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All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year AND OR AND NOT All fields Title Creator / Publisher Keyword Year Sort by creator [A → Z]' creator [Z → A]' publishing year ↑ (asc)' publishing year ↓ (desc)' title [A → Z]' title [Z → A]' Simple Search Hits 1 – 13 of 13 1 Effects of healthy aging and left hemisphere stroke on statistical language learning ... Fama, Mackenzie E.; Schuler, Kathryn D.; Newport, Elissa L.. - : Taylor & Francis, 2022 BASE Show details 2 Effects of healthy aging and left hemisphere stroke on statistical language learning ... Fama, Mackenzie E.; Schuler, Kathryn D.; Newport, Elissa L.. - : Taylor & Francis, 2022 BASE Show details 3 Structural disconnection of the posterior medial frontal cortex reduces speech error monitoring McCall, Joshua D.; Vivian Dickens, J.; Mandal, Ayan S.... In: Neuroimage Clin (2022) BASE Show details 4 Experience of word-finding difficulties in aphasia (Fama et al., 2021) ... Fama, Mackenzie E.; Lemonds, Erin; Levinson, Galya. - : ASHA journals, 2021 BASE Show details 5 Experience of word-finding difficulties in aphasia (Fama et al., 2021) ... Fama, Mackenzie E.; Lemonds, Erin; Levinson, Galya. - : ASHA journals, 2021 BASE Show details 6 Brain structures and cognitive abilities important for the self-monitoring of speech errors Mandal, Ayan S.; Fama, Mackenzie E.; Skipper-Kallal, Laura M.... In: Neurobiol Lang (Camb) (2020) BASE Show details 7 Effects of age and left hemisphere lesions on audiovisual integration of speech Michaelis, Kelly; Erickson, Laura C.; Fama, Mackenzie E.... In: Brain Lang (2020) BASE Show details 8 Dissociable Mechanisms of Verbal Working Memory Revealed through Multivariate Lesion Mapping Ghaleh, Maryam; Lacey, Elizabeth H; Fama, Mackenzie E... In: Cereb Cortex (2020) BASE Show details 9 Self-reported inner speech relates to phonological retrieval ability in people with aphasia Fama, Mackenzie E.; Henderson, Mary P.; Snider, Sarah F.. - 2019 BASE Show details 10 The Subjective Experience of Inner Speech in Aphasia Is a Meaningful Reflection of Lexical Retrieval Fama, Mackenzie E.; Snider, Sarah F.; Henderson, Mary P.. - : American Speech-Language-Hearing Association, 2019 BASE Show details 11 Localization of Phonological and Semantic Contributions to Reading Dickens, J. Vivian; Fama, Mackenzie E.; DeMarco, Andrew T.; Lacey, Elizabeth H.; Friedman, Rhonda B.; Turkeltaub, Peter E.. - : Society for Neuroscience, 2019 Abstract: Reading involves the rapid extraction of sound and meaning from print through a cooperative division of labor between phonological and lexical–semantic processes. Whereas lesion studies of patients with stereotyped acquired reading deficits contributed to the notion of a dissociation between phonological and lexical–semantic reading, the neuroanatomical basis for effects of lexicality (word vs pseudoword), orthographic regularity (regular vs irregular spelling–sound correspondences), and concreteness (concrete vs abstract meaning) on reading is underspecified, particularly outside the context of strong behavioral dissociations. Support vector regression lesion–symptom mapping (LSM) of 73 left hemisphere stroke survivors (male and female human subjects) not preselected for stereotyped dissociations revealed the differential contributions of specific cortical regions to reading pseudowords (ventral precentral gyrus), regular words (planum temporale, supramarginal gyrus, ventral precentral and postcentral gyrus, and insula), and concrete words (pars orbitalis and pars triangularis). Consistent with the primary systems view of reading being parasitic on language-general circuitry, our multivariate LSM analyses revealed that phonological decoding depends on perisylvian areas subserving sound–motor integration and that semantic effects on reading depend on frontal cortex subserving control over concrete semantic representations that aid phonological access from print. As the first study to localize the differential cortical contributions to reading pseudowords, regular words, and concrete words in stroke survivors with variable reading abilities, our results provide important information on the neurobiological basis of reading and highlight the insights attainable through multivariate, process-based approaches to alexia. SIGNIFICANCE STATEMENT Whereas fMRI evidence for neuroanatomical dissociations between phonological and lexical–semantic reading is abundant, evidence from modern lesion studies establishing the differential contributions of specific brain regions to specific reading processes is lacking. Our application of multivariate lesion–symptom mapping revealed that effects of lexicality, orthographic regularity, and concreteness on reading differentially depend on areas subserving auditory–motor integration and semantic control. Phonological decoding of print relies on a dorsal perisylvian network supporting auditory and articulatory representations, with unfamiliar words relying especially on articulatory mapping. In tandem with this dorsal decoding system, anterior inferior frontal gyrus may coordinate control over concrete semantic representations that support mapping of print to sound, which is a novel potential mechanism for semantic influences on reading. Keyword: Research Articles URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607747/ https://doi.org/10.1523/JNEUROSCI.2707-18.2019 http://www.ncbi.nlm.nih.gov/pubmed/31061085 BASE Hide details 12 Subjective experience of inner speech in aphasia: Preliminary behavioral relationships and neural correlates Fama, Mackenzie E.; Hayward, William; Snider, Sarah F.. - 2016 BASE Show details 13 Group Therapy as a Social Context for Aphasia Recovery: A pilot, observational study in an acute rehabilitation hospital Fama, Mackenzie E.; Baron, Christine R.; Hatfield, Brooke. - 2016 BASE Show details

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