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The genetic architecture of language functional connectivity
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In: ISSN: 1053-8119 ; EISSN: 1095-9572 ; NeuroImage ; https://hal.sorbonne-universite.fr/hal-03566120 ; NeuroImage, Elsevier, 2022, 249, pp.118795. ⟨10.1016/j.neuroimage.2021.118795⟩ (2022)
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The "Fat Face" illusion: A robust adaptation for processing pairs of faces
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In: ISSN: 0042-6989 ; EISSN: 0042-6989 ; Vision Research ; https://hal.archives-ouvertes.fr/hal-03579276 ; Vision Research, Elsevier, 2022, 195, pp.108015. ⟨10.1016/j.visres.2022.108015⟩ (2022)
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From Biological Synapses to “Intelligent” Robots
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In: ISSN: 2079-9292 ; Electronics ; https://hal.archives-ouvertes.fr/hal-03590998 ; Electronics, MDPI, 2022, 11 (5), pp.707. ⟨10.3390/electronics11050707⟩ (2022)
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Biological constraints on configural odour mixture perception
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In: ISSN: 0022-0949 ; EISSN: 1477-9145 ; Journal of Experimental Biology ; https://hal-cnrs.archives-ouvertes.fr/hal-03610253 ; Journal of Experimental Biology, The Company of Biologists, 2022, 225 (6), pp.jeb242274. ⟨10.1242/jeb.242274⟩ ; https://journals.biologists.com/jeb/article-abstract/225/6/jeb242274/274695/Biological-constraints-on-configural-odour-mixture (2022)
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Trans-Translation Is an Appealing Target for the Development of New Antimicrobial Compounds
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In: EISSN: 2076-2607 ; Microorganisms ; https://hal.archives-ouvertes.fr/hal-03575603 ; Microorganisms, 2022, 10 (1), ⟨10.3390/microorganisms10010003⟩ (2022)
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Abstract:
International audience ; Because of the ever-increasing multidrug resistance in microorganisms, it is crucial that we find and develop new antibiotics, especially molecules with different targets and mechanisms of action than those of the antibiotics in use today. Translation is a fundamental process that uses a large portion of the cell's energy, and the ribosome is already the target of more than half of the antibiotics in clinical use. However, this process is highly regulated, and its quality control machinery is actively studied as a possible target for new inhibitors. In bacteria, ribosomal stalling is a frequent event that jeopardizes bacterial wellness, and the most severe form occurs when ribosomes stall at the 3 '-end of mRNA molecules devoid of a stop codon. Trans-translation is the principal and most sophisticated quality control mechanism for solving this problem, which would otherwise result in inefficient or even toxic protein synthesis. It is based on the complex made by tmRNA and SmpB, and because trans-translation is absent in eukaryotes, but necessary for bacterial fitness or survival, it is an exciting and realistic target for new antibiotics. Here, we describe the current and future prospects for developing what we hope will be a novel generation of trans-translation inhibitors.
