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1
Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia.
In: Brain communications, vol 1, iss 1 (2019)
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2
Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia.
In: Brain communications, vol 1, iss 1 (2019)
Abstract: An increased prevalence of dyslexia has been observed in individuals diagnosed with primary progressive aphasia, most notably the logopenic variant primary progressive aphasia. The underlying pathology most commonly associated with logopenic variant primary progressive aphasia is Alzheimer's disease. In this clinical case report series, we describe the neuropathological findings of three patients with logopenic variant primary progressive aphasia and developmental dyslexia, each demonstrating a pattern of cerebrocortical microdysgenesis, reminiscent of findings first reported in dyslexic individuals, alongside expected Alzheimer's disease pathology. Neurodevelopmental and most severe Alzheimer's disease pathological changes overlapped within perisylvian brain regions, areas associated with phonological deficits in both logopenic variant primary progressive aphasia and dyslexia. These three cases with pathological findings support the hypothesis that early-life neurodevelopmental changes might influence later-life susceptibility to neurodegenerative disease and could contribute to non-amnestic, early age-of-onset presentations of Alzheimer's disease. Larger studies investigating neurobiological vulnerability across the lifespan are needed.
Keyword: 2.1 Biological and endogenous factors; Acquired Cognitive Impairment; Aging; Alzheimer's Disease; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD); Alzheimer’s disease; Aphasia; brain development; Brain Disorders; cortical developmental abnormalities; Dementia; dyslexia; Neurodegenerative; Neurological; Neurosciences; primary progressive aphasia
URL: https://escholarship.org/uc/item/7v97r987
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3
The concept of regularization: resolving the problem of surface dyslexia in semantic variant primary progressive aphasia across different languages
Billette, Ornella V.; Preib, Daniel; Nestor, Peter J.. - : American Psychological Association, 2019
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4
Dyslexia in adolescence : global perspectives
Anderson, Peggy L. (Herausgeber); Meier-Hedde, Regine (Herausgeber). - London : Routledge, 2017
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UB Frankfurt Linguistik
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5
Case studies in communication disorders
Cummings, Louise. - Cambridge : Cambridge University Press, 2016
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UB Frankfurt Linguistik
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6
The representation of language in the brain : in honour of John C. Marshall
Code, Christopher (Herausgeber); Marshall, John C. (Gefeierter). - Hove [u.a.] : Psychology Press, 2015
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UB Frankfurt Linguistik
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7
Language disorders in multilingual and multicultural populations
In: Annual review of applied linguistics. - Cambridge, Mass. [u.a.] : Univ. Press 33 (2013), 128-161
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OLC Linguistik
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8
Overcoming the effect of letter confusability in letter-by-letter reading: a rehabilitation study.
In: Symplectic Elements at Oxford ; Europe PubMed Central ; PubMed (http://www.ncbi.nlm.nih.gov/pubmed/) ; Web of Science (Lite) (http://apps.webofknowledge.com/summary.do) ; Scopus (http://www.scopus.com/home.url) ; CrossRef (2013)
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9
Phonological or procedural dyslexia: specific deficit of complex grapheme-to-phoneme conversion
In: Journal of neurolinguistics. - Orlando, Fla. : Elsevier 25 (2012) 3, 163-177
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OLC Linguistik
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10
How my brain stopped reading
In: Visible language. - Cincinnati, Ohio : University of Cincinnati 46 (2012) 3, 200-205
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OLC Linguistik
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11
Left- and right-hemisphere forms of phonological alexia
In: Cognitive neuropsychology. - Abingdon : Routledge, Taylor & Francis Group 29 (2012) 7-8, 531-549
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OLC Linguistik
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12
Changes in N400 topography following intensive speech language therapy for individuals with aphasia
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 123 (2012) 2, 94-103
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OLC Linguistik
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13
Covert reading of letters in a case of global alexia
In: Brain & language. - Orlando, Fla. [u.a.] : Elsevier 120 (2012) 3, 217-225
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OLC Linguistik
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14
Writing : a mosaic of new perspectives
Mambrino, Elisa (Hrsg.); Grigorenko, Elena L. (Hrsg.); Preiss, David (Hrsg.). - New York [u.a.] : Psychology Press, 2012
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UB Frankfurt Linguistik
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15
Progressive dyslexia: evidence from Hungarian and English.
In: Behav Neurol , 25 (3) 185 - 191. (2012) (2012)
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16
Case report: an approach to the patient with reading difficulties in the primary care setting
In: Journal of neurolinguistics. - Orlando, Fla. : Elsevier 24 (2011) 1, 89-95
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OLC Linguistik
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17
Do reading processes differ in transparent versus opaque orthographies? A study of acquired dyslexia in Welsh/English bilinguals
In: Cognitive neuropsychology. - Abingdon : Routledge, Taylor & Francis Group 28 (2011) 7-8, 546-563
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OLC Linguistik
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18
Temporal stability and representational distinctiveness: key functions of orthographic working memory
In: Cognitive neuropsychology. - Abingdon : Routledge, Taylor & Francis Group 28 (2011) 5-6, 338-362
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OLC Linguistik
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19
Complementary neural representations for faces and words: a computational exploration
In: Cognitive neuropsychology. - Abingdon : Routledge, Taylor & Francis Group 28 (2011) 3-4, 251-275
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OLC Linguistik
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20
Behavioral performances in participants with phonological dyslexia and different patterns on the N170 component
In: Brain and cognition. - San Diego, Calif. [u.a.] : Elsevier Science 75 (2011) 2, 91-100
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