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1
Dynamic functional brain network connectivity during pseudoword processing relates to children’s reading skill
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2
Unsuspected Alzheimer disease in a patient with Multiple sclerosis and progressive aphasia.
In: Multiple sclerosis and related disorders, vol. 45, pp. 102349 (2020)
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3
Focal Hypoperfusion in Acute Ischemic Stroke Perfusion CT: Clinical and Radiologic Predictors and Accuracy for Infarct Prediction.
In: AJNR. American journal of neuroradiology, vol. 40, no. 3, pp. 483-489 (2019)
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4
Diagnostic utility of FDG-PET in the differential diagnosis between different forms of primary progressive aphasia
In: ISSN: 1619-7070 ; European Journal of Nuclear Medicine and Molecular Imaging, Vol. 45, No 9 (2018) pp. 1526-1533 (2018)
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5
Linking Entropy at Rest with the Underlying Structural Connectivity in the Healthy and Lesioned Brain.
In: Cerebral cortex, vol. 28, no. 8, pp. 2948-2958 (2018)
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6
High-Resolution, Non-Invasive Imaging of Upper Vocal Tract Articulators Compatible with Human Brain Recordings.
In: PloS one, vol 11, iss 3 (2016)
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7
Effects of HIV and childhood trauma on brain morphometry and neurocognitive function.
In: Journal of neurovirology, vol 22, iss 2 (2016)
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8
Functional Anatomy of Recognition of Chinese Multi-Character Words: Convergent Evidence from Effects of Transposable Nonwords, Lexicality, and Word Frequency
Yu, Xi; Lin, Nan; Zhang, Mingxia. - : Public Library of Science, 2016
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9
The Yin and the Yang of Prediction: An fMRI Study of Semantic Predictive Processing
Weber, Kirsten; Lau, Ellen F.; Stillerman, Benjamin. - : Public Library of Science, 2016
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10
Partly segregated cortico-subcortical pathways support phonologic and semantic verbal fluency: A lesion study.
In: Neuroscience, vol. 329, pp. 275-283 (2016)
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11
The angular gyrus: multiple functions and multiple subdivisions.
In: Neuroscientist , 19 (1) 43 - 61. (2013) (2013)
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12
Sylvian fissure and parietal anatomy in children with autism spectrum disorder
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13
Symptom profile of DSM-IV major and minor depressive disorders in first-ever stroke patients
Spalletta, G; Ripa, A; Caltagirone, C. - : Lippincott, Williams & Wilkins, 2005
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14
Auditory lexical decision, categorical perception, and FM direction discrimination differentially engage left and right auditory cortex
In: ISSN: 0028-3932 ; Neuropsychologia, Vol. 42, No 2 (2004) pp. 183-200 (2004)
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15
Sensitivity to prosodic structure in left- and right-hemisphere-damaged individuals
In: http://www.sciencedirect.com/science/article/pii/S0093934X03001093?via%3Dihub (2003)
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16
Chronic schizophrenia as a brain misconnection syndrome: a white matter voxel-based morphometry study
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17
The BDNF Val66Met Polymorphism Influences Reading Ability and Patterns of Neural Activation in Children.
Abstract: Understanding how genes impact the brain's functional activation for learning and cognition during development remains limited. We asked whether a common genetic variant in the BDNF gene (the Val66Met polymorphism) modulates neural activation in the young brain during a critical period for the emergence and maturation of the neural circuitry for reading. In animal models, the bdnf variation has been shown to be associated with the structure and function of the developing brain and in humans it has been associated with multiple aspects of cognition, particularly memory, which are relevant for the development of skilled reading. Yet, little is known about the impact of the Val66Met polymorphism on functional brain activation in development, either in animal models or in humans. Here, we examined whether the BDNF Val66Met polymorphism (dbSNP rs6265) is associated with children's (age 6-10) neural activation patterns during a reading task (n = 81) using functional magnetic resonance imaging (fMRI), genotyping, and standardized behavioral assessments of cognitive and reading development. Children homozygous for the Val allele at the SNP rs6265 of the BDNF gene outperformed Met allele carriers on reading comprehension and phonological memory, tasks that have a strong memory component. Consistent with these behavioral findings, Met allele carriers showed greater activation in reading-related brain regions including the fusiform gyrus, the left inferior frontal gyrus and left superior temporal gyrus as well as greater activation in the hippocampus during a word and pseudoword reading task. Increased engagement of memory and spoken language regions for Met allele carriers relative to Val/Val homozygotes during reading suggests that Met carriers have to exert greater effort required to retrieve phonological codes. ; P01 HD001994, P50 HD052120, R01 HD048830, R03 HD053409 ; This NIH-funded author manuscript originally appeared in PubMed Central at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995017.
Keyword: Brain-Derived Neurotrophic Factor/genetics; Child; Cognition/physiology; Female; Frontal Lobe/diagnostic imaging; Frontal Lobe/physiology; Gene Frequency; Genotype; Hippocampus/diagnostic imaging; Hippocampus/physiology; Humans; Magnetic Resonance Imaging; Male; Memory/physiology; Neurons/physiology; Polymorphism; Reading; Single Nucleotide/genetics
URL: https://doi.org/10.1371/journal.pone.0157449
http://diginole.lib.fsu.edu/islandora/object/fsu%3A600786/datastream/TN/view/BDNF%20Val66Met%20Polymorphism%20Influences%20Reading%20Ability%20and%20Patterns%20of%20Neural%20Activation%20in%20Children.jpg
http://purl.flvc.org/fsu/fd/FSU_pmch_27551971
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