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1
Atypical Callosal Morphology in Children with Speech Sound Disorder
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2
The Sexual Dimorphism of Broca’s Region: More Gray Matter in Female Brains in Brodmann Areas 44 and 45
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3
Shape analysis of the corpus callosum in Alzheimer's disease and frontotemporal lobar degeneration subtypes
In: Journal of Alzheimer's Disease (2015)
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4
Shape analysis of the corpus callosum in Alzheimer's disease and frontotemporal lobar degeneration subtypes
In: Journal of Alzheimer's Disease (2015)
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5
Structural and Functional Reorganization of the Corpus Callosum between the Age of 6 and 8 Years
Westerhausen, René; Luders, Eileen; Specht, Karsten. - : Oxford University Press, 2011
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6
Structural and Functional Reorganization of the Corpus Callosum between the Age of 6 and 8 Years
Abstract: The establishment of an efficient exchange of information between the cerebral hemispheres is of crucial importance in the developing functionally lateralized brain. The corpus callosum, the major connection between the cerebral hemispheres, grows constantly throughout childhood and adolescence. However, behavioral studies suggest the existence of a critical time period for callosal functional development starting around the age of 6 years. In the present longitudinal study, examining a cohort of 20 children at the age of 6 and 8 years, we assessed the relationship between structural and functional callosal development during this time period. The structural development was quantified by calculating the increase in callosal thickness using a shape-based computational analysis of the mid-sagittal corpus callosum as obtained with magnetic resonance imaging. The functional development was assessed with a speech discrimination task based on the dichotic presentation of consonant–vowel syllables. The statistical analysis revealed that children whose callosal isthmus increased in thickness over the course of 2 years showed a decrease in interhemispheric information transfer. However, children exhibiting a decrease in isthmus thickness revealed an increase in information transfer. These results might indicate a refinement process of the callosal connections to optimize the neuronal communication between the developing cerebral hemispheres.
Keyword: Articles
URL: http://www.ncbi.nlm.nih.gov/pubmed/20847151
https://doi.org/10.1093/cercor/bhq165
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077426
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7
Structural and Functional Reorganization of the Corpus Callosum between the Age of 6 and 8 Years
Westerhausen, René; Luders, Eileen; Specht, Karsten. - : Oxford University Press, 2010
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