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1
Clinical Correlates of Alzheimer's Disease Cerebrospinal Fluid Analytes in Primary Progressive Aphasia
Norise, Catherine; Ungrady, Molly; Halpin, Amy. - : Frontiers Media S.A., 2019
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2
A Longitudinal Study of Speech Production in Primary Progressive Aphasia and Behavioral Variant Frontotemporal Dementia
In: Brain Lang (2019)
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3
Longitudinal progression of grey matter atrophy in non-amnestic Alzheimer’s disease
In: Brain (2019)
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4
18F-Flortaucipir PET/MRI Correlations in Nonamnestic and Amnestic Variants of Alzheimer Disease
Nasrallah, Ilya M.; Chen, Yin Jie; Hsieh, Meng-Kang. - : Society of Nuclear Medicine, 2018
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5
Clinical marker for Alzheimer disease pathology in logopenic primary progressive aphasia
Giannini, Lucia A.A.; Irwin, David J.; McMillan, Corey T.. - : Lippincott Williams & Wilkins, 2017
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6
Tau PET Imaging Predicts Cognition in Atypical Variants of Alzheimer’s Disease
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7
Neocortical Origin and Progression of Grey Matter Atrophy In Non-Amnestic Alzheimer’s Disease
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8
Neural Correlates of Verbal Episodic Memory and Lexical Retrieval in Logopenic Variant Primary Progressive Aphasia
Win, Khaing T.; Pluta, John; Yushkevich, Paul. - : Frontiers Media S.A., 2017
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9
Dissociation of Quantifiers and Object Nouns in Speech in Focal Neurodegenerative Disease
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10
ARTERIAL SPIN LABELING PERFUSION PREDICTS LONGITUDINAL DECLINE IN SEMANTIC VARIANT PRIMARY PROGRESSIVE APHASIA
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11
How the brain learns how few are “many”: An fMRI study of the flexibility of quantifier semantics
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12
Beyond words: Pragmatic inference in behavioral variant of frontotemporal degeneration
Abstract: When the message of a speaker goes beyond the literal or logical meaning of the sentences used, a pragmatic inference is required to understand the complete meaning of an utterance. Here we study one example of pragmatic inference, called scalar implicature. Such an inference is required when a weaker term “some” is used in a sentence like “Some of the students passed the exam” because the speaker presumably had a reason not to use a stronger term like “all”. We investigated the comprehension of scalar implicatures in a group of 17 non-aphasic patients with behavioral variant frontotemporal degeneration (bvFTD) in order to test the contribution of non-linguistic decision-making ability and the role of prefrontal cortex in supporting the computation of pragmatic inferences. The results of two experiments point to a deficit in producing alternative interpretations beyond a logical reading. bvFTD patients thus prefer the narrowly literal or logical interpretation of a scalar term when they must generate a possible alternative interpretation by themselves, but patients prefer a pragmatic reading when offered a choice between the logical and the pragmatic interpretation of the same sentence. An imaging analysis links bvFTD patients’ spontaneous tendency toward a narrowly logical interpretation with atrophy in ventromedial prefrontal cortex. Our findings are consistent with the pragmatic tolerance hypothesis, which proposes that difficulty generating alternative interpretations of an utterance, rather than a frank inability to compute an inference, affects the comprehension of a scalar term.
Keyword: Article
URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546570/
http://www.ncbi.nlm.nih.gov/pubmed/26150205
https://doi.org/10.1016/j.neuropsychologia.2015.07.002
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13
Processing ambiguity in a linguistic context: decision-making difficulties in non-aphasic patients with behavioral variant frontotemporal degeneration
Spotorno, Nicola; Healey, Meghan; McMillan, Corey T.. - : Frontiers Media S.A., 2015
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14
Relating brain anatomy and cognitive ability using a multivariate multimodal framework
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15
Deficits in sentence expression in amyotrophic lateral sclerosis
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16
The relative contributions of frontal and parietal cortex for generalized quantifier comprehension
Olm, Christopher A.; McMillan, Corey T.; Spotorno, Nicola. - : Frontiers Media S.A., 2014
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17
Impairment of script comprehension in Lewy body spectrum disorders
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 125 (2013) 3, 330-343
OLC Linguistik
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18
Comparative semantic profiles in semantic dementia and Alzheimer's disease
Libon, David J.; Rascovsky, Katya; Powers, John. - : Oxford University Press, 2013
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19
White Matter Disease Correlates with Lexical Retrieval Deficits in Primary Progressive Aphasia
Powers, John P.; McMillan, Corey T.; Brun, Caroline C.. - : Frontiers Media S.A., 2013
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20
Sparse canonical correlation analysis relates network-level atrophy to multivariate cognitive measures in a neurodegenerative population
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