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Family history of FXTAS is associated with age-related cognitive-linguistic decline among mothers with the FMR1 premutation.
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In: Journal of neurodevelopmental disorders, vol 14, iss 1 (2022)
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Increased connectivity among sensory and motor regions during visual and audiovisual speech perception
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In: Open Access Publications (2022)
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Cross-cultural adaptation into French and validation of the SCAR-Q questionnaire ; Cross-cultural adaptation into French and validation of the SCAR-Q questionnaire.
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In: ISSN: 0962-9343 ; EISSN: 1573-2649 ; Quality of Life Research ; https://hal-amu.archives-ouvertes.fr/hal-03623447 ; Quality of Life Research, Springer Verlag, 2021, 30 (4), pp.1225-1231. ⟨10.1007/s11136-020-02719-8⟩ (2021)
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White matter disconnectivity fingerprints causally linked to dissociated forms of alexia
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In: ISSN: 2399-3642 ; Communications Biology ; https://hal.umontpellier.fr/hal-03634907 ; Communications Biology, Nature Publishing Group, 2021, 4 (1), pp.1413. ⟨10.1038/s42003-021-02943-z⟩ (2021)
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Drug induced stuttering: pharmacovigilance data ; Drug induced stuttering: pharmacovigilance data.
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In: ISSN: 1474-0338 ; EISSN: 1744-764X ; Expert Opinion on Drug Safety ; https://hal.archives-ouvertes.fr/hal-03474488 ; Expert Opinion on Drug Safety, Informa Healthcare, 2021, 20 (3), pp.373-378. ⟨10.1080/14740338.2021.1867101⟩ (2021)
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Neural dynamics of semantic categorization in semantic variant of primary progressive aphasia.
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Borghesani, V; Dale, CL; Lukic, S; Hinkley, Lbn; Lauricella, M; Shwe, W; Mizuiri, D; Honma, S; Miller, Z; Miller, B; Houde, JF; Gorno-Tempini, ML; Nagarajan, SS. - : eScholarship, University of California, 2021
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Abstract:
Semantic representations are processed along a posterior-to-anterior gradient reflecting a shift from perceptual (e.g., it has eight legs) to conceptual (e.g., venomous spiders are rare) information. One critical region is the anterior temporal lobe (ATL): patients with semantic variant primary progressive aphasia (svPPA), a clinical syndrome associated with ATL neurodegeneration, manifest a deep loss of semantic knowledge. We test the hypothesis that svPPA patients perform semantic tasks by over-recruiting areas implicated in perceptual processing. We compared MEG recordings of svPPA patients and healthy controls during a categorization task. While behavioral performance did not differ, svPPA patients showed indications of greater activation over bilateral occipital cortices and superior temporal gyrus, and inconsistent engagement of frontal regions. These findings suggest a pervasive reorganization of brain networks in response to ATL neurodegeneration: the loss of this critical hub leads to a dysregulated (semantic) control system, and defective semantic representations are seemingly compensated via enhanced perceptual processing.
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Keyword:
2.1 Biological and endogenous factors; Aged; anterior temporal lobe; Aphasia; Basic Behavioral and Social Science; Behavioral and Social Science; Biochemistry and Cell Biology; Brain Disorders; Clinical Research; Female; human; Humans; magnetoencephalography; Male; Mental Health; Middle Aged; Nerve Degeneration; Neurons; neuroscience; Neurosciences; Primary Progressive; primary progressive aphasia; semantic categorization; semantic dementia; semantic variant ppa; Semantics; Temporal Lobe
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URL: https://escholarship.org/uc/item/6s23q3d9
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A Bayesian optimization approach for rapidly mapping residual network function in stroke. ...
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Cross-linguistic variation in word-initial cluster production in adult and child language: evidence from English and Norwegian. ...
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Age-related differences in the neural bases of phonological and semantic processes in the context of task-irrelevant information.
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Influence of encoding difficulty, word frequency, and phonological regularity on age differences in word naming.
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Age-related differences in the neural bases of phonological and semantic processes.
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Age-related differences in resolving semantic and phonological competition during receptive language tasks.
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Predictive Neural Computations Support Spoken Word Recognition: Evidence from MEG and Competitor Priming. ...
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Sustained neural rhythms reveal endogenous oscillations supporting speech perception. ...
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Language networks in aphasia and health: A 1000 participant activation likelihood estimation meta-analysis. ...
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Validation of the Portuguese version of the Evidence-Based Practice Questionnaire
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A Bayesian optimization approach for rapidly mapping residual network function in stroke.
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Predictive Neural Computations Support Spoken Word Recognition: Evidence from MEG and Competitor Priming.
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Cross-linguistic variation in word-initial cluster production in adult and child language: evidence from English and Norwegian.
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DYT-TUBB4A (DYT4 Dystonia): New Clinical and Genetic Observations.
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In: Neurology, vol. 96, no. 14, pp. e1887-e1897 (2021)
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