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1
Review of Autism Profiles and Response to Sertraline in Fragile X Syndrome-Associated Autism vs. Non-syndromic Autism; Next Steps for Targeted Treatment.
Rajaratnam, Akash; Potter, Laura Axelrod; Biag, Hazel Maridith Barlahan. - : eScholarship, University of California, 2020
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2
Metformin treatment in young children with fragile X syndrome.
In: Molecular genetics & genomic medicine, vol 7, iss 11 (2019)
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3
A Randomized Controlled Trial of Sertraline in Young Children With Autism Spectrum Disorder.
Potter, Laura A; Scholze, Danielle A; Biag, Hazel Maridith B. - : eScholarship, University of California, 2019
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4
A Randomized Controlled Trial of Sertraline in Young Children With Autism Spectrum Disorder.
Potter, Laura A; Scholze, Danielle A; Biag, Hazel Maridith B. - : eScholarship, University of California, 2019
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5
A Randomized Controlled Trial of Sertraline in Young Children With Autism Spectrum Disorder
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6
Metformin treatment in young children with fragile X syndrome
Abstract: BACKGROUND: Metformin is a drug commonly used in individuals with type 2 diabetes, obesity, and impaired glucose tolerance. It has a strong safety profile in both children and adults. Studies utilizing the Drosophila model and knock out mouse model of fragile X syndrome (FXS) have found metformin to rescue memory, social novelty deficits, and neuroanatomical abnormalities. These studies provided preliminary evidence that metformin could be used as a targeted treatment for the cognitive and behavioral problems associated with FXS. Previously, a case series of children and adults with FXS treated with metformin demonstrated improvements in irritability, social responsiveness, language, and hyperactivity. METHODS: Here, we present nine children with FXS between 2 and 7 years of age who were treated clinically with metformin and monitored for behavioral and metabolic changes. RESULTS: Parent reports and developmental testing before and after metformin are presented. There were improvements in language development and behavior (such as lethargy and stereotypy) in most of the patients. CONCLUSION: These results support the need for a controlled trial of metformin in children with FXS under 7 years old whose brains are in a critical developmental window and thus may experience a greater degree of clinical benefit from metformin.
Keyword: Original Articles
URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6825840/
https://doi.org/10.1002/mgg3.956
http://www.ncbi.nlm.nih.gov/pubmed/31520524
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7
Drama to go! Hints and hands-on activities for the classroom
Sambanis, Michaela; Baran, Delil; Beltrop, Kimon. - : Department of German, University College Cork, 2013
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8
Abnormal N400 word repetition effects in fragile X-associated tremor/ataxia syndrome
Olichney, John M.; Chan, Shiaohui; Wong, Ling M.. - : Oxford University Press, 2010
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9
Abnormal N400 word repetition effects in fragile X-associated tremor/ataxia syndrome
Olichney, John M.; Chan, Shiaohui; Wong, Ling M.. - : Oxford University Press, 2010
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10
Abnormal N400 word repetition effects in fragile X-associated tremor/ataxia syndrome
Olichney, John M.; Chan, Shiaohui; Wong, Ling M.. - : Oxford University Press, 2010
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11
Unterrichtsreihe zum Thema: Wie wichtig ist Sportkleidung? : Beeinflussung jugendlicher Identitätsbildung durch Werbung für Sportmode
Schneider, Andrea [Verfasser]. - München : GRIN Verlag GmbH, 2007
DNB Subject Category Language
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12
Beyond Machiavelli : tools for coping with conflict
Fisher, Roger; Kopelman, Elizabeth; Schneider, Andrea Kupfer. - Cambridge, MA : Harvard University Press, 1994
MPI für Psycholinguistik
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13
CALL-Software auf dem Prüfstand : ein benutzerfreundliches Kriterienschema zur Analyse von CALL-Programmen
Schneider, Andrea. - Duisburg, 1989
UB Frankfurt Linguistik
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14
Call-Software auf dem Prüfstand : ein benutzerfreundliches Kriterienschema zur Analyse von Call-Programmen
Schneider, Andrea. - Duisburg : LAUD, 1989
IDS Mannheim
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