words, sentences and passages
In: Progress report no. 17 (1991) (Bloomington, IN, 1991), P. 285-302
MPI für Psycholinguistik
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18
Measuring the workload of comprehending spoken discourse : a first report
In: Progress report no. 16 (Bloomington, IN, 1990), P. 155-168
MPI für Psycholinguistik
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19
Effects of text structure on the comprehension of natural and synthetic speech
In: Progress report no. 16 (Bloomington, IN, 1990), P. 215-232
MPI für Psycholinguistik
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