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Hits 41 – 60 of 87
41
Treatment for Morphosyntactic Deficits: From Specific Strategies to a Holistic Approach
Proctor-Williams, Kerry
In: ETSU Faculty Works (2014)
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42
Reflective practice and professional knowledge: A grounded theory study of Speech-Language Pathologists working in head and neck cancer rehabilitation
Caty, Marie-Eve
In: Electronic Thesis and Dissertation Repository (2014)
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43
Audiology Services at Remote Area Medical Expeditions in Southern Appalachia
Fagelson, Marc A.
In: ETSU Faculty Works (2013)
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44
Genome-Wide Analysis of Translational Control in Tuberous Sclerosis Complex
Qian, Shu-Bing
In: DTIC (2013)
Abstract:
The TSC1/TSC2 complex integrates multiple cues to regulate protein translation and cell growth via mammalian target of rapamycin complex I (mTORC1). Loss of TSC functions leads to constitutive activation of mTORC1 and uncontrolled mRNA translation. The goal of this res earch project to elucidate cis -regulatory elements and trans -acting factors in TSC-mTORC1- mediated translational regulation. We have discovered that the stress -induced preferential translation of Hsp70 mRNA is deficient in cells lacking TSC2. This finding provides a plausible mechanism about how persistent mTOR signaling favors the development of various pathologies of TSC by attenuating stress resistance. We recently discovered that TSC -mTORC1 increased the yield of protein synthesis at the expense of protein quality. By harnessing the power of ribosome profiling, we also discovered post-initiation ribosomal pausing that is subject to TSC-mTORC1 regulation. In addition, we have established a novel approach called Global Translation Initiation sequencing (GTI-seq) to investigate alternative translation. These studies are significant because TSC-mTORC1-controlled alternative translation initiation has never been defined. ; The original document contains color images.
Keyword:
*GENOME
;
*STRESS(PHYSIOLOGY)
;
*TUBEROUS SCLEROSIS
;
ATTENUATION
;
CELLS(BIOLOGY)
;
Genetic Engineering and Molecular Biology
;
GENOME-WIDE
;
HIGH THROUGHPUT
;
MAMMALS
;
Medicine and Medical Research
;
PATHOLOGY
;
PROTEIN HOMEOSTASIS
;
RIBOSOME
;
Stress Physiology
;
SYNTHESIS(CHEMISTRY)
;
TRANSLATION
URL:
http://oai.dtic.mil/oai/oai?&verb=getRecord&metadataPrefix=html&identifier=ADA584195
http://www.dtic.mil/docs/citations/ADA584195
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45
Living successfully with aphasia during the first year post stroke
Grohn, Brooke
. - : The University of Queensland, School of Health & Rehabilitation Sciences, 2013
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46
The Magnetic Resonance Imaging subset of the mngu0 articulatory corpus
Gray, Calum
;
Steiner, Ingmar
;
Marshall, Ian
...
In: ISSN: 0001-4966 ; EISSN: 1520-8524 ; Journal of the Acoustical Society of America ; https://hal.inria.fr/hal-00661082 ; Journal of the Acoustical Society of America, Acoustical Society of America, 2012, 131 (2), pp.106-111. ⟨10.1121/1.3675459⟩ (2012)
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47
" L'ellipse comme procédé néologique dans la prose médicale du français préclassique "
Mecking, Volker
In: https://halshs.archives-ouvertes.fr/halshs-00750593 ; 2012 (2012)
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48
Preliminary Data on Prevention and Treatment of Voice Problems in Student Teachers
Nanjundeswaran (Guntupalli), Chaya D.
;
Li, Nicole Y.K.
;
Chan, Karen M.K.
...
In: ETSU Faculty Works (2012)
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49
Mild Traumatic Brain Injury and Associated Effects on the Auditory System
Schairer, Kim S.
In: ETSU Faculty Works (2012)
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50
Can simulation replace part of clinical time? Two parallel randomised controlled trials
Watson, Kathryn
;
Wright, Anthony
;
Morris, Norman
. - : Wiley-Blackwell Puiblishing, 2012
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51
The use of standardised patients in the clinical education of speech pathology students
Hill, Anne Elizabeth
. - : The University of Queensland, School of Health & Rehabilitation Sciences, 2012
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52
Salud y Saludos: The E-News of the College of Health Sciences
College of Health Sciences
In: College of Health Sciences (2012)
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53
The Effect of Static and Dynamic Visual Gestures on Stuttering Inhibition
Guntupalli, Vijaya K.
;
Nanjundeswaran (Guntupalli), Chaya D.
;
Kalinowski, Joseph
...
In: ETSU Faculty Works (2011)
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54
Past Speech Therapy Experiences of Individuals Exploring a New Stuttering Treatment
Guntupalli, Vijaya K.
;
Nanjundeswaran (Guntupalli), Chaya D.
;
Kalinowski, Joseph
...
In: ETSU Faculty Works (2011)
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55
Effects of Stimulus and Recording Parameters on the Air Conduction Ocular Vestibular Evoked Myogenic Potential
Murnane, Owen D.
;
Akin, Faith W.
;
Kelly, J. Kip
...
In: ETSU Faculty Works (2011)
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56
Head Injury and Blast Exposure: Vestibular Consequences
Akin, Faith W.
;
Murnane, Owen D.
In: ETSU Faculty Works (2011)
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57
The Effect of Age on the Vestibular Evoked Myogenic Potential and Sternocleidomastoid Muscle Tonic Electromyogram Level
Akin, Faith W.
;
Murnane, Owen D.
;
Tampas, Joanna W.
...
In: ETSU Faculty Works (2011)
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58
Normative Data for the Subjective Visual Vertical Test during Centrifugation
Akin, Faith W.
;
Murnane, Owen D.
;
Pearson, Amber
...
In: ETSU Faculty Works (2011)
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59
Dysphagia following thermal burn injury: Clinical risk factors, anatomical and physiological characteristics and road to resolution and recovery
Anna Rumbach
. - : The University of Queensland, School of Health and Rehabilitation Sciences, 2011
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60
Nova Scotia Medical Bulletin 5(4), 1926
Medical Society of Nova Scotia
. - : Halifax, Medical Society of Nova Scotia, 2010
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