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1.653
Hits 1 – 20 of 33.055
1
Resilience, science, technology, engineering, and mathematics (STEM), and anger: A linguistic inquiry into the psychological processes associated with resilience in secondary school STEM learning. ...
Hall, Sophie S
;
McGill, Ross Morrison
;
Puttick, Steven
. - : Apollo - University of Cambridge Repository, 2022
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2
How bilingualism modulates selective attention in children ...
Phelps, Jacqueline
;
Attaheri, Adam
;
Bozic, Mirjana
. - : Apollo - University of Cambridge Repository, 2022
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3
Cambridge Psycholinguistic Inventory of Christian Beliefs: A registered report of construct validity, internal consistency and test-retest reliability. ...
Clackson, Kaili
;
Pohran, Nadya
;
Galli, Riccardo M
. - : Apollo - University of Cambridge Repository, 2022
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4
ЗНАЧЕНИЕ НАУЧНО-ПОПУЛЯРНОЙ СТАТЬИ ... : THE IMPORTANCE OF A POPULAR SCIENTIFIC ARTICLE ...
Кузибаева, Р.Ш.
. - : Oriental renaissance: Innovative, educational, natural and social sciences, 2022
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5
Lifelong bilingualism and mechanisms of neuroprotection in Alzheimer dementia. ...
Sala, Arianna
;
Malpetti, Maura
;
Farsad, Mohsen
. - : Apollo - University of Cambridge Repository, 2022
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6
Optionality in the Expression of Indefiniteness: A Pilot Study on Piacentine
Luca Molinari
In: Languages; Volume 7; Issue 2; Pages: 99 (2022)
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7
Approximate Entropy in Canonical and Non-Canonical Fiction
Mohseni, Mahdi
;
Redies, Christoph
;
Gast, Volker
. - : MDPI, 2022
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8
This might be the PLACE. Spelling out a covert D in Fodom spatial PPs
Mattiuzzi, Tommaso
. - 2022
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9
Speech Entrainment Improves Connectivity Between Anterior and Posterior Cortical Speech Areas in Non-Fluent Aphasia
Johnson, Lisa
;
Yourganov, Grigori
;
Basilakos, Alexandra
...
In: Neurorehabil Neural Repair (2022)
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10
Structural disconnection of the posterior medial frontal cortex reduces speech error monitoring
McCall, Joshua D.
;
Vivian Dickens, J.
;
Mandal, Ayan S.
...
In: Neuroimage Clin (2022)
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11
Human drone interaction in delivery of medical supplies: A scoping review of experimental studies
Stephan, Franziska
;
Reinsperger, Nicole
;
Grünthal, Martin
...
In: PLoS One (2022)
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12
Neuroanatomical correlations of visuospatial processing in primary progressive aphasia
Tee, Boon Lead
;
Watson Pereira, Christa
;
Lukic, Sladjana
...
In: Brain Commun (2022)
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13
Tractography of supplementary motor area projections in progressive speech apraxia and aphasia
Valls Carbo, Adrian
;
Reid, Robert I.
;
Tosakulwong, Nirubol
...
In: Neuroimage Clin (2022)
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14
Factors determining the need for general anesthesia to deliver dental treatment for adults with intellectual and developmental disabilities
Aloufi, Abdullah
;
Alatawi, Fawz
;
Hakeem, Faisal F.
...
In: Saudi J Anaesth (2022)
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15
Secondary Stroke Risk Reduction in Black Adults: a Systematic Review
Cao, Caroline
;
Jain, Nisha
;
Lu, Elaine
...
In: J Racial Ethn Health Disparities (2022)
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16
Regional Alteration within the Cerebellum and the Reorganization of the Cerebrocerebellar System following Poststroke Aphasia
Zhang, Xiaotong
;
Chen, Zhaocong
;
Li, Na
...
In: Neural Plast (2022)
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17
Neural correlates of impaired vocal feedback control in post-stroke aphasia
Behroozmand, Roozbeh
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Bonilha, Leonardo
;
Rorden, Chris
...
In: Neuroimage (2022)
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18
Aphasia recovery by language training using a brain–computer interface: a proof-of-concept study
Musso, Mariacristina
;
Hübner, David
;
Schwarzkopf, Sarah
...
In: Brain Commun (2022)
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19
Diminished preparatory physiological responses in frontotemporal lobar degeneration syndromes
Chen, Kuan-Hua
;
Hua, Alice Y.
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Toller, Gianina
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Lwi, Sandy J.
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Otero, Marcela C.
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Haase, Claudia M.
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Rankin, Katherine P.
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Rosen, Howard J.
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Miller, Bruce L.
;
Levenson, Robert W.
In: Brain Commun (2022)
Abstract:
Researchers typically study physiological responses either after stimulus onset or when the emotional valence of an upcoming stimulus is revealed. Yet, participants may also respond when they are told that an emotional stimulus is about to be presented even without knowing its valence. Increased physiological responding during this time may reflect a ‘preparation for action’. The generation of such physiological responses may be supported by frontotemporal regions of the brain that are vulnerable to damage in frontotemporal lobar degeneration. We examined preparatory physiological responses and their structural and functional neural correlate in five frontotemporal lobar degeneration clinical subtypes (behavioural variant frontotemporal dementia, n = 67; semantic variant primary progressive aphasia, n = 35; non-fluent variant primary progressive aphasia, n = 30; corticobasal syndrome, n = 32; progressive supranuclear palsy, n = 30). Comparison groups included patients with Alzheimer’s disease (n = 56) and healthy controls (n = 35). Preparatory responses were quantified as cardiac interbeat interval decreases (i.e. heart rate increases) from baseline to an ‘instruction period’, during which participants were told to watch the upcoming emotional film but not provided the film’s valence. Patients’ behavioural symptoms (apathy and disinhibition) were also evaluated via a caregiver-reported measure. Compared to healthy controls and Alzheimer’s disease, the frontotemporal lobar degeneration group showed significantly smaller preparatory responses. When comparing each frontotemporal lobar degeneration clinical subtype with healthy controls and Alzheimer’s disease, significant group differences emerged for behavioural variant frontotemporal dementia and progressive supranuclear palsy. Behavioural analyses revealed that frontotemporal lobar degeneration patients showed greater disinhibition and apathy compared to Alzheimer’s disease patients. Further, these group differences in disinhibition (but not apathy) were mediated by patients’ smaller preparatory responses. Voxel-based morphometry and resting-state functional MRI analyses revealed that across patients and healthy controls, smaller preparatory responses were associated with smaller volume and lower functional connectivity in a circuit that included the ventromedial prefrontal cortex and cortical and subcortical regions of the salience network. Diminished preparatory physiological responding in frontotemporal lobar degeneration may reflect a lack of preparation for actions that are appropriate for an upcoming situation, such as approaching or withdrawing from emotional stimuli. The ventromedial prefrontal cortex and salience network are critical for evaluating stimuli, thinking about the future, triggering peripheral physiological responses, and processing and interpreting interoceptive signals. Damage to these circuits in frontotemporal lobar degeneration may impair preparatory responses and help explain often-observed clinical symptoms such as disinhibition in these patients.
Keyword:
Original Article
URL:
http://www.ncbi.nlm.nih.gov/pubmed/35441132
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014451/
https://doi.org/10.1093/braincomms/fcac075
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20
The Recovery Mechanism of Standardized Aphasia in Intelligent Medical Treatment
Zhou, Rong
;
Lv, Ying
;
Fu, Chuhan
In: Contrast Media Mol Imaging (2022)
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