• Refine your search:
  • 
    Keyword:
    
    • Progressive supranuclear palsy (17)
    • progressive supranuclear palsy (14)
    • Dementia (11)
    • Humans (11)
    • Neurosciences (9)
    • frontotemporal dementia (9)
    • Corticobasal syndrome (8)
    • Acquired Cognitive Impairment (7)
    • Alzheimer's disease (7)
    • Brain Disorders (7)
    •   more
  • 
    Creator / Publisher:
    
    • Patterson, Karalyn (8)
    • Rowe, James B. (8)
    • Tsvetanov, Kamen A. (8)
    • Wiggins, Julie (7)
    • Bowns, Lucy (6)
    • Coyle Gilchrist, Ian (6)
    • Jones, P. Simon (6)
    • Miller, Bruce L (6)
    • Boxer, Adam L (5)
    • Garrard, Peter (4)
    •   more
  • 
    Year:
    
    • 2021 (6)
    • 2020 (10)
    • 2019 (4)
    • 2018 (4)
    • 2016 (5)
    • 2015 (1)
    • 2013 (2)
    • 2012 (1)
    • 2011 (1)
    • 2010 (2)
    •   more
  • 
    Medium
  • 
    Type
  • 
    BLLDB-Access:
    • free (44)
    • subject to license (0)

