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11041
A finer-grained linguistic profile of Alzheimer’s disease and Mild Cognitive Impairment
Abstract: Conté: Appendix A. Supplementary data ; Linguistic measures in spontaneous speech have shown promise in the early detection of Alzheimer’s disease (AD), but it remains unknown which specific linguistic variables show sensitivity and how language decline relates to primary memory deficits. We hypothesized that a set of finegrained linguistic variables relating specifically to forms of syntactic complexity involved in referencing objects and events as part of episodes would show sensitivity. We tested this in speech samples obtained from a picture description task, maximally isolating language deficits from the confound of episodic memory (EM) demands. 105 participants were split into Mild Cognitive Impairment (MCI), Mild-to-Moderate AD, and healthy controls (HC). Results showed that groups did not differ on generic linguistic variables such as number or length of utterances. However, AD relative to HC produced fewer embedded adjunct clauses, indefinite noun phrases, and Aspect marking, with moderate-to-large effect sizes. MCI compared to HC produced fewer adjunct clauses as well as fewer adverbial adjuncts. Together, these results confirm language impairment in AD and MCI at the level of specific linguistic variables relating to structures required for endowing narrative with specificity and episodic richness, independently of EM demands. ; This work was supported by grants MR/N013638/1 (St. Georges University of London, United Kingdom), FI-DGR, and SGR-1265 (both Generalitat de Catalunya), and by PID 2019-105241 GB-I00/AEI/10.13039/501100011033 financed by the Ministerio de Ciencia, Innovacion ´ y Universidades (MCIU) and by the Agencia Estatal de Investigacion ´ (AEI).
Keyword: Alzheimer’s disease; Grammar; Memory; Reference; Specificity; Spontaneous connected speech
URL: https://doi.org/10.1016/j.jneuroling.2022.101069
http://hdl.handle.net/10230/52790
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11042
Differences in language exposure and its effects on memory flexibility in monolingual, bilingual, and trilingual infants
Brito, Natalie H.; Barr, Rachel; Sebastián Gallés, Núria. - : Cambridge University Press
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11043
Brain activity during traditional textbook and audiovisual-3D learning
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11044
Predicting risk of dyslexia with an online gamified test
Rello, Luz, 1984-; Baeza Yates, Ricardo; Ali, Abdullah. - : Public Library of Science (PLoS)
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11045
Dependency grammar
Eades, D. - : Brill
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11046
Imágenes mentales, recuerdo y reconocimiento en sujetos altos en viveza de imagen ; Mental imagery, recall and recognition in high vivid imagery subjects
Campos García, Alfredo; Gómez Juncal, Rocío; Pérez Fabello, María José. - : Universidade do Minho. : Universidade da Coruña
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11047
Foreign language training to stimulate cognitive functions
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11048
Translation and questions of identity (review article in Arabic)
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11049
Carn Mor de Chlachan Beaga, A Large Cairn from Small Stones: Multivocality and Memory in Cape Breton Gaelic Singing
Conn, Stephanie. - NO_RESTRICTION
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11050
Implicit and Explicit Consequences of Distraction for Aging and Memory
Thomas, Ruthann C.. - WITHHELD_TWO_YEAR
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11051
The Effects of Bilingualism on Attention and Memory: Do Bilingual Advantages in Attention Lead to Disadvantages in Memory?
Braverman, Anna. - NO_RESTRICTION
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11052
Cognitive Abilities Underlying the Bilingual Advantage in Set Shifting
Nguyen, Thien-Kim. - NO_RESTRICTION
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11053
Revisiting Cognitive and Neuropsychological Novelty Effects
Poppenk, Jordan. - NO_RESTRICTION
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11054
Expressive language: age-related changes and the role of working memory
Heller, Robert Barry. - : University of Alberta. Department of Psychology.
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11055
Intertrial influences in a stroop-like task
Pilon, Daniel J. (Daniel Jean). - : University of Alberta. Department of Psychology.
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11056
Gene expression in learning & memory
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11057
The development of a brief Functional Magnetic Resonance Imaging test battery for neurofunctional investigation of language, memory encoding and motor function in normal children
Miss Christina Sveller. - : The University of Queensland, School of Psychology
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11058
Memory performance, oral comprehension and learning process between children with attention deficit hyperactivity disorder and children with anxiety disorder
In: Revista CEFAC, Vol 20, Iss 6, Pp 692-702
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11059
Relationship between cognitive and sociodemographic aspects and verbal fluency of active elderly
In: Revista CEFAC, Vol 20, Iss 4, Pp 493-502
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