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1	The trans-ancestral genomic architecture of glycemic traits.
	Chen, J.; Spracklen, C.N.; Marenne, G....
	In: Nature genetics, vol. 53, no. 6, pp. 840-860 (2021)
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2	Global genetic differentiation of complex traits shaped by natural selection in humans.
	Guo, J.; Wu, Y.; Zhu, Z....
	In: Nature communications, vol. 9, no. 1, pp. 1865 (2018)
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3	Childhood intelligence is heritable, highly polygenic and associated with FNBP1L.
	Benyamin, B; Pourcain, B; Davis, OS; Davies, G; Hansell, NK; Brion, MJ; Kirkpatrick, RM; Cents, RA; Franić, S; Miller, MB; Haworth, CM; Meaburn, E; Price, TS; Evans, DM; Timpson, N; Kemp, J; Ring, S; McArdle, W; Medland, SE; Yang, J; Harris, SE; Liewald, DC; Scheet, P; Xiao, X; Hudziak, JJ; de Geus, EJ; Wellcome Trust Case Control Consortium 2 (WTCCC2),; Jaddoe, VW; Starr, JM; Verhulst, FC; Pennell, C; Tiemeier, H; Iacono, WG; Palmer, LJ; Montgomery, GW; Martin, NG; Boomsma, DI; Posthuma, D; McGue, M; Wright, MJ; Davey Smith, G; Deary, IJ; Plomin, R; Visscher, PM
	In: Mol Psychiatry , 19 (2) 253 - 258. (2014) (2014)
	Abstract: Intelligence in childhood, as measured by psychometric cognitive tests, is a strong predictor of many important life outcomes, including educational attainment, income, health and lifespan. Results from twin, family and adoption studies are consistent with general intelligence being highly heritable and genetically stable throughout the life course. No robustly associated genetic loci or variants for childhood intelligence have been reported. Here, we report the first genome-wide association study (GWAS) on childhood intelligence (age range 6-18 years) from 17,989 individuals in six discovery and three replication samples. Although no individual single-nucleotide polymorphisms (SNPs) were detected with genome-wide significance, we show that the aggregate effects of common SNPs explain 22-46% of phenotypic variation in childhood intelligence in the three largest cohorts (P=3.9 × 10(-15), 0.014 and 0.028). FNBP1L, previously reported to be the most significantly associated gene for adult intelligence, was also significantly associated with childhood intelligence (P=0.003). Polygenic prediction analyses resulted in a significant correlation between predictor and outcome in all replication cohorts. The proportion of childhood intelligence explained by the predictor reached 1.2% (P=6 × 10(-5)), 3.5% (P=10(-3)) and 0.5% (P=6 × 10(-5)) in three independent validation cohorts. Given the sample sizes, these genetic prediction results are consistent with expectations if the genetic architecture of childhood intelligence is like that of body mass index or height. Our study provides molecular support for the heritability and polygenic nature of childhood intelligence. Larger sample sizes will be required to detect individual variants with genome-wide significance.
	Keyword: Adolescent; Carrier Proteins; Child; Cohort Studies; European Continental Ancestry Group; Female; Genome-Wide Association Study; Genotyping Techniques; Heritable; Humans; Intelligence; Intelligence Tests; Male; Multifactorial Inheritance; Phenotype; Polymorphism; Quantitative Trait; Single Nucleotide; Software
	URL: http://discovery.ucl.ac.uk/1390679/
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4	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
	Sabatti, C; Service, SK; Hartikainen, AL...
	In: Symplectic Elements at Oxford ; Europe PubMed Central ; PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) ; Web of Science (Lite) (http://apps.webofknowledge.com/summary.do) ; Scopus (http://www.scopus.com/home.url) ; CrossRef (2009)
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5	Generalist genes and the Internet generation: etiology of learning abilities by web testing at age 10.
	Davis, OS; Kovas, Y; Harlaar, N...
	In: Genes Brain Behav , 7 (4) pp. 455-462. (2008) (2008)
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6	Heritable risk factors associated with language impairments.
	Barry, JG; Yasin, I; Bishop, DV
	In: Symplectic Elements at Oxford ; Europe PubMed Central ; PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) ; Web of Science (Lite) (http://apps.webofknowledge.com/summary.do) ; Scopus (http://www.scopus.com/home.url) ; CrossRef ; ORA review team (2007)
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7	A genomewide scan identifies two novel loci involved in specific language impairment.
	In: Symplectic Elements at Oxford ; Europe PubMed Central ; PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) ; Web of Science (Lite) (http://apps.webofknowledge.com/summary.do) ; Scopus (http://www.scopus.com/home.url) ; ORA review team (2002)
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8	Independent genome-wide scans identify a chromosome 18 quantitative-trait locus influencing dyslexia.
	Fisher, SE; Francks, C; Marlow, AJ...
	In: Symplectic Elements at Oxford ; Europe PubMed Central ; PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) ; Web of Science (Lite) (http://apps.webofknowledge.com/summary.do) ; Scopus (http://www.scopus.com/home.url) ; CrossRef (2002)
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9	A quantitative-trait locus on chromosome 6p influences different aspects of developmental dyslexia.
	Fisher, SE; Marlow, AJ; Lamb, J...
	In: Symplectic Elements at Oxford ; Europe PubMed Central ; PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) ; Web of Science (Lite) (http://apps.webofknowledge.com/summary.do) ; Scopus (http://www.scopus.com/home.url) ; CrossRef (1999)
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10	A genome-wide search strategy for identifying quantitative trait loci involved in reading and spelling disability (developmental dyslexia).
	Fisher, SE; Stein, JF; Monaco, AP
	In: Symplectic Elements at Oxford ; Europe PubMed Central ; PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) ; Web of Science (Lite) (http://apps.webofknowledge.com/summary.do) ; Scopus (http://www.scopus.com/home.url) ; CrossRef (1999)
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