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Keyword:
[SDV]Life Sciences [q-bio]; antibiotics; ribosome; SmpB; tmRNA; trans-translation
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URL: https://hal.archives-ouvertes.fr/hal-03575603 https://doi.org/10.3390/microorganisms10010003
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Meta-Analysis of the Functional Neuroimaging Literature with Probabilistic Logic Programming
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In: https://hal.archives-ouvertes.fr/hal-03590714 ; 2022 (2022)
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Relationships between Sense of Community, Authenticity, and Meaning in Life in Four Social Communities in France
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In: ISSN: 2071-1050 ; Sustainability ; https://hal-cnam.archives-ouvertes.fr/hal-03622623 ; Sustainability, MDPI, 2022, 14 (2), pp.1018. ⟨10.3390/su14021018⟩ (2022)
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Evaluation of two artificial infection methods of live ticks as tools for studying interactions between tick-borne viruses and their tick vectors
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In: ISSN: 2045-2322 ; EISSN: 2045-2322 ; Scientific Reports ; https://hal-anses.archives-ouvertes.fr/anses-03580231 ; Scientific Reports, Nature Publishing Group, 2022, 12 (1), pp.491. ⟨10.1038/s41598-021-04498-9⟩ (2022)
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Cognitive assessment scale for stroke patients (CASP): A multicentric validation study
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In: ISSN: 1877-0657 ; Annals of Physical and Rehabilitation Medicine ; https://hal.univ-grenoble-alpes.fr/hal-03647576 ; Annals of Physical and Rehabilitation Medicine, Elsevier Masson, 2022, 65 (3), pp.101594. ⟨10.1016/j.rehab.2021.101594⟩ (2022)
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Anxious voice and avoidant language in interaction with a woman wearing an Islamic headscarf: field-experimental evidence from the Paris metro
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In: https://hal.archives-ouvertes.fr/hal-03140246 ; 2022 (2022)
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Anxious voice and avoidant language in interaction with a woman wearing an Islamic headscarf: field-experimental evidence from the Paris metro
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In: https://hal.archives-ouvertes.fr/hal-03140246 ; 2022 (2022)
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A lexical approach for identifying behavioural action sequences
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In: ISSN: 1553-734X ; EISSN: 1553-7358 ; PLoS Computational Biology ; https://hal.sorbonne-universite.fr/hal-03521462 ; PLoS Computational Biology, Public Library of Science, 2022, 18 (1), pp.e1009672. ⟨10.1371/journal.pcbi.1009672⟩ (2022)
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Hippocampal and auditory contributions to speech segmentation
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In: ISSN: 0010-9452 ; Cortex ; https://hal.archives-ouvertes.fr/hal-03604957 ; Cortex, Elsevier, 2022, ⟨10.1016/j.cortex.2022.01.017⟩ (2022)
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Évaluation de la perception des sons de parole chez les populations pédiatriques : réflexion sur les épreuves existantes
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In: ISSN: 0298-6477 ; EISSN: 2117-7155 ; Glossa ; https://hal.archives-ouvertes.fr/hal-03646757 ; Glossa, UNADREO - Union NAtionale pour le Développement de la Recherche en Orthophonie, 2022, 132, pp.1-27 ; https://www.glossa.fr/index.php/glossa/article/view/1043 (2022)
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Ear Asymmetry and Contextual Influences on Speech Perception in Hearing-Impaired Patients
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In: ISSN: 1662-4548 ; EISSN: 1662-453X ; Frontiers in Neuroscience ; https://hal.archives-ouvertes.fr/hal-03648312 ; Frontiers in Neuroscience, Frontiers, 2022, 16, ⟨10.3389/fnins.2022.801699⟩ (2022)
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Automatic generation of the complete vocal tract shape from the sequence of phonemes to be articulated
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In: ISSN: 0167-6393 ; EISSN: 1872-7182 ; Speech Communication ; https://hal.univ-lorraine.fr/hal-03650212 ; Speech Communication, Elsevier : North-Holland, 2022, ⟨10.1016/j.specom.2022.04.004⟩ (2022)
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Inter-Individual Variability in Dorsal Stream Dynamics During Word Production
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In: https://hal.archives-ouvertes.fr/hal-03629184 ; 2022 (2022)
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Rapport et Bilan Scientifique - 2e Symposium sur la Politique Linguistique Familiale 2021
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In: https://hal-inalco.archives-ouvertes.fr/hal-03525635 ; [Rapport de recherche] INALCO, Sorbonne Paris-Cité (SPC). 2022 (2022)
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Using a pupal exuvia to designate the undamaged neotype of a species belonging to a complex of sibling species – the case of Aedes coluzzii (Diptera, Culicidae)
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In: ISSN: 1252-607X ; EISSN: 1776-1042 ; Parasite ; https://hal.archives-ouvertes.fr/hal-03623918 ; Parasite, EDP Sciences, 2022, 29, pp.1-8. ⟨10.1051/parasite/2022020⟩ (2022)
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Cross-Situational Learning Towards Robot Grounding
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In: https://hal.archives-ouvertes.fr/hal-03628290 ; 2022 (2022)
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