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1
The Evaluation of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis: Survey of Clinical Practice Patterns in the United States
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2
Predicting Speech Intelligibility Decline in Amyotrophic Lateral Sclerosis Based on the Deterioration of Individual Speech Subsystems
Rong, Panying; Yunusova, Yana; Wang, Jun. - : Public Library of Science, 2017
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3
Predicting Speech Intelligibility Decline in Amyotrophic Lateral Sclerosis Based on the Deterioration of Individual Speech Subsystems
In: Special Education and Communication Disorders Faculty Publications (2016)
Abstract: Purpose To determine the mechanisms of speech intelligibility impairment due to neurologic impairments, intelligibility decline was modeled as a function of co-occurring changes in the articulatory, resonatory, phonatory, and respiratory subsystems. Method Sixty-six individuals diagnosed with amyotrophic lateral sclerosis (ALS) were studied longitudinally. The disease-related changes in articulatory, resonatory, phonatory, and respiratory subsystems were quantified using multiple instrumental measures, which were subjected to a principal component analysis and mixed effects models to derive a set of speech subsystem predictors. A stepwise approach was used to select the best set of subsystem predictors to model the overall decline in intelligibility. Results Intelligibility was modeled as a function of five predictors that corresponded to velocities of lip and jaw movements (articulatory), number of syllable repetitions in the alternating motion rate task (articulatory), nasal airflow (resonatory), maximum fundamental frequency (phonatory), and speech pauses (respiratory). The model accounted for 95.6%of the variance in intelligibility, among which the articulatory predictors showed the most substantial independent contribution (57.7%). Conclusion Articulatory impairments characterized by reduced velocities of lip and jaw movements and resonatory impairments characterized by increased nasal airflow served as the subsystem predictors of the longitudinal decline of speech intelligibility in ALS. Declines in maximum performance tasks such as the alternating motion rate preceded declines in intelligibility, thus serving as early predictors of bulbar dysfunction. Following the rapid decline in speech intelligibility, a precipitous decline in maximum performance tasks subsequently occurred.
URL: https://digitalcommons.unl.edu/specedfacpub/99
https://digitalcommons.unl.edu/cgi/viewcontent.cgi?article=1099&context=specedfacpub
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4
Speaking rate effects on articulatory pattern consistency in talkers with mild ALS
In: Clinical linguistics & phonetics. - London : Informa Healthcare 28 (2014) 11, 799-811
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5
Speaking rate effects on articulatory pattern consistency in talkers with mild ALS
Mefferd, Antje S.; Green, Jordan R.; Pattee, Gary. - : Informa Plc., 2014
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6
Bulbar and speech motor assessment in ALS: Challenges and future directions
In: Special Education and Communication Disorders Faculty Publications (2013)
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7
A novel fixed-target task to determine articulatory speed constraints in persons with amyotrophic lateral sclerosis
In: Journal of communication disorders. - New York, NY : Elsevier 45 (2012) 1, 35-45
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8
Tongue Movements and Their Acoustic Consequences in Amyotrophic Lateral Sclerosis
In: Special Education and Communication Disorders Faculty Publications (2012)
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9
Perceived attention allocation of listeners who transcribe the speech of speakers with amyotrophic lateral sclerosis
In: Speech communication. - Amsterdam [u.a.] : Elsevier 53 (2011) 6, 801-806
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10
A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis (ALS)
Yunusova, Yana; Green, Jordan R.; Wang, Jun. - : MyJove Corporation, 2011
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11
A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis (ALS)
In: Special Education and Communication Disorders Faculty Publications (2011)
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12
Kinematics of disease progression in bulbar ALS
In: Journal of communication disorders. - New York, NY : Elsevier 43 (2010) 1, 6-20
BLLDB
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13
Communication effectiveness of individuals with amyotrophic lateral sclerosis
In: Journal of communication disorders. - New York, NY : Elsevier 37 (2004) 3, 197-215
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14
Communication effectiveness of individuals with amyotrophic lateral sclerosis
In: Journal of communication disorders. - New York, NY : Elsevier 37 (2004) 3, 197-216
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