Search in the Catalogues and Directories

All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Page: 1 2 3 Hits 1 – 20 of 44 1 Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool. ... Peterson, Katie A; Jones, P Simon; Patel, Nikil. - : Apollo - University of Cambridge Repository, 2021 BASE Show details 2 Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool ... Peterson, Katie A.; Jones, P. Simon; Patel, Nikil. - : Apollo - University of Cambridge Repository, 2021 BASE Show details 3 Language impairment in progressive supranuclear palsy and corticobasal syndrome Peterson, Katie A.; Patterson, Karalyn; Rowe, James B.. - : Springer Berlin Heidelberg, 2021. : Journal of Neurology, 2021 BASE Show details 4 Metabolomic changes associated with frontotemporal lobar degeneration syndromes Murley, Alexander G.; Jones, P. Simon; Coyle Gilchrist, Ian; Bowns, Lucy; Wiggins, Julie; Tsvetanov, Kamen A.; Rowe, James B.. - : Springer Berlin Heidelberg, 2021. : Journal of Neurology, 2021 Abstract: Funder: Holt Fellowship ; Funder: Cambridge Centre for Parkinson plus ; Funder: National Institute for Health Research; doi: http://dx.doi.org/10.13039/501100000272 ; Abstract: Objective: Widespread metabolic changes are seen in neurodegenerative disease and could be used as biomarkers for diagnosis and disease monitoring. They may also reveal disease mechanisms that could be a target for therapy. In this study we looked for blood-based biomarkers in syndromes associated with frontotemporal lobar degeneration. Methods: Plasma metabolomic profiles were measured from 134 patients with a syndrome associated with frontotemporal lobar degeneration (behavioural variant frontotemporal dementia n = 30, non fluent variant primary progressive aphasia n = 26, progressive supranuclear palsy n = 45, corticobasal syndrome n = 33) and 32 healthy controls. Results: Forty-nine of 842 metabolites were significantly altered in frontotemporal lobar degeneration syndromes (after false-discovery rate correction for multiple comparisons). These were distributed across a wide range of metabolic pathways including amino acids, energy and carbohydrate, cofactor and vitamin, lipid and nucleotide pathways. The metabolomic profile supported classification between frontotemporal lobar degeneration syndromes and controls with high accuracy (88.1–96.6%) while classification accuracy was lower between the frontotemporal lobar degeneration syndromes (72.1–83.3%). One metabolic profile, comprising a range of different pathways, was consistently identified as a feature of each disease versus controls: the degree to which a patient expressed this metabolomic profile was associated with their subsequent survival (hazard ratio 0.74 [0.59–0.93], p = 0.0018). Conclusions: The metabolic changes in FTLD are promising diagnostic and prognostic biomarkers. Further work is required to replicate these findings, examine longitudinal change, and test their utility in differentiating between FTLD syndromes that are pathologically distinct but phenotypically similar. Keyword: Corticobasal syndrome; Frontotemporal dementia; Frontotemporal lobar degeneration; Metabolomics; Original Communication; Primary progressive aphasia; Progressive supranuclear palsy URL: https://doi.org/10.17863/CAM.66825 https://www.repository.cam.ac.uk/handle/1810/319704 BASE Hide details 5 Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool Peterson, Katie A.; Jones, P. Simon; Patel, Nikil. - : Frontiers Media S.A., 2021. : Frontiers in Aging Neuroscience, 2021 BASE Show details 6 Language Disorder in Progressive Supranuclear Palsy and Corticobasal Syndrome: Neural Correlates and Detection by the MLSE Screening Tool. Peterson, Katie A; Jones, P Simon; Patel, Nikil... In: essn: 1663-4365 ; nlmid: 101525824 (2021) BASE Show details 7 New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures. Boxer, Adam L; Gold, Michael; Feldman, Howard... In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020) BASE Show details 8 Depressive Symptom Profiles Predict Specific Neurodegenerative Disease Syndromes in Early Stages. Shdo, Suzanne M; Ranasinghe, Kamalini G; Sturm, Virginia E. - : eScholarship, University of California, 2020 BASE Show details 9 Depressive Symptom Profiles Predict Specific Neurodegenerative Disease Syndromes in Early Stages. Shdo, Suzanne M; Ranasinghe, Kamalini G; Sturm, Virginia E. - : eScholarship, University of California, 2020 BASE Show details 10 New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures. Boxer, Adam L; Gold, Michael; Feldman, Howard... In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020) BASE Show details 11 Metabolomic changes associated with frontotemporal lobar degeneration syndromes. ... Murley, Alexander; Jones, Simon; Coyle Gilchrist, Ian. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 12 Metabolomic changes associated with frontotemporal lobar degeneration syndromes ... Murley, Alexander G.; Jones, P. Simon; Coyle Gilchrist, Ian. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 13 Metabolomic changes associated with frontotemporal lobar degeneration syndromes ... Murley, Alexander G.; Jones, P. Simon; Coyle Gilchrist, Ian. - : Apollo - University of Cambridge Repository, 2020 BASE Show details 14 Metabolomic changes associated with frontotemporal lobar degeneration syndromes. Murley, Alexander; Jones, Simon; Coyle Gilchrist, Ian. - : Springer Science and Business Media LLC, 2020. : J Neurol, 2020 BASE Show details 15 Behavioural disinhibition in the syndromes associated with frontotemporal lobar degeneration Murley, Alexander. - : University of Cambridge, 2020 BASE Show details 16 Metabolomic changes associated with frontotemporal lobar degeneration syndromes Murley, Alexander G.; Jones, P. Simon; Coyle Gilchrist, Ian. - : Springer Berlin Heidelberg, 2020. : Journal of Neurology, 2020 BASE Show details 17 Factors that predict diagnostic stability in neurodegenerative dementia. Perry, David C; Datta, Samir; Miller, Zachary A... In: Journal of neurology, vol 266, iss 8 (2019) BASE Show details 18 Factors that predict diagnostic stability in neurodegenerative dementia. Perry, David C; Datta, Samir; Miller, Zachary A... In: Journal of neurology, vol 266, iss 8 (2019) BASE Show details 19 Language impairment in progressive supranuclear palsy and corticobasal syndrome ... Peterson, Katie A.; Patterson, Karalyn; Rowe, James B.. - : Apollo - University of Cambridge Repository, 2019 BASE Show details 20 The clinico-metabolic correlates of language impairment in corticobasal syndrome and progressive supranuclear palsy Dodich, Alessandra; Cerami, Chiara; Inguscio, Emanuela... In: ISSN: 2213-1582 ; NeuroImage: Clinical (2019) P. 102009 (2019) BASE Show details Page: 1 2 3

Mobile view All Catalogues UB Frankfurt Linguistik 0 IDS Mannheim 0 OLC Linguistik 0 UB Frankfurt Retrokatalog 0 DNB Subject Category Language 0 Institut für Empirische Sprachwissenschaft 0 Leibniz-Centre General Linguistics (ZAS) 0 Bibliographies BLLDB 0 BDSL 0 IDS Bibliografie zur deutschen Grammatik 0 IDS Bibliografie zur Gesprächsforschung 0 IDS Konnektoren im Deutschen 0 IDS Präpositionen im Deutschen 0 IDS OBELEX meta 0 MPI-SHH Linguistics Collection 0 MPI for Psycholinguistics 0 Linked Open Data catalogues Annohub 0 Online resources Link directory 0 Journal directory 0 Database directory 0 Dictionary directory 0 Open access documents BASE 44 Linguistik-Repository 0 IDS Publikationsserver 0 Online dissertations 0 Language Description Heritage 0