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Hits 1 – 13 of 13
1
How to make a tongue: Cellular and molecular regulation of muscle and connective tissue formation during mammalian tongue development
Cobourne, Martyn,
;
Iseki, Sachiko
;
Birjandi, Anahid
...
In: ISSN: 1084-9521 ; EISSN: 1096-3634 ; Seminars in Cell and Developmental Biology ; https://hal-univ-bourgogne.archives-ouvertes.fr/hal-01820871 ; Seminars in Cell and Developmental Biology, Elsevier, In press, ⟨10.1016/j.semcdb.2018.04.016⟩ ; https://www.sciencedirect.com/science/article/pii/S1084952117301477?via%3Dihub (2018)
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2
Development of the aboral domain in Nematostella requires β -catenin and the opposing activities of Six3/6 and F rizzled5/8
Leclère, Lucas
;
Bause, Markus
;
Sinigaglia, Chiara
...
In: ISSN: 0951-1991 ; EISSN: 1477-9129 ; Development (Cambridge, England) ; https://hal.sorbonne-universite.fr/hal-01429678 ; Development (Cambridge, England), Company of Biologists, 2016, 143 (10), pp.1766 - 1777. ⟨10.1242/dev.120931⟩ (2016)
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3
Development of the aboral domain in Nematostella requires β-catenin and the opposing activities of Six3/6 and Frizzled5/8
Leclere, Lucas
;
Bause, Markus
;
Sinigaglia, Chiara
;
Steger, Julia
;
Rentzsch, Fabian
. - : The Company of Biologists, 2016
Abstract:
The development of the oral pole in cnidarians and the posterior pole in bilaterians is regulated by canonical Wnt signaling, whereas a set of transcription factors, including Six3/6 and FoxQ2, controls aboral development in cnidarians and anterior identity in bilaterians. However, it is poorly understood how these two patterning systems are initially set up in order to generate correct patterning along the primary body axis. Investigating the early steps of aboral pole formation in the sea anemone Nematostella vectensis, we found that, at blastula stage, oral genes are expressed before aboral genes and that Nvβ-catenin regulates both oral and aboral development. In the oral hemisphere, Nvβ-catenin specifies all subdomains except the oral-most, NvSnailA-expressing domain, which is expanded upon Nvβ-catenin knockdown. In addition, Nvβ-catenin establishes the aboral patterning system by promoting the expression of NvSix3/6 at the aboral pole and suppressing the Wnt receptor NvFrizzled5/8 at the oral pole. NvFrizzled5/8 expression thereby gets restricted to the aboral domain. At gastrula stage, NvSix3/6 and NvFrizzled5/8 are both expressed in the aboral domain, but they have opposing activities, with NvSix3/6 maintaining and NvFrizzled5/8 restricting the size of the aboral domain. At planula stage, NvFrizzled5/8 is required for patterning within the aboral domain and for regulating the size of the apical organ by modulation of a previously characterized FGF feedback loop. Our findings suggest conserved roles for Six3/6 and Frizzled5/8 in aboral/anterior development and reveal key functions for Nvβ-catenin in the patterning of the entire oral-aboral axis of Nematostella.
Keyword:
1309 Developmental Biology
;
1312 Molecular Biology
;
Anterior posterior axis
;
Apical organ
;
Axis formation
;
Cnidaria
;
Wnt signaling
URL:
https://espace.library.uq.edu.au/view/UQ:607532
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4
Serving two masters : form-function friction in syntactic amalgams
Smet, Hendrik de
;
Velde, Freek van de
In:
Studies in language <Amsterdam>. - Amsterdam : Benjamins
37 (2013) 3, 534-565
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5
Orale woordenschat en het iWNT
Van Keymeulen, Jacques
;
Devos, Magda
In:
Nederlandse taalkunde. - Amsterdam : Amsterdam University Press
16 (2011) 2, 169-179
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6
Het WNT: een Waarlijk Nuttige Tool?
Hoeksema, Jack
In:
Nederlandse taalkunde. - Amsterdam : Amsterdam University Press
16 (2011) 2, 152-159
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7
Over de Nederlandse historische woordenboeken op internet vanuit germanistisch standpunt
Gärtner, Kurt
In:
Nederlandse taalkunde. - Amsterdam : Amsterdam University Press
16 (2011) 2, 232-241
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8
Tekstinterpretatie en het WNT online
Leuvensteijn, Arjan van
In:
Nederlandse taalkunde. - Amsterdam : Amsterdam University Press
16 (2011) 2, 223-231
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OLC Linguistik
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9
Collocaties in online woordenboeken
Wouden, Ton van der
In:
Nederlandse taalkunde. - Amsterdam : Amsterdam University Press
16 (2011) 2, 180-192
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OLC Linguistik
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10
Taalkunde en elektronica
Verkuyl, H. J.
In:
Nederlandse taalkunde. - Amsterdam : Amsterdam University Press
16 (2011) 2, 160-168
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OLC Linguistik
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11
Van "acht" (507) tot "zwangerschap" (1851): historische lexicografie van boek tot internet
Mooijaart, Marijke
In:
Nederlandse taalkunde. - Amsterdam : Amsterdam University Press
16 (2011) 2, 141-151
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OLC Linguistik
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12
De (synchrone) morfologie in het WNT en daarna
Santen, Ariane van
In:
Nederlandse taalkunde. - Amsterdam : Amsterdam University Press
16 (2011) 2, 193-205
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OLC Linguistik
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13
Het WNT, lexicografie en linguistiek
Moerdijk, A.
In:
Leuvense bijdragen. - Leuven : Dep. of Linguistics of the Univ. of Leuven
72 (1983) 1, 1-36
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