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Multimodal Neural and Behavioral Data Predict Response to Rehabilitation in Chronic Poststroke Aphasia
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In: Stroke (2022)
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Selective Functional Network Changes Following tDCS-Augmented Language Treatment in Primary Progressive Aphasia
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In: Front Aging Neurosci (2021)
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Predicting language recovery in post-stroke aphasia using behavior and functional MRI
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In: Sci Rep (2021)
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Distinct Neural Substrates Support Phonological and Orthographic Working Memory: Implications for Theories of Working Memory
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Distinct Neural Substrates Support Phonological and Orthographic Working Memory: Implications for Theories of Working Memory
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In: Front Neurol (2021)
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A Tool for Automatic Scoring of Spelling Performance
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In: J Speech Lang Hear Res (2020)
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Reading Proficiency Influences the effects of Transcranial Direct Current Stimulation: Evidence from Selective Modulation of Dorsal and Ventral Pathways of reading in Bilinguals
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In: Brain Lang (2020)
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Different patterns of functional network re-organization across the variants of primary progressive aphasia: A graph theoretic analysis
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In: Neurobiol Aging (2020)
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Reliability of BOLD signals in chronic stroke-induced aphasia ...
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Language network re-organization associated with word- and sentence-level language interventions in chronic aphasia ...
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The use of spelling for variant classification in primary progressive aphasia: Theoretical and practical implications
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In: Neuropsychologia (2019)
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Local response heterogeneity indexes experience-based neural differentiation in reading
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Learning in complex, multi-component cognitive systems: Different learning challenges within the same system
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In: J Exp Psychol Learn Mem Cogn (2018)
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Right hemisphere grey matter volume and language functions in stroke aphasia
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Intrahemispheric Perfusion in Chronic Stroke-Induced Aphasia
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Right Hemisphere Grey Matter Volume and Language Functions in Stroke Aphasia
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Intrahemispheric Perfusion in Chronic Stroke-Induced Aphasia
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Thompson, Cynthia K.; Walenski, Matthew; Chen, YuFen; Caplan, David; Kiran, Swathi; Rapp, Brenda; Grunewald, Kristin; Nunez, Mia; Zinbarg, Richard; Parrish, Todd B.. - : Hindawi, 2017
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Abstract:
Stroke-induced alterations in cerebral blood flow (perfusion) may contribute to functional language impairments and recovery in chronic aphasia. Using MRI, we examined perfusion in the right and left hemispheres of 35 aphasic and 16 healthy control participants. Across 76 regions (38 per hemisphere), no significant between-subjects differences were found in the left, whereas blood flow in the right was increased in the aphasic compared to the control participants. Region-of-interest (ROI) analyses showed a varied pattern of hypo- and hyperperfused regions across hemispheres in the aphasic participants; however, there were no significant correlations between perfusion values and language abilities in these regions. These patterns may reflect autoregulatory changes in blood flow following stroke and/or increases in general cognitive effort, rather than maladaptive language processing. We also examined blood flow in perilesional tissue, finding the greatest hypoperfusion close to the lesion (within 0–6 mm), with greater hypoperfusion in this region compared to more distal regions. In addition, hypoperfusion in this region was significantly correlated with language impairment. These findings underscore the need to consider cerebral perfusion as a factor contributing to language deficits in chronic aphasia as well as recovery of language function.
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Keyword:
Research Article
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URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357554/ https://doi.org/10.1155/2017/2361691
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Right Hemisphere Grey Matter Volume and Language Functions in Stroke Aphasia
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