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Spectrum of neuropsychiatric symptoms in chronic post-stroke aphasia
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In: World J Psychiatry (2022)
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Impact of literacy on the functional connectivity of vision and language related networks
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In: ISSN: 1053-8119 ; EISSN: 1095-9572 ; NeuroImage ; https://hal.sorbonne-universite.fr/hal-02551991 ; NeuroImage, Elsevier, 2020, 213, pp.116722. ⟨10.1016/j.neuroimage.2020.116722⟩ (2020)
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Neurocognitive signatures of phonemic sequencing in expert backward speakers
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In: Sci Rep (2020)
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Pharmacotherapy of Traumatic Childhood Aphasia: Beneficial Effects of Donepezil Alone and Combined With Intensive Naming Therapy
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In: Front Pharmacol (2020)
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Developmental Dynamic Dysphasia: Are Bilateral Brain Abnormalities a Signature of Inefficient Neural Plasticity?
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Neurocognitive signatures of phonemic sequencing in expert backward speakers
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Is the emergence of speech errors in chronic post-stroke aphasia a result of ongoing compensatory brain plasticity mechanisms?
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Neural signatures of treatment-induced benefits in apathy and depression amongst persons with aphasia
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Towards a tailored approach to neuroplasticity enhancement based on brain and behavioral predictors of language learning success
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Abstract:
Individual differences in the functional and morphological architecture of the dorsal and ventral language pathways may explain part of the variability observed in the ability to learn new words in healthy population and in language recovery of persons with aphasia (PWA). The traditional gold-standard of aphasia rehabilitation is speech and language therapy (SLT), yet in many cases its effectiveness is limited and aphasic subjects are left with enduring deficits. More recent studies suggest that benefits of SLT can be boosted by the use of additional therapeutic approaches such as transcranial direct current stimulation (tDCS). The present project seeks to identify brain and cognitive predictors of treatment response that guide the choice of the language pathway (i.e. dorsal or ventral) and hemisphere (left or right) that must be potentiated to maximize individual benefits. For this, the implication of the dorsal and ventral pathways will be modulated with two validated word-learning tasks: phonological word-learning task and contextual word-learning task. Further, the activity of the left or right cerebral hemispheres will be modulated by using 3different tDCS conditions. This project will be implemented through two studies in two different samples: (i) 30 healthy adults, and (ii) 10 PWA. Each subject will participate in 3 sessions separated by a week. In each session, subjects will receive a different tDCS stimulation condition and will be required to perform the two learning tasks. A magnetic resonance imaging session will be acquired at baseline to obtain structural and functional information. The results of this project will provide helpful hints for making decision in the selection of therapeutic algorithms for tDCS as well as for the selection of tailor-made SLT for aphasic individuals. ; Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.
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Keyword:
Afasia; Aphasia; Brain plasticity; Language learning; Lenguas - Estudio y enseñanza; Neuroimaging; Neuroplasticidad; TDCS
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URL: https://hdl.handle.net/10630/20630
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Language as a Threat: Multimodal Evaluation and Interventions for Overwhelming Linguistic Anxiety in Severe Aphasia
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Beneficial effects of pharmacological treatment in post-stroke dynamic aphasia: a behavioural and neuroimaging study
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Ecolalia mitigada y conducta de aproximación: plasticidad compensatoria en los circuitos cerebrales de lenguaje
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Aphasia with anatomical isolation of the language area: A reanalysis on the light of modern neuroimaging techniques
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Thinking on Treating Echolalia in Aphasia: Recommendations and Caveats for Future Research Directions
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Language Learning Variability within the Dorsal and Ventral Streams as a Cue for Compensatory Mechanisms in Aphasia Recovery
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A reappraisal of echolalia in aphasia: A case-series study with multimodal neuroimaging
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Overrepresentation of verbal repetition deficits in aphasic men with stroke: A systematic literature review and meta-analysis
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Attentional effects on rule extraction and consolidation from speech.
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